{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Retinopathy+of+Prematurity&page=2",
    "query": {
      "condition": "Retinopathy of Prematurity",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Retinopathy+of+Prematurity&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T11:55:36.676Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01993043",
      "title": "39946-I Laser and Bevacizumab Treatment for Retinopathy of Prematurity",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "ROP Threshold"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Weeks",
        "maximum_age": "40 Weeks",
        "sex": "ALL",
        "summary": "30 Weeks to 40 Weeks"
      },
      "enrollment_count": 150,
      "start_date": "2010-10",
      "completion_date": "2023-09-12",
      "has_results": false,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 2,
      "location_summary": "Houston, Texas • Lubbock, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01993043"
    },
    {
      "nct_id": "NCT04515524",
      "title": "Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Non-Interventional",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Regeneron Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Months",
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "11 Months to 5 Years"
      },
      "enrollment_count": 100,
      "start_date": "2021-02-05",
      "completion_date": "2026-11-05",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 9,
      "location_summary": "La Jolla, California • Loma Linda, California • San Francisco, California + 5 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04515524"
    },
    {
      "nct_id": "NCT04519060",
      "title": "Eye Shields for Infants After Dilated Exam",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Newborn, Disease",
        "Pain",
        "Retinopathy of Prematurity",
        "Eye Diseases"
      ],
      "interventions": [
        {
          "name": "phototherapy eye shield",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 106,
      "start_date": "2021-02-01",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2021-03-12",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04519060"
    },
    {
      "nct_id": "NCT02386839",
      "title": "Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Retinopathy of Prematurity (ROP)"
      ],
      "interventions": [
        {
          "name": "rhIGF-1/rhIGFBP-3",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Shire",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Weeks",
        "maximum_age": "108 Weeks",
        "sex": "ALL",
        "summary": "40 Weeks to 108 Weeks"
      },
      "enrollment_count": 76,
      "start_date": "2015-03-26",
      "completion_date": "2021-09-28",
      "has_results": true,
      "last_update_posted_date": "2022-05-18",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 4,
      "location_summary": "Mobile, Alabama • Greenville, North Carolina • Oklahoma City, Oklahoma + 1 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Greenville",
          "state": "North Carolina"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02386839"
    },
    {
      "nct_id": "NCT04634604",
      "title": "A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Bevacizumab",
          "type": "DRUG"
        },
        {
          "name": "Laser",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 16,
      "start_date": "2022-04-27",
      "completion_date": "2023-08-14",
      "has_results": true,
      "last_update_posted_date": "2024-08-01",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 32,
      "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Irvine, California + 26 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04634604"
    },
    {
      "nct_id": "NCT02486042",
      "title": "Omega-3 Long Chain Polyunsaturated Fatty Acid (LCPUFA) Supplementation in Very Low Birth Weight Infants for The Prevention Retinopathy of Prematurity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        },
        {
          "name": "Standard lipids (primarily omega-6 fatty acids)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "7 Days",
        "sex": "ALL",
        "summary": "Up to 7 Days"
      },
      "enrollment_count": 48,
      "start_date": "2014-03",
      "completion_date": "2019-12",
      "has_results": true,
      "last_update_posted_date": "2022-12-29",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02486042"
    },
    {
      "nct_id": "NCT00233324",
      "title": "Surfactant Positive Airway Pressure and Pulse Oximetry Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Infant, Newborn, Diseases",
        "Other Preterm Infants",
        "Infant, Small for Gestational Age",
        "Premature Birth",
        "Bronchopulmonary Dysplasia",
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Surfactant",
          "type": "DRUG"
        },
        {
          "name": "Continuous Positive Airway Pressure (CPAP)",
          "type": "DEVICE"
        },
        {
          "name": "Supplemental oxygen with target saturation of 85 to 89%",
          "type": "DRUG"
        },
        {
          "name": "Supplemental oxygen with target saturation of 91 to 95%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "24 Weeks",
        "maximum_age": "27 Weeks",
        "sex": "ALL",
        "summary": "24 Weeks to 27 Weeks"
      },
      "enrollment_count": 1316,
      "start_date": "2005-02",
      "completion_date": "2016-08",
      "has_results": true,
      "last_update_posted_date": "2019-04-18",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 22,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • San Diego, California + 18 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00233324"
    },
    {
      "nct_id": "NCT00027222",
      "title": "The Early Treatment for Retinopathy of Prematurity Study (ETROP)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "retinal ablation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "42 Days",
        "sex": "ALL",
        "summary": "0 Years to 42 Days"
      },
      "enrollment_count": null,
      "start_date": "2001-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 26,
      "location_summary": "Palo Alto, California • San Francisco, California • Chicago, Illinois + 22 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00027222"
    },
    {
      "nct_id": "NCT04420156",
      "title": "Clinical and Genetic Analysis of ROP",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "No intervention administered.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 2000,
      "start_date": "2011-07-01",
      "completion_date": "2030-05-31",
      "has_results": false,
      "last_update_posted_date": "2022-04-20",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 5,
      "location_summary": "Palo Alto, California • Chicago, Illinois • Royal Oak, Michigan + 2 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04420156"
    },
    {
      "nct_id": "NCT00182390",
      "title": "Premature Infants in Need of Transfusion (PINT)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anemia of Prematurity"
      ],
      "interventions": [
        {
          "name": "Red blood cell transfusion",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "McMaster University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "48 Hours",
        "sex": "ALL",
        "summary": "Up to 48 Hours"
      },
      "enrollment_count": 424,
      "start_date": "2001-02",
      "completion_date": "2005-11",
      "has_results": false,
      "last_update_posted_date": "2015-09-24",
      "last_synced_at": "2026-06-10T11:55:36.676Z",
      "location_count": 2,
      "location_summary": "Albany, New York • Brooklyn, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00182390"
    }
  ]
}