{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=RVOT+Anomaly", "query": { "condition": "RVOT Anomaly" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 7, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-22T02:09:57.121Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05077774", "title": "Harmony TPV Post-Approval Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Congenital Heart Disease", "Tetrology of Fallot", "RVOT Anomaly", "Pulmonary Regurgitation" ], "interventions": [ { "name": "Harmony TPV System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medtronic Cardiovascular", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 174, "start_date": "2021-10-25", "completion_date": "2035-03", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-07-22T02:09:57.121Z", "location_count": 19, "location_summary": "Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 15 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Tampa", "state": "Florida" }, { "city": "Oak Lawn", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05077774" }, { "nct_id": "NCT02744677", "title": "COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Complex Congenital Heart Defect", "Dysfunctional RVOT Conduit", "Pulmonary Valve Insufficiency", "Pulmonary Valve Degeneration" ], "interventions": [ { "name": "SAPIEN 3/SAPIEN 3 Ultra RESILIA THV", "type": "DEVICE" }, { "name": "SAPIEN 3 THV", "type": "DEVICE" }, { "name": "SAPIEN 3 Ultra RESILIA THV", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Edwards Lifesciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 108, "start_date": "2016-07-05", "completion_date": "2031-06", "has_results": false, "last_update_posted_date": "2026-03-06", "last_synced_at": "2026-07-22T02:09:57.121Z", "location_count": 25, "location_summary": "Little Rock, Arkansas • Los Angeles, California • San Francisco, California + 18 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02744677" }, { "nct_id": "NCT05378386", "title": "ALTERRA Post-Approval Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pulmonary Valve Insufficiency", "Complex Congenital Heart Defect", "Tetralogy of Fallot", "Pulmonary Regurgitation", "RVOT Anomaly" ], "interventions": [ { "name": "Edwards Alterra Adaptive Prestent with SAPIEN 3 Transcatheter Pulmonary Valve System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Edwards Lifesciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 150, "start_date": "2022-05-12", "completion_date": "2035-07", "has_results": false, "last_update_posted_date": "2025-11-04", "last_synced_at": "2026-07-22T02:09:57.121Z", "location_count": 23, "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 18 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05378386" }, { "nct_id": "NCT02979587", "title": "The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Congenital Heart Disease", "Tetrology of Fallot", "RVOT Anomaly", "Pulmonary Regurgitation" ], "interventions": [ { "name": "Harmony TPV System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medtronic Heart Valves", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 86, "start_date": "2017-01", "completion_date": "2031-02", "has_results": true, "last_update_posted_date": "2025-09-19", "last_synced_at": "2026-07-22T02:09:57.121Z", "location_count": 9, "location_summary": "Los Angeles, California • Palo Alto, California • New Haven, Connecticut + 6 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Rochester", "state": "Minnesota" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02979587" }, { "nct_id": "NCT00740870", "title": "Melody Transcatheter Pulmonary Valve Study: Post Approval Study of the Investigational Device Exemption Cohort", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Congenital Heart Defects", "Dysfunctional Right Ventricular Outflow Tract Conduits" ], "interventions": [ { "name": "Transcatheter Pulmonary Valve replacement", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medtronic Cardiovascular", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": null, "sex": "ALL", "summary": "5 Years and older" }, "enrollment_count": 171, "start_date": "2007-01", "completion_date": "2020-08-21", "has_results": true, "last_update_posted_date": "2024-03-26", "last_synced_at": "2026-07-22T02:09:57.121Z", "location_count": 5, "location_summary": "Miami, Florida • Boston, Massachusetts • New York, New York + 2 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00740870" }, { "nct_id": "NCT00676689", "title": "COMPASSION - COngenital Multicenter Trial of Pulmonic VAlve Regurgitation Studying the SAPIEN InterventIONal THV", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pulmonary Valve Insufficiency", "Pulmonary Regurgitation", "Dysfunctional RVOT Conduit", "Pulmonary Obstruction", "Pulmonary Stenosis" ], "interventions": [ { "name": "SAPIEN Transcatheter Valve Implantation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Edwards Lifesciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 81, "start_date": "2008-04-08", "completion_date": "2019-12-31", "has_results": true, "last_update_posted_date": "2020-02-26", "last_synced_at": "2026-07-22T02:09:57.121Z", "location_count": 7, "location_summary": "Los Angeles, California • Miami, Florida • Atlanta, Georgia + 4 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT00676689" }, { "nct_id": "NCT03022708", "title": "Xeltis Bioabsorbable Pulmonary Valved Conduit Pivotal Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Defect, Congenital" ], "interventions": [ { "name": "Xeltis Bioabsorbable Pulmonary Valved Conduit", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Xeltis", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "2 Years to 21 Years" }, "enrollment_count": 56, "start_date": "2017-05-08", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2025-07-22", "last_synced_at": "2026-07-22T02:09:57.121Z", "location_count": 7, "location_summary": "Los Angeles, California • Aurora, Colorado • Hollywood, Florida + 4 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Hollywood", "state": "Florida" }, { "city": "New York", "state": "New York" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03022708" } ] }