{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pulmonary+Surfactants",
    "query": {
      "condition": "Pulmonary Surfactants"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 49,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Pulmonary+Surfactants&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T09:13:20.633Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02834624",
      "title": "Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Poractant alfa",
          "type": "DRUG"
        },
        {
          "name": "calfactant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Weeks",
        "maximum_age": "35 Weeks",
        "sex": "ALL",
        "summary": "22 Weeks to 35 Weeks"
      },
      "enrollment_count": 30,
      "start_date": "2013-07",
      "completion_date": "2015-07",
      "has_results": true,
      "last_update_posted_date": "2017-06-06",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02834624"
    },
    {
      "nct_id": "NCT02140580",
      "title": "OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Minimally invasive surfactant therapy",
          "type": "DEVICE"
        },
        {
          "name": "Continuation on CPAP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Menzies Institute for Medical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "1 Minute to 6 Hours"
      },
      "enrollment_count": 486,
      "start_date": "2011-12",
      "completion_date": "2022-06",
      "has_results": false,
      "last_update_posted_date": "2020-05-01",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 5,
      "location_summary": "New Haven, Connecticut • Honolulu, Hawaii • Evanston, Illinois + 2 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Camden",
          "state": "New Jersey"
        },
        {
          "city": "Morgantown",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02140580"
    },
    {
      "nct_id": "NCT01203358",
      "title": "Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn",
        "Infant, Low Birth Weight",
        "Infant, Small for Gestational Age",
        "Infant, Premature",
        "Bronchopulmonary Dysplasia"
      ],
      "interventions": [
        {
          "name": "Exosurf",
          "type": "DRUG"
        },
        {
          "name": "Survanta",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "Up to 6 Hours"
      },
      "enrollment_count": 617,
      "start_date": "1991-01",
      "completion_date": "1992-01",
      "has_results": false,
      "last_update_posted_date": "2019-03-22",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 13,
      "location_summary": "Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 10 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01203358"
    },
    {
      "nct_id": "NCT04502433",
      "title": "Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "CUROSURF® (poractant alfa)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Chiesi Farmaceutici S.p.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 22,
      "start_date": "2021-01-06",
      "completion_date": "2022-03-17",
      "has_results": true,
      "last_update_posted_date": "2023-06-23",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04502433"
    },
    {
      "nct_id": "NCT03582930",
      "title": "Aerosolized Infasurf Treatment Protocol: Aerosolized Infasurf for Spontaneously Breathing Patients With Early RDS (AERO-03)",
      "overall_status": "NO_LONGER_AVAILABLE",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Neonatal Respiratory Distress"
      ],
      "interventions": [
        {
          "name": "Infasurf Aero",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "ONY",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "42 Weeks",
        "sex": "ALL",
        "summary": "Up to 42 Weeks"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2023-11-07",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 5,
      "location_summary": "Jackson, Mississippi • Buffalo, New York • Greenville, North Carolina + 2 more",
      "locations": [
        {
          "city": "Jackson",
          "state": "Mississippi"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Greenville",
          "state": "North Carolina"
        },
        {
          "city": "Jackson",
          "state": "Tennessee"
        },
        {
          "city": "Provo",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03582930"
    },
    {
      "nct_id": "NCT05065424",
      "title": "Premedication for Less Invasive Surfactant Administration Study (PRELISA)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "IV Atropine and Fentanyl Premedication Arm",
          "type": "DRUG"
        },
        {
          "name": "IV Normal Saline Placebo Arm",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Hours",
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "0 Hours to 72 Hours"
      },
      "enrollment_count": 58,
      "start_date": "2022-04-06",
      "completion_date": "2026-03-02",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05065424"
    },
    {
      "nct_id": "NCT02907593",
      "title": "Steroids and Surfactant in Extremely Low Gestation Age Infants Dose Escalation Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia (BPD)"
      ],
      "interventions": [
        {
          "name": "Budesonide in Calfactant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cynthia McEvoy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Days",
        "maximum_age": "14 Days",
        "sex": "ALL",
        "summary": "3 Days to 14 Days"
      },
      "enrollment_count": 25,
      "start_date": "2016-09",
      "completion_date": "2018-04",
      "has_results": true,
      "last_update_posted_date": "2025-04-04",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 5,
      "location_summary": "San Francisco, California • Jacksonville, Florida • Orlando, Florida + 2 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02907593"
    },
    {
      "nct_id": "NCT03531996",
      "title": "The Longitudinal Evaluation of Autoimmune Pulmonary Alveolar Proteinosis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autoimmune Pulmonary Alveolar Proteinosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 29,
      "start_date": "2018-04-19",
      "completion_date": "2020-09-16",
      "has_results": false,
      "last_update_posted_date": "2021-06-24",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03531996"
    },
    {
      "nct_id": "NCT00014859",
      "title": "Epidemiology of Surfactant Protein-B Deficiency",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lung Diseases",
        "Respiratory Distress Syndrome, Newborn",
        "Pulmonary Surfactant",
        "Lung Diseases, Interstitial"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 5176,
      "start_date": "2001-06-01",
      "completion_date": "2024-04-26",
      "has_results": false,
      "last_update_posted_date": "2024-04-29",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00014859"
    },
    {
      "nct_id": "NCT04659122",
      "title": "A Clinical Safety Study on AT-100 in Treating Adults With Severe COVID-19 Infection or Severed Community Acquired Pneumonia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "COVID-19",
        "Undefined"
      ],
      "interventions": [
        {
          "name": "AT-100",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Airway Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2021-08-17",
      "completion_date": "2023-02-23",
      "has_results": false,
      "last_update_posted_date": "2023-08-14",
      "last_synced_at": "2026-07-22T09:13:20.633Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04659122"
    }
  ]
}