{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Reduced+Ventricular+Ejection+Fraction", "query": { "condition": "Reduced Ventricular Ejection Fraction" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 31, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Reduced+Ventricular+Ejection+Fraction&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-04T22:23:07.031Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01970501", "title": "Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Current or Recent History of Atrial Fibrillation" ], "interventions": [ { "name": "bucindolol hydrochloride", "type": "DRUG" }, { "name": "metoprolol succinate", "type": "DRUG" }, { "name": "Placebo oral capsule", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "ARCA Biopharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 267, "start_date": "2014-04", "completion_date": "2017-12-28", "has_results": true, "last_update_posted_date": "2022-09-26", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 48, "location_summary": "Anchorage, Alaska • Phoenix, Arizona • East Palo Alto, California + 43 more", "locations": [ { "city": "Anchorage", "state": "Alaska" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "East Palo Alto", "state": "California" }, { "city": "Loma Linda", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01970501" }, { "nct_id": "NCT06935370", "title": "A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "vicadrostat", "type": "DRUG" }, { "name": "empagliflozin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4200, "start_date": "2025-05-20", "completion_date": "2029-02-22", "has_results": false, "last_update_posted_date": "2026-09-03", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 91, "location_summary": "Beverly Hills, California • Covina, California • Encinitas, California + 77 more", "locations": [ { "city": "Beverly Hills", "state": "California" }, { "city": "Covina", "state": "California" }, { "city": "Encinitas", "state": "California" }, { "city": "Merced", "state": "California" }, { "city": "Newport Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06935370" }, { "nct_id": "NCT04400435", "title": "Detection of Heart Conditions With Single Lead ECG Using Artificial Intelligence", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Left Ventricular Dysfunction" ], "interventions": [ { "name": "Use of Eko DUO electronic stethoscope", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Eko Devices, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1258, "start_date": "2020-07-15", "completion_date": "2022-04-29", "has_results": false, "last_update_posted_date": "2022-12-09", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 3, "location_summary": "Los Alamitos, California • Washington D.C., District of Columbia • Philadelphia, Pennsylvania", "locations": [ { "city": "Los Alamitos", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04400435" }, { "nct_id": "NCT00401687", "title": "DMP115 in Patients With an Ejection Fraction Between 25%-40% to Evaluate the Use of Contrast Echocardiography to Assess Heart Function", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Ventricular Ejection Fraction" ], "interventions": [ { "name": "Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Lantheus Medical Imaging", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 131, "start_date": "2006-07", "completion_date": "2008-04", "has_results": false, "last_update_posted_date": "2011-05-20", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 10, "location_summary": "Tucson, Arizona • Chicago, Illinois • Washington DC, Maryland + 7 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Washington DC", "state": "Maryland" }, { "city": "Kansas City", "state": "Missouri" }, { "city": "Omaha", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT00401687" }, { "nct_id": "NCT01354613", "title": "Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Failure With Preserved Ejection Fraction", "Pulmonary Disease", "Left Ventricular Hypertrophy/Hypertension" ], "interventions": [ { "name": "Dobutamine", "type": "DRUG" }, { "name": "Amlodipine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2011-04", "completion_date": "2013-12", "has_results": false, "last_update_posted_date": "2019-04-11", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01354613" }, { "nct_id": "NCT06763549", "title": "COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cardiopulmonary Failure", "Myocardial Infarction (MI)", "Heart Decompensation", "Heart Failure", "HFrEF - Heart Failure with Reduced Ejection Fraction", "HFpEF - Heart Failure with Preserved Ejection Fraction", "Syncopation", "Syncope", "Ischemic Cardiovascular Disease", "STEMI", "STEMI (ST Elevation MI)", "Atrial Fibrillation (AF)", "Atrial Enlargement", "LVF", "Conduction Defect", "Conduction Abnormalities", "Heart Block", "Valvular Diseases", "Cardiac Output, Low", "Stroke Volume", "Stroke Volume Variation", "Hyperkalemia", "Hypercalcemia", "Hypocalcemia", "LV Dysfunction", "QT Prolongation", "Sudden Cardiac Death Due to Cardiac Arrhythmia", "Ventricular Arrhythmia", "Pacing", "Pacing Induced Dyssynchrony", "Silent Ischemia", "Pericarditis", "Sleep Related Breathing Disorder", "RSA", "Apnea, Obstructive", "Cardiac Output Measurement", "Respiratory Impedance", "CRT And/or ICD", "Infarction", "Cardiomyopathies, Primary", "Hypertrophy" ], "interventions": [ { "name": "SUBPROTOCOL A", "type": "DEVICE" }, { "name": "SUBPROTOCOL B", "type": "DEVICE" }, { "name": "SUBPROTOCOL C", "type": "DEVICE" }, { "name": "SUBPROTOCOL D", "type": "DEVICE" }, { "name": "SUBPROTOCOL E", "type": "DEVICE" }, { "name": "SUBPROTOCOL F", "type": "DEVICE" }, { "name": "SUBPROTOCOL G", "type": "DEVICE" }, { "name": "SUBPROTOCOL H", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Peerbridge Health, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15000, "start_date": "2024-11-16", "completion_date": "2026-04-15", "has_results": false, "last_update_posted_date": "2025-01-08", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 1, "location_summary": "Melbourne, Florida", "locations": [ { "city": "Melbourne", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06763549" }, { "nct_id": "NCT07800962", "title": "Federated Learning for Point-of-Care Cardiac Ultrasound", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Ventricular Dysfunction, Left", "Ventricular Function, Left", "Echocardiography", "Ultrasonography", "Point-of-Care Systems", "Heart Function Tests", "Stroke Volume", "Federated Learning", "Machine Learning", "Artificial Intelligence (AI)", "Deep Learning", "Neural Networks, Computer", "Image Interpretation, Computer-Assisted", "Diagnosis, Computer-Assisted", "Sensitivity and Specificity", "ROC Curve" ], "interventions": [ { "name": "Focused Cardiac Point-of-Care Ultrasonography", "type": "DIAGNOSTIC_TEST" }, { "name": "FL-POCUS Federated Machine-Learning Analysis System", "type": "DEVICE" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "DEVICE" ], "sponsor": "Truway Health, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3000, "start_date": "2026-08-31", "completion_date": "2037-09-30", "has_results": false, "last_update_posted_date": "2026-09-02", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07800962" }, { "nct_id": "NCT04331769", "title": "Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Failure With Reduced Ejection Fraction (HFrEF)", "Dilated Cardiomyopathy" ], "interventions": [ { "name": "AccuCinch Ventricular Restoration System", "type": "DEVICE" }, { "name": "Guideline-Directed Medical Therapy", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Ancora Heart, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 400, "start_date": "2020-12-21", "completion_date": "2030-12-21", "has_results": false, "last_update_posted_date": "2026-06-03", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 96, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 75 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04331769" }, { "nct_id": "NCT07215715", "title": "US Benchmarking Clinical Study", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "HFpEF - Heart Failure With Preserved Ejection Fraction", "HFmrEF", "ATTR-CM (Transthyretin Amyloid Cardiomyopathy)", "Left Ventricular Hypertrophy", "Cardiac Amyloidosis" ], "interventions": [], "intervention_types": [], "sponsor": "eMyosound SAS", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 150, "start_date": "2025-09-16", "completion_date": "2026-07", "has_results": false, "last_update_posted_date": "2025-10-20", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 3, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07215715" }, { "nct_id": "NCT03387163", "title": "Patient Reported Outcomes inVestigation Following Initiation of Drug Therapy With Entresto (Sacubitril/Valsartan) in Heart Failure", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Heart Failure, Systolic" ], "interventions": [ { "name": "Sacubitril/Valsartan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 402, "start_date": "2018-02-09", "completion_date": "2019-06-21", "has_results": false, "last_update_posted_date": "2019-12-13", "last_synced_at": "2026-09-04T22:23:07.031Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03387163" } ] }