{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Rheumatic+Conditions", "query": { "condition": "Rheumatic Conditions" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 711, "total_pages": 72, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Rheumatic+Conditions&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-24T06:49:28.030Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00546598", "title": "Post-approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Non-inflammatory Joint Disease", "Osteoarthritis", "Avascular Necrosis", "Congenital Hip Dysplasia", "Post-traumatic Arthritis" ], "interventions": [ { "name": "Total hip replacement/arthroplasty", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "DePuy Orthopaedics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "21 Years to 80 Years" }, "enrollment_count": 106, "start_date": "2006-01-01", "completion_date": "2014-04-01", "has_results": false, "last_update_posted_date": "2021-11-30", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 6, "location_summary": "Atlanta, Georgia • Springfield, Illinois • Cleveland, Ohio + 2 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Springfield", "state": "Illinois" }, { "city": "Springfield", "state": "Illinois" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Maumee", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00546598" }, { "nct_id": "NCT05670236", "title": "Effect of Knee Pain on Walking Biomechanics", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Osteoarthritis, Knee" ], "interventions": [ { "name": "Lidocaine Hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "45 Years", "maximum_age": null, "sex": "ALL", "summary": "45 Years and older" }, "enrollment_count": 55, "start_date": "2023-01-25", "completion_date": "2024-07-19", "has_results": true, "last_update_posted_date": "2025-10-29", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05670236" }, { "nct_id": "NCT02829814", "title": "Repeat of: A Study to Evaluate Efficacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With Fibromyalgia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Fibromyalgia", "Myofascial Pain Syndromes", "Muscular Diseases", "Nervous System Diseases", "Neuromuscular Diseases", "Rheumatic Diseases", "Musculoskeletal Diseases" ], "interventions": [ { "name": "TNX-102 SL Tablet, 2.8 mg", "type": "DRUG" }, { "name": "Placebo SL Tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Tonix Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 51, "start_date": "2016-07-22", "completion_date": "2016-09-13", "has_results": true, "last_update_posted_date": "2025-02-25", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 32, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Oceanside, California + 28 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Oceanside", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Brandon", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02829814" }, { "nct_id": "NCT01142349", "title": "Cognitive Behavioral Therapy for Arthritis Pain and Insomnia in Older Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pain Dysfunction", "Sleep Disturbance", "Osteoarthritis" ], "interventions": [ { "name": "Lifestyles A", "type": "BEHAVIORAL" }, { "name": "Lifestyles B", "type": "BEHAVIORAL" }, { "name": "Lifestyles C", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 367, "start_date": "2009-01", "completion_date": "2013-08", "has_results": false, "last_update_posted_date": "2013-12-19", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 2, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01142349" }, { "nct_id": "NCT03840928", "title": "PatientSpot Formerly Known as ArthritisPower", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rheumatoid Arthritis", "Ankylosing Spondylitis", "Fibromyalgia", "Gout", "Crohn Disease", "Juvenile Idiopathic Arthritis", "Lupus Erythematosus", "Myositis", "Osteoarthritis", "Osteoporosis", "Psoriasis", "Psoriatic Arthritis", "Scleroderma", "Dermatomyositis", "Inflammatory Bowel Diseases", "Polymyositis", "Axial Spondyloarthritis", "Diffuse Idiopathic Skeletal Hyperostosis", "Polymyalgia Rheumatica", "Giant Cell Arteritis", "Temporal Arteritis", "Wegener", "Relapsing Polychondritis", "Undifferentiated Connective Tissue Disease", "Spinal Cord Injuries", "Alzheimer Disease", "Amyotrophic Lateral Sclerosis", "Ataxia", "Bell Palsy", "Brain Tumor", "Cerebral Aneurysm", "Epilepsy", "Guillain-Barre Syndrome", "Headache", "Head Injury", "Hydrocephalus", "Lumbar Disc Disease", "Meningitis", "Multiple Sclerosis", "Muscular Dystrophy", "Neurocutaneous Syndromes", "Parkinson Disease", "Stroke", "Cluster Headache", "Tension-Type Headache", "Chronic Obstructive Pulmonary Disease", "Asthma", "Lung Cancer", "Cystic Fibrosis", "Sleep Apnea", "Eczema", "Alopecia", "Chronic Inflammation", "Unstable Angina", "Heart Attack", "Heart Failure", "Arrythmia", "Valve Heart Disease", "High Blood Pressure", "Congenital Heart Disease", "Peripheral Arterial Disease", "Diabetes", "Chronic Liver Disease", "Obesity" ], "interventions": [], "intervention_types": [], "sponsor": "Global Healthy Living Foundation", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 40000, "start_date": "2015-04-01", "completion_date": "2025-03-01", "has_results": false, "last_update_posted_date": "2023-12-13", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 1, "location_summary": "Upper Nyack, New York", "locations": [ { "city": "Upper Nyack", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03840928" }, { "nct_id": "NCT04862871", "title": "Enhancing Analgesia in Chronic Pain Through Exercise", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pain", "Chronic Widespread Pain", "Fibromyalgia" ], "interventions": [ { "name": "Physical Activity - Pediatric Pain Rehabilitation Center", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Boston Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "10 Years", "maximum_age": "24 Years", "sex": "ALL", "summary": "10 Years to 24 Years" }, "enrollment_count": 30, "start_date": "2022-04-01", "completion_date": "2022-11", "has_results": false, "last_update_posted_date": "2022-05-11", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04862871" }, { "nct_id": "NCT05787821", "title": "Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Knee Pain Chronic", "Osteoarthritis, Knee", "Rheumatoid Arthritis", "Traumatic Arthritis", "Polyarthritis", "Varus Deformity", "Valgus Deformity", "Flexion Deformity of Knee", "Avascular Necrosis" ], "interventions": [ { "name": "Total Knee Arthroplasty", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Zimmer Biomet", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 760, "start_date": "2023-06-28", "completion_date": "2035-06", "has_results": false, "last_update_posted_date": "2026-07-10", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 16, "location_summary": "Parker, Colorado • Tampa, Florida • Atlanta, Georgia + 13 more", "locations": [ { "city": "Parker", "state": "Colorado" }, { "city": "Tampa", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT05787821" }, { "nct_id": "NCT03569020", "title": "The Diet Gout Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Gout", "Hyperuricemia" ], "interventions": [ { "name": "Subsidy for food purchases and dietitian education", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 43, "start_date": "2018-08-07", "completion_date": "2019-07-23", "has_results": true, "last_update_posted_date": "2021-03-30", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 2, "location_summary": "Woodlawn, Maryland • Boston, Massachusetts", "locations": [ { "city": "Woodlawn", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03569020" }, { "nct_id": "NCT00034060", "title": "The Role of Cytokines on Growth Hormone Suppression in Premenopausal Women With Rheumatoid Arthritis and the Effect of Treatment With Etanercept", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rheumatoid Arthritis", "Healthy" ], "interventions": [ { "name": "Etanercept", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "FEMALE", "summary": "Female only" }, "enrollment_count": 36, "start_date": "2002-04", "completion_date": "2005-12", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00034060" }, { "nct_id": "NCT02196818", "title": "A Multi-centre, Prospective Surveillance to Assess Mid-term Performance of the Mpact Cup", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Osteoarthritis", "Arthritis", "Avascular Necrosis", "Fracture of the Femoral Neck or Head", "Congenital Hip Dysplasia" ], "interventions": [ { "name": "Mpact Acetabular Shell", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medacta International SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 200, "start_date": "2013-03", "completion_date": "2022-04", "has_results": false, "last_update_posted_date": "2023-03-22", "last_synced_at": "2026-07-24T06:49:28.030Z", "location_count": 4, "location_summary": "Denver, Colorado • Boise, Idaho • Libertyville, Illinois + 1 more", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Boise", "state": "Idaho" }, { "city": "Libertyville", "state": "Illinois" }, { "city": "West Jordan", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT02196818" } ] }