{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Respiration+Variability+Effect+on+Nervous+System",
    "query": {
      "condition": "Respiration Variability Effect on Nervous System"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T14:53:23.815Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04712656",
      "title": "Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sleep Apnea, Obstructive"
      ],
      "interventions": [
        {
          "name": "CPAP therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "30 Years to 75 Years"
      },
      "enrollment_count": 1739,
      "start_date": "2021-03-22",
      "completion_date": "2032-03-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-07-22T14:53:23.815Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04712656"
    },
    {
      "nct_id": "NCT04592718",
      "title": "Four-week Breathing Interventions on Gut Symptoms, Heart Rate Variability, and Psychological Measures in Runners",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastrointestinal System--Abnormalities",
        "Anxiety",
        "Visceral Pain"
      ],
      "interventions": [
        {
          "name": "Slow deep breathing plus breath counting",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Normal-paced breathing plus breath counting",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Old Dominion University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 63,
      "start_date": "2020-10-20",
      "completion_date": "2021-06-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-09",
      "last_synced_at": "2026-07-22T14:53:23.815Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04592718"
    },
    {
      "nct_id": "NCT00289666",
      "title": "The Effect of Positive Airway Pressure on Heart Rate Variability",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Christiana Care Health Services",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 38,
      "start_date": "2003-07",
      "completion_date": "2008-09",
      "has_results": false,
      "last_update_posted_date": "2016-07-11",
      "last_synced_at": "2026-07-22T14:53:23.815Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00289666"
    },
    {
      "nct_id": "NCT03280589",
      "title": "Pranayama Practice on the Autonomic Nervous System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pranayama Effect on Autonomic Nervous System",
        "Respiration Variability Effect on Nervous System"
      ],
      "interventions": [
        {
          "name": "Sheetali/Sheekari Pranayama",
          "type": "OTHER"
        },
        {
          "name": "Sitting Quietly",
          "type": "OTHER"
        },
        {
          "name": "Deep breathing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "National University of Natural Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "25 Years to 55 Years"
      },
      "enrollment_count": 25,
      "start_date": "2017-08-15",
      "completion_date": "2021-07-21",
      "has_results": false,
      "last_update_posted_date": "2023-03-24",
      "last_synced_at": "2026-07-22T14:53:23.815Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03280589"
    },
    {
      "nct_id": "NCT05480618",
      "title": "Slow Yogic-Derived Breathing and Respiration and Cardiovascular Variability in Spinal Cord Injury Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Slow Breathing"
      ],
      "interventions": [
        {
          "name": "Slow Breathing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 17,
      "start_date": "2022-08-22",
      "completion_date": "2024-01-20",
      "has_results": true,
      "last_update_posted_date": "2026-05-29",
      "last_synced_at": "2026-07-22T14:53:23.815Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05480618"
    }
  ]
}