{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Rheumatoid+Arthritis+of+Knee",
    "query": {
      "condition": "Rheumatoid Arthritis of Knee"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 37,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Rheumatoid+Arthritis+of+Knee&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T09:20:12.096Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03969654",
      "title": "ROSA Robot Used in Total Knee Replacement Post Market Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Pain",
        "Chronic Osteoarthritis",
        "Avascular Necrosis of the Femoral Condyle",
        "Moderate Varus, Valgus or Flexion Deformities",
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "PERSONA Total Knee",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard Total Knee",
          "type": "DEVICE"
        },
        {
          "name": "NexGen Total Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 181,
      "start_date": "2020-05-01",
      "completion_date": "2023-09-22",
      "has_results": true,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 5,
      "location_summary": "Vail, Colorado • Westminster, Colorado • Springfield, Illinois + 2 more",
      "locations": [
        {
          "city": "Vail",
          "state": "Colorado"
        },
        {
          "city": "Westminster",
          "state": "Colorado"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "North Chesterfield",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03969654"
    },
    {
      "nct_id": "NCT04301622",
      "title": "Post Market Clinical Follow-Up Study for EVOLUTION® BIOFOAM® Tibia and EVOLUTION® CS/CR Porous Femur",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Osteoarthritis",
        "Traumatic Arthritis of Knee",
        "Avascular Necrosis",
        "Degenerative Joint Disease of Knee",
        "Rheumatoid Arthritis of Knee",
        "Correction of Functional Deformity"
      ],
      "interventions": [
        {
          "name": "Primary Knee implants",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MicroPort Orthopedics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2020-02-03",
      "completion_date": "2032-08",
      "has_results": false,
      "last_update_posted_date": "2024-03-20",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 1,
      "location_summary": "Saginaw, Michigan",
      "locations": [
        {
          "city": "Saginaw",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04301622"
    },
    {
      "nct_id": "NCT02237911",
      "title": "Comparison of Treatments Following Total Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degeneration; Articular Cartilage, Knee",
        "Rheumatoid Arthritis",
        "Osteoarthritis, Knee"
      ],
      "interventions": [
        {
          "name": "Clinic-based outpatient exercise group",
          "type": "OTHER"
        },
        {
          "name": "Community-based exercise group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2014-12",
      "completion_date": "2017-09-07",
      "has_results": true,
      "last_update_posted_date": "2019-03-11",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02237911"
    },
    {
      "nct_id": "NCT05787821",
      "title": "Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Pain Chronic",
        "Osteoarthritis, Knee",
        "Rheumatoid Arthritis",
        "Traumatic Arthritis",
        "Polyarthritis",
        "Varus Deformity",
        "Valgus Deformity",
        "Flexion Deformity of Knee",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Total Knee Arthroplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 760,
      "start_date": "2023-06-28",
      "completion_date": "2035-06",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 16,
      "location_summary": "Parker, Colorado • Tampa, Florida • Atlanta, Georgia + 13 more",
      "locations": [
        {
          "city": "Parker",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05787821"
    },
    {
      "nct_id": "NCT06670651",
      "title": "LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis (OA) of the Knee",
        "Fracture",
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "total knee arthroplasty device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "LinkBio Corp.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 600,
      "start_date": "2025-03-21",
      "completion_date": "2031-12",
      "has_results": false,
      "last_update_posted_date": "2025-06-10",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Libertyville, Illinois",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Libertyville",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06670651"
    },
    {
      "nct_id": "NCT01542580",
      "title": "A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Traumatic Arthritis",
        "Post Traumatic Deformity",
        "Complications; Arthroplasty",
        "Deformity of Limb"
      ],
      "interventions": [
        {
          "name": "Vanguard SSK 360 with PS Bearing",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard SSK 360 with PSC bearing",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard DA 360",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard 360 TiNbN Femur with PS bearing",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard 360 TiNbN Femur with PSC bearing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 255,
      "start_date": "2012-03",
      "completion_date": "2031-12",
      "has_results": false,
      "last_update_posted_date": "2025-11-25",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 4,
      "location_summary": "Morton Grove, Illinois • Henderson, Nevada • Salt Lake City, Utah + 1 more",
      "locations": [
        {
          "city": "Morton Grove",
          "state": "Illinois"
        },
        {
          "city": "Henderson",
          "state": "Nevada"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01542580"
    },
    {
      "nct_id": "NCT00289094",
      "title": "Randomized Fixed Bearing vs Mobile Bearing Cruciate Retaining TKA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Post-traumatic Arthritis",
        "Juvenile Rheumatoid Arthritis",
        "Avascular Necrosis of Bone"
      ],
      "interventions": [
        {
          "name": "Total knee replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 99,
      "start_date": "2001-03-01",
      "completion_date": "2007-12-26",
      "has_results": true,
      "last_update_posted_date": "2022-09-13",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 2,
      "location_summary": "Billings, Montana • Vancouver, Washington",
      "locations": [
        {
          "city": "Billings",
          "state": "Montana"
        },
        {
          "city": "Vancouver",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00289094"
    },
    {
      "nct_id": "NCT07391592",
      "title": "Post Market Clinical Follow-Up Study for EVOLUTION® NitrX™ Keeled Tibia and EVOLUTION® NitrX™ CS/CR Femur With Cruciate Sacrificing Insert",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthitis",
        "Arthritis Knee",
        "Joint Diseases",
        "Avascular Necrosis",
        "Rheumatoid Arthritis of Knee"
      ],
      "interventions": [
        {
          "name": "EVOLUTION® NitrX™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MicroPort Orthopedics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2025-08-18",
      "completion_date": "2032-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 1,
      "location_summary": "Fremont, California",
      "locations": [
        {
          "city": "Fremont",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07391592"
    },
    {
      "nct_id": "NCT00819481",
      "title": "Post-Market Study of the 3DKnee™ System",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Joint Disease",
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Traumatic Arthritis"
      ],
      "interventions": [
        {
          "name": "3DKnee™ System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Encore Medical, L.P.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 229,
      "start_date": "2009-02",
      "completion_date": "2018-10",
      "has_results": false,
      "last_update_posted_date": "2021-03-16",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 8,
      "location_summary": "Scottsdale, Arizona • Fresno, California • Baltimore, Maryland + 5 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Silver Spring",
          "state": "Maryland"
        },
        {
          "city": "Camdenton",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00819481"
    },
    {
      "nct_id": "NCT00289081",
      "title": "Primary TKA Cruciate Retaining vs Cruciate Substituting With Rotating Platform Knee Prostheses",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Arthritis, Rheumatoid",
        "Avascular Necrosis of Bone",
        "Post-traumatic Arthritis",
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "Total knee replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 399,
      "start_date": "2001-02",
      "completion_date": "2006-06",
      "has_results": false,
      "last_update_posted_date": "2014-05-13",
      "last_synced_at": "2026-06-10T09:20:12.096Z",
      "location_count": 4,
      "location_summary": "La Jolla, California • Crystal River, Florida • Melbourne, Florida + 1 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Crystal River",
          "state": "Florida"
        },
        {
          "city": "Melbourne",
          "state": "Florida"
        },
        {
          "city": "Cleveland Heights",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00289081"
    }
  ]
}