{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pulmonary+Surfactant&page=2",
    "query": {
      "condition": "Pulmonary Surfactant",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pulmonary+Surfactant&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T09:38:34.503Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00628134",
      "title": "Self-dispersing Liquids as Aerosol Drug Carriers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "calfactant",
          "type": "DRUG"
        },
        {
          "name": "isotonic saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2008-03",
      "completion_date": "2009-08",
      "has_results": true,
      "last_update_posted_date": "2017-08-24",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00628134"
    },
    {
      "nct_id": "NCT04084093",
      "title": "Evaluating the Use of a Concentrated Surfactant Gel in Burn Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burns"
      ],
      "interventions": [
        {
          "name": "Surfactant Gel",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medline Industries",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-02-12",
      "completion_date": "2020-04-08",
      "has_results": false,
      "last_update_posted_date": "2020-04-20",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 2,
      "location_summary": "Maywood, Illinois • Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Maywood",
          "state": "Illinois"
        },
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04084093"
    },
    {
      "nct_id": "NCT02140580",
      "title": "OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Minimally invasive surfactant therapy",
          "type": "DEVICE"
        },
        {
          "name": "Continuation on CPAP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Menzies Institute for Medical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "1 Minute to 6 Hours"
      },
      "enrollment_count": 486,
      "start_date": "2011-12",
      "completion_date": "2022-06",
      "has_results": false,
      "last_update_posted_date": "2020-05-01",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 5,
      "location_summary": "New Haven, Connecticut • Honolulu, Hawaii • Evanston, Illinois + 2 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Camden",
          "state": "New Jersey"
        },
        {
          "city": "Morgantown",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02140580"
    },
    {
      "nct_id": "NCT01116921",
      "title": "Laryngeal Mask Airway (LMA) for Surfactant Administration in Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Nasal continuous positive airway pressure (nCPAP)",
          "type": "DEVICE"
        },
        {
          "name": "Laryngeal Mask Airway (LMA) to deliver surfactant",
          "type": "DEVICE"
        },
        {
          "name": "Surfactants, Pulmonary",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "36 Hours",
        "sex": "ALL",
        "summary": "Up to 36 Hours"
      },
      "enrollment_count": 103,
      "start_date": "2011-02",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2017-02-27",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 7,
      "location_summary": "Loma Linda, California • San Diego, California • Maple Grove, Minnesota + 4 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Maple Grove",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Robbinsdale",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01116921"
    },
    {
      "nct_id": "NCT00828243",
      "title": "Genetic Regulation of Surfactant Deficiency",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "Nutrient",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "1 Day to 6 Months"
      },
      "enrollment_count": 525,
      "start_date": "2007-11",
      "completion_date": "2013-03",
      "has_results": false,
      "last_update_posted_date": "2021-06-07",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00828243"
    },
    {
      "nct_id": "NCT06446453",
      "title": "Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn",
        "Pulmonary Surfactants",
        "Intensive Care Units, Neonatal"
      ],
      "interventions": [
        {
          "name": "Echography-guided Surfactant THERapy (ESTHER)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Connecticut Children's Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Hours",
        "maximum_age": "2 Hours",
        "sex": "ALL",
        "summary": "0 Hours to 2 Hours"
      },
      "enrollment_count": 52,
      "start_date": "2024-06-25",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 1,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06446453"
    },
    {
      "nct_id": "NCT03748173",
      "title": "Infasurf®(Calfactant) Aerosol for Infants With Bronchiolitis-AERO-04",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Bronchiolitis"
      ],
      "interventions": [
        {
          "name": "Aerosolized Infasurf",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "ONY",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Months",
        "maximum_age": "4 Months",
        "sex": "ALL",
        "summary": "0 Months to 4 Months"
      },
      "enrollment_count": 13,
      "start_date": "2019-01-12",
      "completion_date": "2020-10-21",
      "has_results": false,
      "last_update_posted_date": "2020-10-23",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03748173"
    },
    {
      "nct_id": "NCT00233324",
      "title": "Surfactant Positive Airway Pressure and Pulse Oximetry Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn, Diseases",
        "Other Preterm Infants",
        "Infant, Small for Gestational Age",
        "Premature Birth",
        "Bronchopulmonary Dysplasia",
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Surfactant",
          "type": "DRUG"
        },
        {
          "name": "Continuous Positive Airway Pressure (CPAP)",
          "type": "DEVICE"
        },
        {
          "name": "Supplemental oxygen with target saturation of 85 to 89%",
          "type": "DRUG"
        },
        {
          "name": "Supplemental oxygen with target saturation of 91 to 95%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Weeks",
        "maximum_age": "27 Weeks",
        "sex": "ALL",
        "summary": "24 Weeks to 27 Weeks"
      },
      "enrollment_count": 1316,
      "start_date": "2005-02",
      "completion_date": "2016-08",
      "has_results": true,
      "last_update_posted_date": "2019-04-18",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 22,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • San Diego, California + 18 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00233324"
    },
    {
      "nct_id": "NCT02772081",
      "title": "A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional Administration",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Distress Syndrome (RDS)"
      ],
      "interventions": [
        {
          "name": "LISA combination product (Curosurf+catheter CHF6440)",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Curosurf through conventional administration (endotracheal tube)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DRUG"
      ],
      "sponsor": "Chiesi Farmaceutici S.p.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Minutes",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "30 Minutes to 24 Hours"
      },
      "enrollment_count": 33,
      "start_date": "2021-05-18",
      "completion_date": "2022-08-13",
      "has_results": true,
      "last_update_posted_date": "2023-11-07",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 26,
      "location_summary": "Little Rock, Arkansas • Los Angeles, California • Denver, Colorado + 22 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "New Britain",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02772081"
    },
    {
      "nct_id": "NCT01268215",
      "title": "Pilot Study of Topical Steroid for Prevention of Chronic Lung Disease in Extremely Premature Infants.",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Infasurf",
          "type": "DRUG"
        },
        {
          "name": "Pulmicort",
          "type": "DRUG"
        },
        {
          "name": "Sham",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "East Carolina University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Weeks",
        "maximum_age": "28 Weeks",
        "sex": "ALL",
        "summary": "24 Weeks to 28 Weeks"
      },
      "enrollment_count": 45,
      "start_date": "2010-07",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2010-12-29",
      "last_synced_at": "2026-07-23T09:38:34.503Z",
      "location_count": 1,
      "location_summary": "Greenville, North Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01268215"
    }
  ]
}