{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Radiation%3B+Reaction",
    "query": {
      "condition": "Radiation; Reaction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T13:03:21.198Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00253981",
      "title": "Light Therapy in the Treatment of Leg Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tibial Fractures",
        "Leg Injuries"
      ],
      "interventions": [
        {
          "name": "Monochromatic Near-Infrared Light Energy (MIRE)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Samueli Institute for Information Biology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 30,
      "start_date": "2005-11",
      "completion_date": "2008-11",
      "has_results": true,
      "last_update_posted_date": "2016-06-13",
      "last_synced_at": "2026-09-07T13:03:21.198Z",
      "location_count": 1,
      "location_summary": "El Paso, Texas",
      "locations": [
        {
          "city": "El Paso",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00253981"
    },
    {
      "nct_id": "NCT03610711",
      "title": "REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Gastroesophageal Cancer",
        "Immune Checkpoint Inhibition"
      ],
      "interventions": [
        {
          "name": "Nivolumab",
          "type": "DRUG"
        },
        {
          "name": "Relatlimab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 21,
      "start_date": "2019-03-06",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-09-07T13:03:21.198Z",
      "location_count": 3,
      "location_summary": "Baltimore, Maryland • Pittsburgh, Pennsylvania • Dallas, Texas",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03610711"
    },
    {
      "nct_id": "NCT05775601",
      "title": "18F-LY3950321-01 Biodistribution and Safety Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Diagnostic Agent Adverse Reaction",
        "Radiation Exposure"
      ],
      "interventions": [
        {
          "name": "18F-LY3950321",
          "type": "DRUG"
        },
        {
          "name": "PET Scan",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Avid Radiopharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2023-02-28",
      "completion_date": "2023-04-04",
      "has_results": false,
      "last_update_posted_date": "2023-04-28",
      "last_synced_at": "2026-09-07T13:03:21.198Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05775601"
    },
    {
      "nct_id": "NCT03287349",
      "title": "Genomic Assessment of Patients With Severe Radiation Reactions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Radiation; Reaction"
      ],
      "interventions": [
        {
          "name": "Blood draw",
          "type": "OTHER"
        },
        {
          "name": "Photograph",
          "type": "OTHER"
        },
        {
          "name": "Autoimmune testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2017-05-10",
      "completion_date": "2023-01-04",
      "has_results": false,
      "last_update_posted_date": "2024-11-15",
      "last_synced_at": "2026-09-07T13:03:21.198Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03287349"
    },
    {
      "nct_id": "NCT04821245",
      "title": "Defining Normal Postoperative Magnetic Resonance Imaging After Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Local Anesthetic Complication",
        "Local Anesthetic Drug Adverse Reaction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Benaroya Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 36,
      "start_date": "2018-12-04",
      "completion_date": "2019-08-02",
      "has_results": true,
      "last_update_posted_date": "2021-05-25",
      "last_synced_at": "2026-09-07T13:03:21.198Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04821245"
    },
    {
      "nct_id": "NCT05559697",
      "title": "Study Comparing iNPWT Dressing and Devices Affect on Bioburden Levels and Skin Condition After Seven Days",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Reaction to Mechanical, Thermal and Radiation Stimuli",
        "Skin Sensitisation"
      ],
      "interventions": [
        {
          "name": "Sponsor incisional negative pressure wound therapy device and dressing",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care incisional negative pressure wound therapy system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DeRoyal Industries, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 16,
      "start_date": "2024-02-26",
      "completion_date": "2024-03-07",
      "has_results": false,
      "last_update_posted_date": "2024-03-12",
      "last_synced_at": "2026-09-07T13:03:21.198Z",
      "location_count": 1,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05559697"
    },
    {
      "nct_id": "NCT03056378",
      "title": "POOLED Red Blood Cells Prepared From Pooling 5 Leukoreduced, Irradiated RBC Units",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Transfusion Reaction",
        "Anemia"
      ],
      "interventions": [
        {
          "name": "Standard RBCs",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "New York Blood Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-10",
      "completion_date": "2021-06",
      "has_results": false,
      "last_update_posted_date": "2019-12-26",
      "last_synced_at": "2026-09-07T13:03:21.198Z",
      "location_count": 1,
      "location_summary": "Valhalla, New York",
      "locations": [
        {
          "city": "Valhalla",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03056378"
    }
  ]
}