{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Respiratory+Distress+of+Newborn&page=4",
    "query": {
      "condition": "Respiratory Distress of Newborn",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 422,
    "total_pages": 43,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Respiratory+Distress+of+Newborn&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Respiratory+Distress+of+Newborn&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T22:27:14.366Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01225029",
      "title": "Fluid Management in Transient Tachypnea of the Newborn",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Transient Tachypnea of the Newborn"
      ],
      "interventions": [
        {
          "name": "Amount of total fluids",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "Up to 24 Hours"
      },
      "enrollment_count": 64,
      "start_date": "2008-06",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2013-11-28",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01225029"
    },
    {
      "nct_id": "NCT00142376",
      "title": "Short Term Outcomes of Children With Acute Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Respiratory Distress Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "0 Years to 18 Years"
      },
      "enrollment_count": null,
      "start_date": "2004-09",
      "completion_date": "2005-08",
      "has_results": false,
      "last_update_posted_date": "2005-09-02",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00142376"
    },
    {
      "nct_id": "NCT05388708",
      "title": "ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Respiratory Distress Syndrome",
        "Extracorporeal Membrane Oxygenation"
      ],
      "interventions": [
        {
          "name": "ECMO support",
          "type": "DEVICE"
        },
        {
          "name": "PROSpect protocolized therapies",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Days",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "14 Days to 20 Years"
      },
      "enrollment_count": 550,
      "start_date": "2021-02-04",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-14",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 72,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 62 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05388708"
    },
    {
      "nct_id": "NCT00014859",
      "title": "Epidemiology of Surfactant Protein-B Deficiency",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lung Diseases",
        "Respiratory Distress Syndrome, Newborn",
        "Pulmonary Surfactant",
        "Lung Diseases, Interstitial"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 5176,
      "start_date": "2001-06-01",
      "completion_date": "2024-04-26",
      "has_results": false,
      "last_update_posted_date": "2024-04-29",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00014859"
    },
    {
      "nct_id": "NCT04334148",
      "title": "Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "Hydroxychloroquine",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Adrian Hernandez",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1360,
      "start_date": "2020-04-22",
      "completion_date": "2021-01-09",
      "has_results": true,
      "last_update_posted_date": "2021-10-12",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 34,
      "location_summary": "Aurora, Colorado • Gainesville, Florida • Jacksonville, Florida + 27 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Leesburg",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04334148"
    },
    {
      "nct_id": "NCT00244101",
      "title": "Delivery Room Management Trial of Premature Infants at High Risk of Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Newborn"
      ],
      "interventions": [
        {
          "name": "PS Group",
          "type": "DRUG"
        },
        {
          "name": "NCPAP Group",
          "type": "DEVICE"
        },
        {
          "name": "ISX Group",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Vermont Oxford Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "26 Weeks",
        "maximum_age": "29 Weeks",
        "sex": "ALL",
        "summary": "26 Weeks to 29 Weeks"
      },
      "enrollment_count": 648,
      "start_date": "2003-08",
      "completion_date": "2011-06",
      "has_results": true,
      "last_update_posted_date": "2023-01-18",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00244101"
    },
    {
      "nct_id": "NCT00399581",
      "title": "Comparison of Two Methods of High Frequency Oscillatory Ventilation in Individuals With Acute Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Respiratory Distress Syndrome, Adult"
      ],
      "interventions": [
        {
          "name": "High Frequency Oscillatory Ventilation-Hi",
          "type": "PROCEDURE"
        },
        {
          "name": "High Frequency Oscillatory Ventilation-Lo",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2006-11",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2013-02-27",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 5,
      "location_summary": "Baltimore, Maryland • Columbus, Ohio • San Antonio, Texas",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00399581"
    },
    {
      "nct_id": "NCT02871102",
      "title": "Stress Index to Individualize Mechanical Ventilation in ARDS",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Recruitment Maneuver with PEEP and Tidal Volume Optimization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2016-08",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-06-07",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02871102"
    },
    {
      "nct_id": "NCT06776783",
      "title": "Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Distress Syndrome",
        "Pre-term Infants"
      ],
      "interventions": [
        {
          "name": "APC-0101 (SF-RI 1 surfactant for inhalation combined with a dedicated delivery system)",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "OTHER"
      ],
      "sponsor": "Aerogen Pharma Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 24 Hours"
      },
      "enrollment_count": 520,
      "start_date": "2025-09-24",
      "completion_date": "2029-05",
      "has_results": false,
      "last_update_posted_date": "2026-08-06",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 12,
      "location_summary": "Little Rock, Arkansas • La Jolla, California • Jacksonville, Florida + 9 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "South Bend",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06776783"
    },
    {
      "nct_id": "NCT04493242",
      "title": "Extracellular Vesicle Infusion Treatment for COVID-19 Associated ARDS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "COVID-19",
        "ARDS"
      ],
      "interventions": [
        {
          "name": "ExoFlo",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Intravenous normal saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Direct Biologics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 102,
      "start_date": "2020-09-24",
      "completion_date": "2021-05-22",
      "has_results": true,
      "last_update_posted_date": "2024-02-13",
      "last_synced_at": "2026-10-06T22:27:14.366Z",
      "location_count": 6,
      "location_summary": "Sheffield, Alabama • Anaheim, California • Sayre, Pennsylvania + 3 more",
      "locations": [
        {
          "city": "Sheffield",
          "state": "Alabama"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Sayre",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04493242"
    }
  ]
}