{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=REM+Sleep+Behavior+Disorder",
    "query": {
      "condition": "REM Sleep Behavior Disorder"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 41,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=REM+Sleep+Behavior+Disorder&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-21T22:55:33.368Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01453127",
      "title": "DaTSCAN Imaging in Aging and Neurodegenerative Disease",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dementia",
        "Parkinsonism",
        "Mild Cognitive Impairment",
        "REM Sleep Behavior Disorder"
      ],
      "interventions": [
        {
          "name": "I-123 Ioflupane solution injection prior to SPECT scan (DaTscan)",
          "type": "DRUG"
        },
        {
          "name": "Single photon emission computed tomography (SPECT) scan",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "40 Years to 90 Years"
      },
      "enrollment_count": 500,
      "start_date": "2011-10",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01453127"
    },
    {
      "nct_id": "NCT07217054",
      "title": "Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior Disorder",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PARKINSON DISEASE (Disorder)",
        "Parkinson",
        "Parkinson s Disease",
        "Parkinson Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "CND Life Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "40 Years to 99 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-11-04",
      "completion_date": "2029-10",
      "has_results": false,
      "last_update_posted_date": "2026-02-11",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 1,
      "location_summary": "Branford, Connecticut",
      "locations": [
        {
          "city": "Branford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07217054"
    },
    {
      "nct_id": "NCT07190287",
      "title": "Wearable Neural Interfacing System for REM Sleep Restoration and Enhancement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disturbance",
        "Stress, Psychological",
        "REM Sleep Measurement"
      ],
      "interventions": [
        {
          "name": "NEUSleeP system (FUS-EEG wearable device)",
          "type": "DEVICE"
        },
        {
          "name": "BrainSonix Pulsar 1002",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 52,
      "start_date": "2025-07-15",
      "completion_date": "2025-10-03",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07190287"
    },
    {
      "nct_id": "NCT05109364",
      "title": "Terazosin and Parkinson's Disease Extension Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Symptomatic Parkinson Disease",
        "REM Sleep Behavior Disorder",
        "Pre-motor Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "Terazosin therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 15,
      "start_date": "2022-09-23",
      "completion_date": "2026-03-10",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05109364"
    },
    {
      "nct_id": "NCT05922995",
      "title": "The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "REM Behavior Disorder"
      ],
      "interventions": [
        {
          "name": "Tasimelteon",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 20,
      "start_date": "2023-09-30",
      "completion_date": "2023-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-09",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05922995"
    },
    {
      "nct_id": "NCT01342328",
      "title": "Providing \"Good Sleep\" for ICU Sedation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disorders"
      ],
      "interventions": [
        {
          "name": "Normal saline infusion",
          "type": "OTHER"
        },
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Propofol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 3,
      "start_date": "2012-05",
      "completion_date": "2018-11-01",
      "has_results": false,
      "last_update_posted_date": "2018-12-19",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01342328"
    },
    {
      "nct_id": "NCT05826457",
      "title": "North American Prodromal Synucleinopathy Consortium Stage 2",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "REM Sleep Behavior Disorder",
        "Parkinson Disease",
        "Lewy Body Dementia",
        "Dementia With Lewy Bodies",
        "Multiple System Atrophy",
        "REM Sleep Parasomnias"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2022-08-12",
      "completion_date": "2028-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-13",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Redwood City, California • Atlanta, Georgia + 5 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05826457"
    },
    {
      "nct_id": "NCT02640339",
      "title": "Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parkinson Disease",
        "Multiple System Atrophy",
        "REM Sleep Behavior Disorder",
        "Pure Autonomic Failure",
        "Dementia With Lewy Bodies"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 166,
      "start_date": "2016-02",
      "completion_date": "2020-10-31",
      "has_results": false,
      "last_update_posted_date": "2020-12-02",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02640339"
    },
    {
      "nct_id": "NCT06996652",
      "title": "An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "REM Sleep Behavior Disorder"
      ],
      "interventions": [
        {
          "name": "Adalimumab",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 108,
      "start_date": "2026-05",
      "completion_date": "2029-08",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 19,
      "location_summary": "Los Angeles, California • Aurora, Colorado • North Haven, Connecticut + 15 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "North Haven",
          "state": "Connecticut"
        },
        {
          "city": "Boca Raton",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06996652"
    },
    {
      "nct_id": "NCT01799915",
      "title": "Natural History Study of Synucleinopathies",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Patients With Synucleinopathies",
        "Neurogenic Orthostatic Hypotension",
        "Pure Autonomic Failure",
        "REM Sleep Behavior Disorder",
        "Parkinson Disease",
        "Dementia With Lewy Bodies",
        "Multiple System Atrophy",
        "Shy-Drager Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 800,
      "start_date": "2011-06",
      "completion_date": "2026-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-11",
      "last_synced_at": "2026-05-21T22:55:33.368Z",
      "location_count": 5,
      "location_summary": "Boston, Massachusetts • Ann Arbor, Michigan • Rochester, Minnesota + 2 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01799915"
    }
  ]
}