{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Retinoschisis",
    "query": {
      "condition": "Retinoschisis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Retinoschisis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:19:47.922Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07502664",
      "title": "Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinitis Pigmentosa",
        "Stargardt Macular Dystrophy",
        "Stargardt Disease",
        "Geographic Atrophy From Age-related Macular Degeneration",
        "X-linked Retinoschisis",
        "Retinal Dystrophies"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ray Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2026-02-19",
      "completion_date": "2027-02",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07502664"
    },
    {
      "nct_id": "NCT02435940",
      "title": "Inherited Retinal Degenerative Disease Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Eye Diseases Hereditary",
        "Retinal Disease",
        "Achromatopsia",
        "Bardet-Biedl Syndrome",
        "Bassen-Kornzweig Syndrome",
        "Batten Disease",
        "Best Disease",
        "Choroidal Dystrophy",
        "Choroideremia",
        "Cone Dystrophy",
        "Cone-Rod Dystrophy",
        "Congenital Stationary Night Blindness",
        "Enhanced S-Cone Syndrome",
        "Fundus Albipunctatus",
        "Goldmann-Favre Syndrome",
        "Gyrate Atrophy",
        "Juvenile Macular Degeneration",
        "Kearns-Sayre Syndrome",
        "Leber Congenital Amaurosis",
        "Refsum Syndrome",
        "Retinitis Pigmentosa",
        "Retinitis Punctata Albescens",
        "Retinoschisis",
        "Rod-Cone Dystrophy",
        "Rod Dystrophy",
        "Rod Monochromacy",
        "Stargardt Disease",
        "Usher Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Foundation Fighting Blindness",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20000,
      "start_date": "2014-06",
      "completion_date": "2037-06",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 1,
      "location_summary": "Columbia, Maryland",
      "locations": [
        {
          "city": "Columbia",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02435940"
    },
    {
      "nct_id": "NCT02416622",
      "title": "Safety and Efficacy of rAAV-hRS1 in Patients With X-linked Retinoschisis (XLRS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "X-linked Retinoschisis"
      ],
      "interventions": [
        {
          "name": "rAAV2tYF-CB-hRS1",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Beacon Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "6 Years and older · Male only"
      },
      "enrollment_count": 27,
      "start_date": "2015-05",
      "completion_date": "2023-05-09",
      "has_results": true,
      "last_update_posted_date": "2023-06-12",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 9,
      "location_summary": "San Francisco, California • Miami, Florida • Baltimore, Maryland + 6 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02416622"
    },
    {
      "nct_id": "NCT01995045",
      "title": "Postoperative Pain Control Following Vitreoretinal Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Retinal Detachment",
        "Proliferative Vitreoretinopathy",
        "Retinoschisis"
      ],
      "interventions": [
        {
          "name": "Triamcinolone",
          "type": "DRUG"
        },
        {
          "name": "Bupivicaine Hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 58,
      "start_date": "2012-07",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2017-03-21",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01995045"
    },
    {
      "nct_id": "NCT02317887",
      "title": "Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Retinoschisis",
        "X-Linked"
      ],
      "interventions": [
        {
          "name": "RS1 AAV Vector",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "VegaVect, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 12,
      "start_date": "2015-02-11",
      "completion_date": "2024-10-16",
      "has_results": true,
      "last_update_posted_date": "2025-02-14",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02317887"
    },
    {
      "nct_id": "NCT00055029",
      "title": "Clinical and Genetic Studies of X-Linked Juvenile Retinoschisis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinoschisis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "9 Months",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "9 Months to 100 Years"
      },
      "enrollment_count": 351,
      "start_date": "2003-05-19",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-04-24",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • Rochester, Michigan",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Rochester",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00055029"
    },
    {
      "nct_id": "NCT02317354",
      "title": "People s Expectations When Enrolling in a Phase I/II RS1 Ocular Gene Transfer Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinoschisis",
        "X-Linked"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 13,
      "start_date": "2014-12-13",
      "completion_date": "2017-11-20",
      "has_results": false,
      "last_update_posted_date": "2019-12-09",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02317354"
    },
    {
      "nct_id": "NCT03354403",
      "title": "Mothers Experiences With X-linked Retinoschisis Compared to Fathers Experiences",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinoschisis",
        "X-Linked"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2017-12-01",
      "completion_date": "2019-10-30",
      "has_results": false,
      "last_update_posted_date": "2019-11-01",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03354403"
    },
    {
      "nct_id": "NCT05878860",
      "title": "ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "X-linked Retinoschisis"
      ],
      "interventions": [
        {
          "name": "ATSN-201",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Atsena Therapeutics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 97,
      "start_date": "2023-08-22",
      "completion_date": "2033-04",
      "has_results": false,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 4,
      "location_summary": "Los Angeles, California • Miami, Florida • Portland, Oregon + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05878860"
    },
    {
      "nct_id": "NCT02331173",
      "title": "Clinical Evaluation of Patients With X-linked Retinoschisis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "X-linked Retinoschisis",
        "XLRS"
      ],
      "interventions": [
        {
          "name": "Dorzolamide 2% TID or brinzolamide 1% TID",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Beacon Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "7 Years and older · Male only"
      },
      "enrollment_count": 66,
      "start_date": "2012-11",
      "completion_date": "2016-10",
      "has_results": false,
      "last_update_posted_date": "2017-11-17",
      "last_synced_at": "2026-05-22T04:19:47.922Z",
      "location_count": 3,
      "location_summary": "Ann Arbor, Michigan • Portland, Oregon • Dallas, Texas",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02331173"
    }
  ]
}