{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Quadriceps+Muscle+Function",
    "query": {
      "condition": "Quadriceps Muscle Function"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 19,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Quadriceps+Muscle+Function&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T07:38:37.134Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03132987",
      "title": "Characterizing Clinical and Biomechanical Contributions to Function Following ACL Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Tears"
      ],
      "interventions": [
        {
          "name": "Progressive strengthening program",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 39,
      "start_date": "2017-01",
      "completion_date": "2017-07-31",
      "has_results": false,
      "last_update_posted_date": "2017-08-17",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03132987"
    },
    {
      "nct_id": "NCT02095223",
      "title": "Effect of Electromyographic Biofeedback on Quadriceps Neuromuscular Function in Patients With Quadriceps Inhibition",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injuries"
      ],
      "interventions": [
        {
          "name": "Electromyographic Biofeedback",
          "type": "DEVICE"
        },
        {
          "name": "Traditional Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 4,
      "start_date": "2013-12",
      "completion_date": "2015-08",
      "has_results": true,
      "last_update_posted_date": "2017-02-01",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 1,
      "location_summary": "Coral Gables, Florida",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02095223"
    },
    {
      "nct_id": "NCT07128602",
      "title": "Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Reconstruction Rehabilitation",
        "Quadriceps Muscle Function"
      ],
      "interventions": [
        {
          "name": "active transcranial direct current stimulation (tDCS)",
          "type": "DEVICE"
        },
        {
          "name": "sham transcranial direct current stimulation (tDCS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Arcadia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 42,
      "start_date": "2025-06-06",
      "completion_date": "2028-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 1,
      "location_summary": "Glenside, Pennsylvania",
      "locations": [
        {
          "city": "Glenside",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07128602"
    },
    {
      "nct_id": "NCT04504344",
      "title": "Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Reconstruction",
        "Quadriceps Muscle Weakness",
        "Transcranial Direct Current Stimulation"
      ],
      "interventions": [
        {
          "name": "Anodal transcranial direct current stimulation (tDCS) - Soterix Medical Inc, 1x1 tDCS (conventional)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Arcadia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 20,
      "start_date": "2020-09-15",
      "completion_date": "2023-07-31",
      "has_results": false,
      "last_update_posted_date": "2023-08-09",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 1,
      "location_summary": "Glenside, Pennsylvania",
      "locations": [
        {
          "city": "Glenside",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04504344"
    },
    {
      "nct_id": "NCT00971451",
      "title": "Quadriceps Function Prior to Anterior Cruciate Ligament Reconstruction",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rupture of Anterior Cruciate Ligament"
      ],
      "interventions": [
        {
          "name": "cryotherapy",
          "type": "OTHER"
        },
        {
          "name": "TENS",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "15 Years to 55 Years"
      },
      "enrollment_count": 50,
      "start_date": "2007-11",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2011-03-08",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00971451"
    },
    {
      "nct_id": "NCT01555567",
      "title": "Electrical Stimulation and Eccentric Exercise for Anterior Cruciate Ligament (ACL) Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury"
      ],
      "interventions": [
        {
          "name": "Electrical Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Eccentric Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "14 Years to 35 Years"
      },
      "enrollment_count": 43,
      "start_date": "2009-08",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2015-06-08",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01555567"
    },
    {
      "nct_id": "NCT02058862",
      "title": "Effect of a Home-based Electrical Stimulation on Quadriceps Function After Knee Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post-operative Quadriceps Weakness",
        "Post-operative Quadriceps Inhibition",
        "Adherence to Post-operative Treatment",
        "Post-operative Lower Extremity Function"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Kentucky",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "12 Years to 60 Years"
      },
      "enrollment_count": 87,
      "start_date": "2014-05",
      "completion_date": "2018-10",
      "has_results": false,
      "last_update_posted_date": "2018-10-09",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 2,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02058862"
    },
    {
      "nct_id": "NCT03209531",
      "title": "Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury"
      ],
      "interventions": [
        {
          "name": "Operant Conditioning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Single Pulse Transcranial Magnetic Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 11,
      "start_date": "2017-09-21",
      "completion_date": "2025-11-24",
      "has_results": false,
      "last_update_posted_date": "2025-11-26",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03209531"
    },
    {
      "nct_id": "NCT04095442",
      "title": "Effect of Antibacterial Mouthwash on Muscle Function in Healthy Young Men and Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Quadriceps Muscle"
      ],
      "interventions": [
        {
          "name": "Cepacol",
          "type": "DEVICE"
        },
        {
          "name": "Tom's Natural Mouthwash",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 32,
      "start_date": "2019-11-01",
      "completion_date": "2023-03-20",
      "has_results": true,
      "last_update_posted_date": "2024-03-18",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04095442"
    },
    {
      "nct_id": "NCT03096366",
      "title": "Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Quadriceps Atrophy",
        "ACL Reconstruction"
      ],
      "interventions": [
        {
          "name": "Blood flow restriction",
          "type": "DEVICE"
        },
        {
          "name": "Physical therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "14 Years to 55 Years"
      },
      "enrollment_count": 150,
      "start_date": "2017-11-21",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2022-05-04",
      "last_synced_at": "2026-06-10T07:38:37.134Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03096366"
    }
  ]
}