{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Progressive+Cognitive+Decline&page=8",
    "query": {
      "condition": "Progressive Cognitive Decline",
      "page": 8
    },
    "page_size": 10
  },
  "pagination": {
    "page": 8,
    "page_size": 10,
    "total_count": 346,
    "total_pages": 35,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Progressive+Cognitive+Decline&page=9&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Progressive+Cognitive+Decline&page=7&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-26T08:40:50.410Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07210398",
      "title": "Mindfulness-based Cognitive Therapy for the Chronic Pain-early Cognitive Decline Co-morbidity Among Older Black Individuals in the Community; The Feeling of Being Open Pilot",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Early Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Mindfulness-based cognitive therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "50 Years to 120 Years"
      },
      "enrollment_count": 9,
      "start_date": "2024-12-05",
      "completion_date": "2025-07-22",
      "has_results": true,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07210398"
    },
    {
      "nct_id": "NCT06870136",
      "title": "Study Evaluating the Quality and Effects of Lion's Mane Product on Cognitive Health",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Lion's Mane Study Product",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "M2 Ingredients",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 150,
      "start_date": "2025-02-21",
      "completion_date": "2025-09-17",
      "has_results": false,
      "last_update_posted_date": "2025-03-11",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06870136"
    },
    {
      "nct_id": "NCT06914947",
      "title": "Brain Health Together: Development and Pilot Test",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cognitive Impairment",
        "Subjective Cognitive Decline",
        "Mild Cognitive Impairment (MCI)"
      ],
      "interventions": [
        {
          "name": "Brain Health Together",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2021-09-30",
      "completion_date": "2022-10-11",
      "has_results": false,
      "last_update_posted_date": "2025-04-10",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06914947"
    },
    {
      "nct_id": "NCT05592678",
      "title": "δ in Dementia Clinical Trials",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer's Disease (AD)",
        "Dementia",
        "Cognitive Decline",
        "Mild Cognitivie Impairment (MCI)"
      ],
      "interventions": [
        {
          "name": "Donepezil",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "65 Years to 100 Years"
      },
      "enrollment_count": 200,
      "start_date": "2024-08-05",
      "completion_date": "2028-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05592678"
    },
    {
      "nct_id": "NCT06162026",
      "title": "Cognitive Screening Made Easy for PCPs - R33 Phase",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Impairment",
        "Dementia, Mild",
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "RACS app",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2024-02-02",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-05",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06162026"
    },
    {
      "nct_id": "NCT07214974",
      "title": "Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Mild Cognitive Impairment (MCI)",
        "Early Stages of Cognitive Decline",
        "Alzheimer's Disease Dementia",
        "Alzheimer's Disease Diagnosis",
        "Alzheimer's Disease and Related Dementias",
        "Parkinson's Disease",
        "Parkinson's Disease (PD)",
        "Parkinson's Disease With Wearing-off Motor Fluctuations",
        "Dementia (Diagnosis)",
        "Dementia MCI (Mild Cognitive Impairment)"
      ],
      "interventions": [
        {
          "name": "Structured wellness care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Wearable brain-computer interface devices",
          "type": "DEVICE"
        },
        {
          "name": "Stem Cell Therapy - Experimental",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Control - Placebo Comparator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE",
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Noah Tech, Corp.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2026-09-01",
      "completion_date": "2030-01-03",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 1,
      "location_summary": "Palisades Park, New Jersey",
      "locations": [
        {
          "city": "Palisades Park",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07214974"
    },
    {
      "nct_id": "NCT04975464",
      "title": "BRINK (BRain In Kidney Disease) Memory Study 2.0",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Kidney Diseases",
        "Dementia",
        "Dementia, Vascular",
        "Stroke",
        "Alzheimer Disease",
        "Cognitive Decline",
        "Cognitive Impairment",
        "Cognitive Dysfunction",
        "Kidney Diseases",
        "Diabetes",
        "Cerebral Atrophy",
        "Small Vessel Ischemic Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Anne Murray",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2011-11-15",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2025-11-04",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 2,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04975464"
    },
    {
      "nct_id": "NCT07441122",
      "title": "Enhancing Attention in Elderly Using a Brain-Computer-Interface",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment (MCI)"
      ],
      "interventions": [
        {
          "name": "transcranial electrical stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Mindfulness Meditation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 100,
      "start_date": "2026-07-01",
      "completion_date": "2029-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-27",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 2,
      "location_summary": "Austin, Texas • Georgetown, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Georgetown",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07441122"
    },
    {
      "nct_id": "NCT00526942",
      "title": "Behavioral and Physiological Effects of Visual Training",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "SAAGE-designed, visual memory-based cognitive training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Posit Science Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2007-08",
      "completion_date": "2008-08",
      "has_results": false,
      "last_update_posted_date": "2007-09-11",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 1,
      "location_summary": "San Francisco Bay Area, California",
      "locations": [
        {
          "city": "San Francisco Bay Area",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00526942"
    },
    {
      "nct_id": "NCT00056225",
      "title": "VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Folate",
          "type": "DRUG"
        },
        {
          "name": "Vitamin B6",
          "type": "DRUG"
        },
        {
          "name": "Vitamin B12",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute on Aging (NIA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 340,
      "start_date": "2003-01",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2009-06-12",
      "last_synced_at": "2026-10-26T08:40:50.410Z",
      "location_count": 38,
      "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Sun City, Arizona + 29 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00056225"
    }
  ]
}