{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pulmonary+Hypertension%2C+Primary%2C+2", "query": { "condition": "Pulmonary Hypertension, Primary, 2" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 36, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pulmonary+Hypertension%2C+Primary%2C+2&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-10T10:43:33.081Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04712669", "title": "A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (Core OLE)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "rodatristat ethyl 300 mg tablet BID", "type": "DRUG" }, { "name": "rodatristat ethyl 600 mg BID", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Altavant Sciences GmbH", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 108, "start_date": "2021-03-15", "completion_date": "2023-08-28", "has_results": true, "last_update_posted_date": "2025-06-04", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 28, "location_summary": "Phoenix, Arizona • La Jolla, California • Los Angeles, California + 23 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04712669" }, { "nct_id": "NCT02725372", "title": "Clinical Study of Pulsed, Inhaled Nitric Oxide Versus Placebo in Symptomatic Subjects With PAH", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "Inhaled Nitric Oxide 75 mcg/kg IBW/hr", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bellerophon Pulse Technologies", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 207, "start_date": "2016-04", "completion_date": "2018-08", "has_results": true, "last_update_posted_date": "2023-02-21", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 37, "location_summary": "Phoenix, Arizona • Tucson, Arizona • Beverly Hills, California + 33 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02725372" }, { "nct_id": "NCT03449524", "title": "PRIMEx - A Study of 2 Doses of Oral CXA-10 in Pulmonary Arterial Hypertension (PAH)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "PAH" ], "interventions": [ { "name": "75mg CXA-10", "type": "DRUG" }, { "name": "150mg CXA-10", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Complexa, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 69, "start_date": "2018-08-01", "completion_date": "2020-08-05", "has_results": false, "last_update_posted_date": "2020-08-10", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 40, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 34 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03449524" }, { "nct_id": "NCT01725269", "title": "Long-term Study of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension Who Completed AIR001-CS05", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "AIR001", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aires Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 17, "start_date": "2013-03", "completion_date": "2014-04", "has_results": false, "last_update_posted_date": "2014-04-09", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 17, "location_summary": "La Jolla, California • Torrance, California • Aurora, Colorado + 12 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01725269" }, { "nct_id": "NCT05975905", "title": "A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "Dose A KER-012", "type": "BIOLOGICAL" }, { "name": "Dose B KER-012", "type": "BIOLOGICAL" }, { "name": "Dose C KER-012", "type": "BIOLOGICAL" }, { "name": "Placebo for 24 Weeks followed by Dose B KER-012 for 72 weeks", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Keros Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 113, "start_date": "2023-10-17", "completion_date": "2025-03-11", "has_results": false, "last_update_posted_date": "2025-09-30", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 16, "location_summary": "Scottsdale, Arizona • Tucson, Arizona • Stanford, California + 12 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Stanford", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05975905" }, { "nct_id": "NCT04053543", "title": "CXA-10 Study in Subjects With Pulmonary Arterial Hypertension", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "PAH" ], "interventions": [ { "name": "CXA-10", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Complexa, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2019-08-09", "completion_date": "2020-08-12", "has_results": false, "last_update_posted_date": "2020-08-26", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 31, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Anaheim, California + 27 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04053543" }, { "nct_id": "NCT05587712", "title": "Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "Sotatercept", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Merck Sharp & Dohme LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "17 Years", "sex": "ALL", "summary": "1 Year to 17 Years" }, "enrollment_count": 42, "start_date": "2023-01-19", "completion_date": "2028-09-21", "has_results": false, "last_update_posted_date": "2026-04-20", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 10, "location_summary": "Los Angeles, California • Palo Alto, California • San Francisco, California + 7 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05587712" }, { "nct_id": "NCT01265888", "title": "Study in Subjects With PAH and PH Secondary to IPF Using Inhaled GeNOsyl.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Arterial Hypertension", "Idiopathic Pulmonary Fibrosis" ], "interventions": [ { "name": "Inhaled Nitric Oxide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Geno LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 31, "start_date": "2011-03", "completion_date": "2016-09", "has_results": false, "last_update_posted_date": "2016-09-19", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 10, "location_summary": "Birmingham, Alabama • Los Angeles, California • Sacramento, California + 7 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Louisville", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT01265888" }, { "nct_id": "NCT07365332", "title": "An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pulmonary Arterial Hypertension" ], "interventions": [ { "name": "IKT-001", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Inhibikase Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 486, "start_date": "2026-04-23", "completion_date": "2029-12", "has_results": false, "last_update_posted_date": "2026-05-12", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 2, "location_summary": "Louisville, Kentucky • Boston, Massachusetts", "locations": [ { "city": "Louisville", "state": "Kentucky" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07365332" }, { "nct_id": "NCT04732221", "title": "A Study of the Efficacy and Safety of Frespaciguat (MK-5475) in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Pulmonary Arterial Hypertension", "Hypertension, Pulmonary" ], "interventions": [ { "name": "Frespaciguat", "type": "DRUG" }, { "name": "Placebo to Frespaciguat", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Merck Sharp & Dohme LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 168, "start_date": "2021-05-19", "completion_date": "2024-07-02", "has_results": true, "last_update_posted_date": "2025-05-25", "last_synced_at": "2026-06-10T10:43:33.081Z", "location_count": 26, "location_summary": "La Jolla, California • Sacramento, California • San Francisco, California + 22 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Greeley", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04732221" } ] }