{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Remodeling%2C+Cardiac&page=2", "query": { "condition": "Remodeling, Cardiac", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Remodeling%2C+Cardiac&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-05-22T07:50:25.548Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00980031", "title": "Aldosterone Blockade to Prevent Myocardial Remodeling In Patients With Controlled Essential Hypertension", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Myocardial Remodeling" ], "interventions": [ { "name": "Eplerenone", "type": "DRUG" }, { "name": "Lactose Tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Creighton University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 20, "start_date": "2007-04", "completion_date": "2011-09", "has_results": false, "last_update_posted_date": "2014-03-28", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 1, "location_summary": "Omaha, Nebraska", "locations": [ { "city": "Omaha", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT00980031" }, { "nct_id": "NCT06770062", "title": "Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Left Ventricular Systolic Dysfunction" ], "interventions": [ { "name": "Cardiac MRI", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2025-01-20", "completion_date": "2027-12", "has_results": false, "last_update_posted_date": "2026-03-03", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT06770062" }, { "nct_id": "NCT02973633", "title": "Diffusion MRI in Heart Failure", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Heart Failure", "Myocardial Infarction", "Left Ventricular Hypertrophy" ], "interventions": [ { "name": "Diffusion Tensor MRI (DTI)", "type": "DEVICE" }, { "name": "Gadolinium DOTA Meglumine", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 160, "start_date": "2017-06-30", "completion_date": "2028-12-31", "has_results": false, "last_update_posted_date": "2025-12-24", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 1, "location_summary": "Charlestown, Massachusetts", "locations": [ { "city": "Charlestown", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02973633" }, { "nct_id": "NCT06150560", "title": "A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Coarctation of Aorta", "High Blood Pressure" ], "interventions": [ { "name": "Losartan", "type": "DRUG" }, { "name": "Amlodipine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 120, "start_date": "2024-04-01", "completion_date": "2028-06-01", "has_results": false, "last_update_posted_date": "2025-08-03", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT06150560" }, { "nct_id": "NCT01275339", "title": "Aortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot Study", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Aortic Stenosis", "LV Remodeling, Hypertrophy" ], "interventions": [ { "name": "Tadalafil", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2012-12", "completion_date": "2017-04-14", "has_results": true, "last_update_posted_date": "2019-04-17", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT01275339" }, { "nct_id": "NCT00785564", "title": "Imaging Cardiac Electrical Remodeling With Electrocardiogram Imaging (ECGI)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Sick Sinus Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 13, "start_date": "2007-11", "completion_date": "2011-09", "has_results": false, "last_update_posted_date": "2019-01-08", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT00785564" }, { "nct_id": "NCT06763549", "title": "COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cardiopulmonary Failure", "Myocardial Infarction (MI)", "Heart Decompensation", "Heart Failure", "HFrEF - Heart Failure with Reduced Ejection Fraction", "HFpEF - Heart Failure with Preserved Ejection Fraction", "Syncopation", "Syncope", "Ischemic Cardiovascular Disease", "STEMI", "STEMI (ST Elevation MI)", "Atrial Fibrillation (AF)", "Atrial Enlargement", "LVF", "Conduction Defect", "Conduction Abnormalities", "Heart Block", "Valvular Diseases", "Cardiac Output, Low", "Stroke Volume", "Stroke Volume Variation", "Hyperkalemia", "Hypercalcemia", "Hypocalcemia", "LV Dysfunction", "QT Prolongation", "Sudden Cardiac Death Due to Cardiac Arrhythmia", "Ventricular Arrhythmia", "Pacing", "Pacing Induced Dyssynchrony", "Silent Ischemia", "Pericarditis", "Sleep Related Breathing Disorder", "RSA", "Apnea, Obstructive", "Cardiac Output Measurement", "Respiratory Impedance", "CRT And/or ICD", "Infarction", "Cardiomyopathies, Primary", "Hypertrophy" ], "interventions": [ { "name": "SUBPROTOCOL A", "type": "DEVICE" }, { "name": "SUBPROTOCOL B", "type": "DEVICE" }, { "name": "SUBPROTOCOL C", "type": "DEVICE" }, { "name": "SUBPROTOCOL D", "type": "DEVICE" }, { "name": "SUBPROTOCOL E", "type": "DEVICE" }, { "name": "SUBPROTOCOL F", "type": "DEVICE" }, { "name": "SUBPROTOCOL G", "type": "DEVICE" }, { "name": "SUBPROTOCOL H", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Peerbridge Health, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15000, "start_date": "2024-11-16", "completion_date": "2026-04-15", "has_results": false, "last_update_posted_date": "2025-01-08", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 1, "location_summary": "Melbourne, Florida", "locations": [ { "city": "Melbourne", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06763549" }, { "nct_id": "NCT05600725", "title": "Novel Cardiac Pacing to Initiate Cardiac Remodeling in Heart Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cardiomyopathies", "Heart Rate", "Conditioning" ], "interventions": [ { "name": "novel atrial pacing approach", "type": "OTHER" }, { "name": "sham pacing approach", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Denise Hodgson-Zingman", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 5, "start_date": "2022-11-02", "completion_date": "2023-02-28", "has_results": false, "last_update_posted_date": "2023-05-16", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT05600725" }, { "nct_id": "NCT02924363", "title": "Effect of MitraClip on Acute and Chronic Reverse Cardiac Remodeling Assessed by CMR: The MITRA-REVERSE Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Mitral Regurgitation" ], "interventions": [ { "name": "Cardiac MRI with or without contrast dye", "type": "DIAGNOSTIC_TEST" }, { "name": "Blood sample", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Dipan Shah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 54, "start_date": "2017-01", "completion_date": "2021-12", "has_results": false, "last_update_posted_date": "2026-04-20", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 2, "location_summary": "Atlanta, Georgia • Houston, Texas", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02924363" }, { "nct_id": "NCT00043836", "title": "The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Heart Failure, Congestive", "Dyspnea", "Pulmonary Edema" ], "interventions": [ { "name": "ALT-711", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Synvista Therapeutics, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 20, "start_date": "2002-07", "completion_date": "2005-10", "has_results": false, "last_update_posted_date": "2009-09-02", "last_synced_at": "2026-05-22T07:50:25.548Z", "location_count": 2, "location_summary": "Winston-Salem, North Carolina • Charleston, South Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" }, { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00043836" } ] }