{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Reflex+Syncope",
    "query": {
      "condition": "Reflex Syncope"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 17,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Reflex+Syncope&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:44:33.051Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02558972",
      "title": "Northera Improves Postural Tachycardia Syndrome (POTS) and Postural Vasovagal Syncope (VVS)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postural Tachycardia Syndrome (POTS)",
        "Vasovagal Syncope (VVS)",
        "Fainting"
      ],
      "interventions": [
        {
          "name": "Northera (Droxidopa)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 30,
      "start_date": "2015-09",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 1,
      "location_summary": "Hawthorne, New York",
      "locations": [
        {
          "city": "Hawthorne",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02558972"
    },
    {
      "nct_id": "NCT01692561",
      "title": "MRI to Assess the Effects of Dysautonomia and Chronic Nausea on Brain Transmitters",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dysautonomia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "9 Years to 18 Years"
      },
      "enrollment_count": 22,
      "start_date": "2012-08",
      "completion_date": "2013-06-11",
      "has_results": false,
      "last_update_posted_date": "2018-04-27",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01692561"
    },
    {
      "nct_id": "NCT03721393",
      "title": "Data Collection - Of Syncope Tilt Table Testing Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Orthostatic Hypotension",
        "Reflex Syncope"
      ],
      "interventions": [
        {
          "name": "Wearable heart monitor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2019-10-04",
      "completion_date": "2023-05-08",
      "has_results": false,
      "last_update_posted_date": "2023-08-02",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03721393"
    },
    {
      "nct_id": "NCT01791816",
      "title": "Mechanisms of Vasovagal Syncope",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Vasovagal Syncope",
        "Postural Tachycardia Syndrome"
      ],
      "interventions": [
        {
          "name": "Phenylephrine",
          "type": "DRUG"
        },
        {
          "name": "L-Ng-monomethyl Arginine (L-NMMA)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "29 Years",
        "sex": "ALL",
        "summary": "14 Years to 29 Years"
      },
      "enrollment_count": 90,
      "start_date": "2013-02",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 1,
      "location_summary": "Hawthorne, New York",
      "locations": [
        {
          "city": "Hawthorne",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01791816"
    },
    {
      "nct_id": "NCT05270499",
      "title": "Aveir VR Real-World Evidence Post-Approval Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiac Pacemaker",
        "Arrythmia",
        "Bradycardia"
      ],
      "interventions": [
        {
          "name": "Aveir VR Leadless Pacemaker System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3427,
      "start_date": "2022-06-21",
      "completion_date": "2034-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 1,
      "location_summary": "Sylmar, California",
      "locations": [
        {
          "city": "Sylmar",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05270499"
    },
    {
      "nct_id": "NCT05935007",
      "title": "Aveir DR Real-World Evidence Post-Approval Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiac Pacemaker",
        "Arrythmia",
        "Bradycardia"
      ],
      "interventions": [
        {
          "name": "Aveir DR Leadless Pacemaker System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1805,
      "start_date": "2023-10-31",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 1,
      "location_summary": "Sylmar, California",
      "locations": [
        {
          "city": "Sylmar",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05935007"
    },
    {
      "nct_id": "NCT01456481",
      "title": "Assessment of Midodrine in the Prevention of Vasovagal Syncope: The Prevention of Syncope Trial IV",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Vasovagal Syncope"
      ],
      "interventions": [
        {
          "name": "midodrine hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "matching placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Dr. Bob Sheldon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 134,
      "start_date": "2011-11",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-05-09",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 2,
      "location_summary": "Minneapolis, Minnesota • Nashville, Tennessee",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01456481"
    },
    {
      "nct_id": "NCT00004479",
      "title": "Randomized Study of Midodrine, an Alpha Adrenergic Agonist, in Patients With Neurally Mediated Syncope",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Syncope"
      ],
      "interventions": [
        {
          "name": "midodrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": null,
      "start_date": "1999-03",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00004479"
    },
    {
      "nct_id": "NCT07502599",
      "title": "Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Orthostatic Hypotension",
        "Reflex Syncope"
      ],
      "interventions": [
        {
          "name": "Wearable holter monitor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2026-06",
      "completion_date": "2028-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-14",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07502599"
    },
    {
      "nct_id": "NCT03835299",
      "title": "Addressing Fear and Risk of Vasovagal Reactions Among High School Donors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blood Donors"
      ],
      "interventions": [
        {
          "name": "Fear Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 4035,
      "start_date": "2019-02-15",
      "completion_date": "2020-01-15",
      "has_results": false,
      "last_update_posted_date": "2021-09-16",
      "last_synced_at": "2026-05-22T06:44:33.051Z",
      "location_count": 1,
      "location_summary": "Athens, Ohio",
      "locations": [
        {
          "city": "Athens",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03835299"
    }
  ]
}