{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Respiratory+Failure%2C+ICU&page=2",
    "query": {
      "condition": "Respiratory Failure, ICU",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Respiratory+Failure%2C+ICU&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T04:35:13.928Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07225257",
      "title": "Recovery of Physical Function After Critical Illness In Older Adults",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sepsis",
        "Acute Lung Injury(ALI)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Kentucky",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 150,
      "start_date": "2026-03-11",
      "completion_date": "2031-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-28",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07225257"
    },
    {
      "nct_id": "NCT02377830",
      "title": "CYCLE Pilot Randomized Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Intensive Care Unit Acquired Weakness",
        "Critical Care",
        "Mechanical Ventilation",
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "In-bed cycle ergometer (Restorative Therapies RT300 Supine)",
          "type": "DEVICE"
        },
        {
          "name": "Routine physiotherapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "McMaster University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 113,
      "start_date": "2015-03",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2022-12-05",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02377830"
    },
    {
      "nct_id": "NCT04582149",
      "title": "Eye-Control Trial: Wearable Eye-Tracking Device as Means of Communication",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure Requiring Mechanical Ventilation"
      ],
      "interventions": [
        {
          "name": "EyeControl Eye-tracking Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2021-05-19",
      "completion_date": "2023-01-23",
      "has_results": true,
      "last_update_posted_date": "2025-09-25",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04582149"
    },
    {
      "nct_id": "NCT06832306",
      "title": "STimulation to Activate RespIration",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ARDS (Moderate or Severe)",
        "AHRF",
        "Mechanically Ventilated ICU Patients"
      ],
      "interventions": [
        {
          "name": "Phrenic Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Lungpacer Medical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-05-28",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 6,
      "location_summary": "La Jolla, California • Shreveport, Louisiana • Winston-Salem, North Carolina + 3 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06832306"
    },
    {
      "nct_id": "NCT01270269",
      "title": "ACT-ICU Study: Activity and Cognitive Therapy in the Intensive Care Unit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Injuries",
        "Dementia",
        "Myopathies",
        "Muscle Disorders"
      ],
      "interventions": [
        {
          "name": "Behavioral: Physical and functional rehabilitation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral: Cognitive, physical, & functional rehabilitation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 87,
      "start_date": "2011-02",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2017-03-03",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01270269"
    },
    {
      "nct_id": "NCT01707303",
      "title": "Effect Of Acute Inflammatory Mediators On Functional Limitations In Patients With Acute Respiratory Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Early ICU rehabilitation strategies",
          "type": "OTHER"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2007-07",
      "completion_date": "2009-08",
      "has_results": false,
      "last_update_posted_date": "2018-08-15",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01707303"
    },
    {
      "nct_id": "NCT03471247",
      "title": "CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intensive Care Unit Acquired Weakness",
        "Critical Care",
        "Mechanical Ventilation",
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "In-Bed Cycle Ergometer",
          "type": "DEVICE"
        },
        {
          "name": "Routine PT",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "McMaster University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 360,
      "start_date": "2018-10-15",
      "completion_date": "2024-08",
      "has_results": false,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland • Durham, North Carolina",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03471247"
    },
    {
      "nct_id": "NCT03021902",
      "title": "Nutrition and Exercise in Critical Illness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "IV amino acids",
          "type": "DRUG"
        },
        {
          "name": "In-bed cycle ergometry exercise",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Clinical Evaluation Research Unit at Kingston General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 115,
      "start_date": "2017-09-28",
      "completion_date": "2025-06-23",
      "has_results": false,
      "last_update_posted_date": "2025-08-27",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 7,
      "location_summary": "Lexington, Kentucky • Baltimore, Maryland • The Bronx, New York + 4 more",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03021902"
    },
    {
      "nct_id": "NCT04379544",
      "title": "Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronavirus",
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "Observation only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 125,
      "start_date": "2020-04-23",
      "completion_date": "2021-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-09-21",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04379544"
    },
    {
      "nct_id": "NCT06538376",
      "title": "Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Edema",
        "Pneumonia",
        "Atelectasis",
        "Pleural Effusion",
        "Acute Rejection of Lung Transplant (Disorder)",
        "Airway Obstruction",
        "Rib Fractures",
        "Acute Copd Exacerbation",
        "Asthma COPD",
        "Pulmonary Embolism",
        "Hemothorax",
        "Pneumothorax",
        "Mesothelioma",
        "Diaphragmatic Paralysis"
      ],
      "interventions": [
        {
          "name": "Portable Dynamic Digital Radiography (DDR)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 230,
      "start_date": "2023-12-12",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2025-10-29",
      "last_synced_at": "2026-07-22T04:35:13.928Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06538376"
    }
  ]
}