{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Refractory+Infantile+Spasms",
    "query": {
      "condition": "Refractory Infantile Spasms"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T09:12:11.304Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04086992",
      "title": "Decreasing Parental Stress of Caregivers of Infants With Infantile Spasms by Using Telemedicine Technology",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infantile Spasms, Non-Intractable"
      ],
      "interventions": [
        {
          "name": "Remote monitoring",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "31 Days",
        "maximum_age": "30 Months",
        "sex": "ALL",
        "summary": "31 Days to 30 Months"
      },
      "enrollment_count": 40,
      "start_date": "2019-10-10",
      "completion_date": "2023-10-30",
      "has_results": false,
      "last_update_posted_date": "2022-05-04",
      "last_synced_at": "2026-07-23T09:12:11.304Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04086992"
    },
    {
      "nct_id": "NCT03976076",
      "title": "A Study of Orally Administered JBPOS0101 in Refractory Infantile Spasms Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Refractory Infantile Spasms"
      ],
      "interventions": [
        {
          "name": "JBPOS0101",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bio-Pharm Solutions Co., Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "36 Months",
        "sex": "ALL",
        "summary": "6 Months to 36 Months"
      },
      "enrollment_count": 16,
      "start_date": "2020-04-15",
      "completion_date": "2021-12-10",
      "has_results": true,
      "last_update_posted_date": "2024-08-22",
      "last_synced_at": "2026-07-23T09:12:11.304Z",
      "location_count": 17,
      "location_summary": "Little Rock, Arkansas • Los Angeles, California • San Francisco, California + 13 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03976076"
    },
    {
      "nct_id": "NCT04289467",
      "title": "Treatment of Refractory Infantile Spasms With Fenfluramine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Infantile Spasm"
      ],
      "interventions": [
        {
          "name": "Fenfluramine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital of Orange County",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "36 Months",
        "sex": "ALL",
        "summary": "12 Months to 36 Months"
      },
      "enrollment_count": 10,
      "start_date": "2023-06-16",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-07-23T09:12:11.304Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Orange, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04289467"
    },
    {
      "nct_id": "NCT06700811",
      "title": "Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Developmental and Epileptic Encephalopathies",
        "Epileptic Spasms",
        "Genetic Epilepsy",
        "Neonatal and Infant Epilepsy"
      ],
      "interventions": [
        {
          "name": "Ketogenic diet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Heather Olson",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "9 Months",
        "sex": "ALL",
        "summary": "0 Days to 9 Months"
      },
      "enrollment_count": 10,
      "start_date": "2025-08-11",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-07-23T09:12:11.304Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06700811"
    },
    {
      "nct_id": "NCT05064878",
      "title": "A Phase 3 Study to Examine the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder.",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "CDKL5 Deficiency Disorder",
        "Generalized Tonic Clonic Seizure",
        "Epileptic Spasm",
        "Refractory Seizures"
      ],
      "interventions": [
        {
          "name": "Fenfluramine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Zogenix, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "1 Year to 35 Years"
      },
      "enrollment_count": 87,
      "start_date": "2022-03-08",
      "completion_date": "2027-11-08",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-07-23T09:12:11.304Z",
      "location_count": 13,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • San Francisco, California + 10 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05064878"
    },
    {
      "nct_id": "NCT02551731",
      "title": "Cannabidiol Oral Solution for Treatment of Refractory Infantile Spasms",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Spasms, Infantile"
      ],
      "interventions": [
        {
          "name": "Cannabidiol Oral Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "INSYS Therapeutics Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "36 Months",
        "sex": "ALL",
        "summary": "6 Months to 36 Months"
      },
      "enrollment_count": 9,
      "start_date": "2016-01-27",
      "completion_date": "2016-09-06",
      "has_results": true,
      "last_update_posted_date": "2018-09-19",
      "last_synced_at": "2026-07-23T09:12:11.304Z",
      "location_count": 4,
      "location_summary": "Los Angeles, California • San Francisco, California • Miami, Florida + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02551731"
    }
  ]
}