{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=REM+Sleep+Behavior+Disorder&page=2",
    "query": {
      "condition": "REM Sleep Behavior Disorder",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=REM+Sleep+Behavior+Disorder&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-21T23:45:07.121Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02871427",
      "title": "Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lewy Body Dementia",
        "Dementia With Lewy Bodies",
        "Parkinson's Disease Dementia",
        "Visual Hallucinations",
        "REM Sleep Behavior Disorder"
      ],
      "interventions": [
        {
          "name": "Nelotanserin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Axovant Sciences Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2016-10-20",
      "completion_date": "2019-01-17",
      "has_results": false,
      "last_update_posted_date": "2019-03-27",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 19,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Boca Raton, Florida + 16 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Boca Raton",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Ocala",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02871427"
    },
    {
      "nct_id": "NCT06441864",
      "title": "Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nightmare",
        "Nightmare Disorder With Associated Other Sleep Disorder",
        "REM Sleep Behavior Disorder"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Nightmares",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2024-07-15",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-12",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06441864"
    },
    {
      "nct_id": "NCT05757206",
      "title": "The Syn-Sleep Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "REM Sleep Behavior Disorder (iRBD)"
      ],
      "interventions": [
        {
          "name": "Syn-One Test",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "CND Life Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 80,
      "start_date": "2022-09-15",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-01-15",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 8,
      "location_summary": "Chandler, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 5 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05757206"
    },
    {
      "nct_id": "NCT01547481",
      "title": "MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Movement Disorders (Incl Parkinsonism)",
        "Tremor Familial Essential, 1",
        "REM Sleep Behavior Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "19 Years to 85 Years"
      },
      "enrollment_count": 50,
      "start_date": "2011-12",
      "completion_date": "2015-12-31",
      "has_results": false,
      "last_update_posted_date": "2018-05-17",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01547481"
    },
    {
      "nct_id": "NCT04886076",
      "title": "Sleep Profiles in REM Sleep Behavior Disorder",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rapid Eye Movement Sleep Behavior Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2018-12-07",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2025-11-05",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04886076"
    },
    {
      "nct_id": "NCT00745030",
      "title": "Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "REM Behavior Disorder",
        "Parkinsonism"
      ],
      "interventions": [
        {
          "name": "Rozerem",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 3,
      "start_date": "2008-06",
      "completion_date": "2009-12",
      "has_results": true,
      "last_update_posted_date": "2024-01-09",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00745030"
    },
    {
      "nct_id": "NCT01401413",
      "title": "Study to Determine Whether Ramelteon Helps People With REM Sleep Behavior Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "REM Sleep Behavior Disorder"
      ],
      "interventions": [
        {
          "name": "ramelteon",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sleep Medicine Centers of WNY",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 20,
      "start_date": "2008-01",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2011-07-25",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 1,
      "location_summary": "West Seneca, New York",
      "locations": [
        {
          "city": "West Seneca",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01401413"
    },
    {
      "nct_id": "NCT04020198",
      "title": "A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Parkinson Disease",
        "Multiple System Atrophy",
        "Rapid Eye Movement Sleep Behavior Disorder",
        "Normal Pressure Hydrocephalus"
      ],
      "interventions": [
        {
          "name": "Biomarker assay",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 8,
      "start_date": "2020-01-15",
      "completion_date": "2022-10-19",
      "has_results": false,
      "last_update_posted_date": "2025-04-06",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04020198"
    },
    {
      "nct_id": "NCT03775096",
      "title": "Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "REM Sleep Behavior Disorder",
        "Pre-motor Parkinson Disease",
        "Symptomatic Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Carvedilol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Michele Tagliati, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 15,
      "start_date": "2019-04-04",
      "completion_date": "2026-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03775096"
    },
    {
      "nct_id": "NCT05307770",
      "title": "Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rapid Eye Movement Sleep Behavior Disorder",
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Immediate Release Melatonin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Extended Release Melatonin",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2022-05-01",
      "completion_date": "2024-02-01",
      "has_results": false,
      "last_update_posted_date": "2024-05-29",
      "last_synced_at": "2026-05-21T23:45:07.121Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05307770"
    }
  ]
}