{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=RDS+of+Prematurity&page=2",
    "query": {
      "condition": "RDS of Prematurity",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=RDS+of+Prematurity&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T14:20:21.766Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06776783",
      "title": "Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Distress Syndrome",
        "Pre-term Infants"
      ],
      "interventions": [
        {
          "name": "APC-0101 (SF-RI 1 surfactant for inhalation combined with a dedicated delivery system)",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "OTHER"
      ],
      "sponsor": "Aerogen Pharma Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 24 Hours"
      },
      "enrollment_count": 520,
      "start_date": "2025-09-24",
      "completion_date": "2029-05",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 12,
      "location_summary": "Little Rock, Arkansas • La Jolla, California • Jacksonville, Florida + 9 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "South Bend",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06776783"
    },
    {
      "nct_id": "NCT05961683",
      "title": "Evaluating Pressures During Non-invasive Ventilation Utilizing NIV Plus Software",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn",
        "Apnea of Newborn"
      ],
      "interventions": [
        {
          "name": "NIV plus software",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Keck School of Medicine of USC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "30 Days",
        "sex": "ALL",
        "summary": "0 Days to 30 Days"
      },
      "enrollment_count": 100,
      "start_date": "2023-08-01",
      "completion_date": "2024-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-07-27",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05961683"
    },
    {
      "nct_id": "NCT02528318",
      "title": "Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Lucinactant for inhalation",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "nCPAP alone",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DEVICE"
      ],
      "sponsor": "Windtree Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "26 Weeks",
        "maximum_age": "28 Weeks",
        "sex": "ALL",
        "summary": "26 Weeks to 28 Weeks"
      },
      "enrollment_count": 48,
      "start_date": "2015-08",
      "completion_date": "2017-08-11",
      "has_results": true,
      "last_update_posted_date": "2019-07-23",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 10,
      "location_summary": "Loma Linda, California • San Diego, California • Newark, Delaware + 7 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02528318"
    },
    {
      "nct_id": "NCT03670732",
      "title": "CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "Respiratory Distress Syndrome",
        "Apnea of Prematurity"
      ],
      "interventions": [
        {
          "name": "continuous positive airway pressure",
          "type": "OTHER"
        },
        {
          "name": "nasal intermittent positive pressure ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Women and Infants Hospital of Rhode Island",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 52,
      "start_date": "2017-09-30",
      "completion_date": "2020-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-07-30",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03670732"
    },
    {
      "nct_id": "NCT03938532",
      "title": "Feasibility and Impact of Volume Targeted Ventilation in the Delivery Room",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "BPD - Bronchopulmonary Dysplasia",
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "Volume Targeted Ventilation (VTV) using the Philips Respironics NM3 monitor",
          "type": "DEVICE"
        },
        {
          "name": "Tidal Volume Measurement using the Philips Respironics NM3 monitor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baystate Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Minutes",
        "maximum_age": "60 Minutes",
        "sex": "ALL",
        "summary": "5 Minutes to 60 Minutes"
      },
      "enrollment_count": 20,
      "start_date": "2019-07-11",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-02-05",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 1,
      "location_summary": "Springfield, Massachusetts",
      "locations": [
        {
          "city": "Springfield",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03938532"
    },
    {
      "nct_id": "NCT01220687",
      "title": "Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome in Premature Infants",
        "Very Low Birth Weight Baby"
      ],
      "interventions": [
        {
          "name": "iNO",
          "type": "DRUG"
        },
        {
          "name": "Nitrogen",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "2 Minutes",
        "sex": "ALL",
        "summary": "1 Minute to 2 Minutes"
      },
      "enrollment_count": 33,
      "start_date": "2011-04",
      "completion_date": "2017-05-01",
      "has_results": true,
      "last_update_posted_date": "2020-08-19",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 2,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01220687"
    },
    {
      "nct_id": "NCT06038565",
      "title": "Comparing Different Delivery Systems of Continuous Positive Airway Pressure in Neonates",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "RAM cannula ventilator CPAP",
          "type": "DEVICE"
        },
        {
          "name": "Occlusive interface bubble CPAP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Hours",
        "maximum_age": "36 Hours",
        "sex": "ALL",
        "summary": "12 Hours to 36 Hours"
      },
      "enrollment_count": 0,
      "start_date": "2023-10-18",
      "completion_date": "2024-04-11",
      "has_results": false,
      "last_update_posted_date": "2024-07-08",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06038565"
    },
    {
      "nct_id": "NCT02452476",
      "title": "A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "CHF5633",
          "type": "DRUG"
        },
        {
          "name": "Poractant alfa",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Chiesi Farmaceutici S.p.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 24 Hours"
      },
      "enrollment_count": 123,
      "start_date": "2016-01-21",
      "completion_date": "2018-05-24",
      "has_results": true,
      "last_update_posted_date": "2021-08-13",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 23,
      "location_summary": "Mobile, Alabama • Los Angeles, California • Orange, California + 20 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02452476"
    },
    {
      "nct_id": "NCT03346343",
      "title": "Pulmonary Function Using Non-invasive Forced Oscillometry",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Premature, Diseases",
        "Infant, Newborn, Diseases",
        "Bronchopulmonary Dysplasia",
        "Respiratory Distress Syndrome, Newborn",
        "Meconium Aspiration Syndrome",
        "Transient Tachypnea of the Newborn"
      ],
      "interventions": [
        {
          "name": "Non-invasive forced airway oscillometry",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "1 Day to 2 Years"
      },
      "enrollment_count": 600,
      "start_date": "2017-12-06",
      "completion_date": "2027-05",
      "has_results": true,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03346343"
    },
    {
      "nct_id": "NCT00767039",
      "title": "Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Prematurity",
        "Respiratory Distress Syndrome",
        "Patent Ductus Arteriosus"
      ],
      "interventions": [
        {
          "name": "Survanta (beractant)",
          "type": "DRUG"
        },
        {
          "name": "Curosurf (poractant)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alan Fujii",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "8 Hours",
        "sex": "ALL",
        "summary": "Up to 8 Hours"
      },
      "enrollment_count": 52,
      "start_date": "2005-01",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2011-10-03",
      "last_synced_at": "2026-07-23T14:20:21.766Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00767039"
    }
  ]
}