{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Retinopathy+of+Prematurity+%28ROP%29",
    "query": {
      "condition": "Retinopathy of Prematurity (ROP)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 52,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Retinopathy+of+Prematurity+%28ROP%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T02:09:13.848Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04519060",
      "title": "Eye Shields for Infants After Dilated Exam",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Newborn, Disease",
        "Pain",
        "Retinopathy of Prematurity",
        "Eye Diseases"
      ],
      "interventions": [
        {
          "name": "phototherapy eye shield",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 106,
      "start_date": "2021-02-01",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2021-03-12",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04519060"
    },
    {
      "nct_id": "NCT02390531",
      "title": "Phase 1 Trial of Bevacizumab Treatment for Severe Retinopathy of Prematurity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Bevacizumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 120,
      "start_date": "2015-04-28",
      "completion_date": "2021-05-11",
      "has_results": true,
      "last_update_posted_date": "2022-11-03",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 11,
      "location_summary": "Atlanta, Georgia • Indianapolis, Indiana • Baltimore, Maryland + 8 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02390531"
    },
    {
      "nct_id": "NCT01054027",
      "title": "Study on Effective Mydriasis in Premature Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Retinopathy of Prematurity (ROP)"
      ],
      "interventions": [
        {
          "name": "1% phenylephrine and 0.2% cyclopentolate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 15,
      "start_date": "2007-03",
      "completion_date": "2008-03",
      "has_results": false,
      "last_update_posted_date": "2010-01-22",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01054027"
    },
    {
      "nct_id": "NCT00872664",
      "title": "Skin and Serum Carotenoids in Preterm Infants Fed on a Formula Supplemented With Carotenoids",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "carotenoids",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Days",
        "sex": "ALL",
        "summary": "Up to 21 Days"
      },
      "enrollment_count": 36,
      "start_date": "2009-09",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2013-12-04",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00872664"
    },
    {
      "nct_id": "NCT00000133",
      "title": "Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Trans-scleral Cryotherapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": null,
      "start_date": "1986-01",
      "completion_date": "2003-08",
      "has_results": false,
      "last_update_posted_date": "2014-02-04",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 24,
      "location_summary": "Birmingham, Alabama • Washington D.C., District of Columbia • Miami, Florida + 20 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00000133"
    },
    {
      "nct_id": "NCT02375971",
      "title": "RAINBOW Study: RAnibizumab Compared With Laser Therapy for the Treatment of INfants BOrn Prematurely With Retinopathy of Prematurity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Ranibizumab",
          "type": "DRUG"
        },
        {
          "name": "Laser therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 224,
      "start_date": "2015-12-30",
      "completion_date": "2017-12-14",
      "has_results": true,
      "last_update_posted_date": "2018-11-14",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 12,
      "location_summary": "Loma Linda, California • Sacramento, California • Aurora, Colorado + 9 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02375971"
    },
    {
      "nct_id": "NCT02887157",
      "title": "Analyzing Retinal Microanatomy in ROP",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinopathy of Prematurity",
        "Neurodevelopmental Disorders",
        "Macular Edema"
      ],
      "interventions": [
        {
          "name": "Swept Source OCT",
          "type": "DEVICE"
        },
        {
          "name": "Magnetic Resonance Imaging",
          "type": "OTHER"
        },
        {
          "name": "Scavenged blood collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Weeks and older"
      },
      "enrollment_count": 191,
      "start_date": "2016-07-22",
      "completion_date": "2021-04-15",
      "has_results": false,
      "last_update_posted_date": "2023-02-10",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 4,
      "location_summary": "Gainesville, Florida • St Louis, Missouri • Durham, North Carolina + 1 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02887157"
    },
    {
      "nct_id": "NCT01232777",
      "title": "Pan-VEGF Blockade for the Treatment of Retinopathy of Prematurity (BLOCK-ROP)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "Bevacizumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vision Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Weeks",
        "maximum_age": "36 Weeks",
        "sex": "ALL",
        "summary": "30 Weeks to 36 Weeks"
      },
      "enrollment_count": 0,
      "start_date": "2012-06",
      "completion_date": "2018-07",
      "has_results": false,
      "last_update_posted_date": "2013-10-17",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 18,
      "location_summary": "Los Angeles, California • Palo Alto, California • Miami, Florida + 14 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01232777"
    },
    {
      "nct_id": "NCT01264276",
      "title": "Telemedicine Approaches to Evaluating Acute-phase ROP",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "32 Weeks",
        "maximum_age": "40 Weeks",
        "sex": "ALL",
        "summary": "32 Weeks to 40 Weeks"
      },
      "enrollment_count": 269,
      "start_date": "2011-07",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2015-02-04",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 11,
      "location_summary": "Louisville, Kentucky • Baltimore, Maryland • Boston, Massachusetts + 8 more",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01264276"
    },
    {
      "nct_id": "NCT02257307",
      "title": "Telemedicine Approaches to Evaluating Acute-Phase ROP eROP Implementation Project",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinopathy of Prematurity"
      ],
      "interventions": [
        {
          "name": "RetCam retinal imaging used for routine care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "32 Weeks",
        "maximum_age": "40 Weeks",
        "sex": "ALL",
        "summary": "32 Weeks to 40 Weeks"
      },
      "enrollment_count": 244,
      "start_date": "2014-07",
      "completion_date": "2016-03-16",
      "has_results": false,
      "last_update_posted_date": "2017-04-13",
      "last_synced_at": "2026-06-11T02:09:13.848Z",
      "location_count": 5,
      "location_summary": "Baltimore, Maryland • Oklahoma City, Oklahoma • Philadelphia, Pennsylvania + 2 more",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02257307"
    }
  ]
}