{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Rheumatoid+and+Osteoarthritis",
    "query": {
      "condition": "Rheumatoid and Osteoarthritis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 137,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Rheumatoid+and+Osteoarthritis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T00:08:15.395Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00764959",
      "title": "Retrospective Study of the Linear™ Hip",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Femoral Fracture",
        "Correction of a Functional Deformity",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Encore Linear™ Hip System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Encore Medical, L.P.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2007-10",
      "completion_date": "2011-02",
      "has_results": false,
      "last_update_posted_date": "2011-02-09",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 1,
      "location_summary": "Vero Beach, Florida",
      "locations": [
        {
          "city": "Vero Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00764959"
    },
    {
      "nct_id": "NCT05787821",
      "title": "Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Pain Chronic",
        "Osteoarthritis, Knee",
        "Rheumatoid Arthritis",
        "Traumatic Arthritis",
        "Polyarthritis",
        "Varus Deformity",
        "Valgus Deformity",
        "Flexion Deformity of Knee",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Total Knee Arthroplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 760,
      "start_date": "2023-06-28",
      "completion_date": "2035-06",
      "has_results": false,
      "last_update_posted_date": "2026-07-10",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 16,
      "location_summary": "Parker, Colorado • Tampa, Florida • Atlanta, Georgia + 13 more",
      "locations": [
        {
          "city": "Parker",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05787821"
    },
    {
      "nct_id": "NCT04238143",
      "title": "Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Osteo Arthritis Knee",
        "Osteo Arthritis Shoulders",
        "Osteoarthritis of Multiple Joints",
        "Osteoarthritis, Hip",
        "Osteoarthritis - Ankle/Foot"
      ],
      "interventions": [
        {
          "name": "Tissue Stromal Vascular Fraction (tSVF) Arm 1",
          "type": "PROCEDURE"
        },
        {
          "name": "PRP Concentrate Arm 1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Tissue Stromal Vascular Fraction (tSVF) Arm 2",
          "type": "PROCEDURE"
        },
        {
          "name": "PRP Concentrate Arm 2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Cellular Stromal Vascular Fraction (cSVF) Arm 2",
          "type": "PROCEDURE"
        },
        {
          "name": "Cellular Stromal Vascular Fraction (cSVF) Arm 3",
          "type": "PROCEDURE"
        },
        {
          "name": "Sterile Normal Saline (IV Solution)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Healeon Medical Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 100,
      "start_date": "2020-01-10",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-10-01",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 2,
      "location_summary": "Valencia, California • Stevensville, Montana",
      "locations": [
        {
          "city": "Valencia",
          "state": "California"
        },
        {
          "city": "Stevensville",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04238143"
    },
    {
      "nct_id": "NCT05603728",
      "title": "Exactech Shoulder Post Market Clinical Follow-up Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteo Arthritis Shoulders",
        "Osteonecrosis",
        "Rotator Cuff Tears",
        "Rotator Cuff Tear Arthropathy",
        "Ankylosing Spondylitis",
        "Post-traumatic Osteoarthritis",
        "Rheumatoid Arthritis",
        "Fracture",
        "Infections"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Exactech",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 20000,
      "start_date": "2007-07-19",
      "completion_date": "2031-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-15",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 24,
      "location_summary": "Laguna Woods, California • Redwood City, California • Stockton, California + 19 more",
      "locations": [
        {
          "city": "Laguna Woods",
          "state": "California"
        },
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Stockton",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05603728"
    },
    {
      "nct_id": "NCT02038140",
      "title": "Zimmer Trabecular Metal Total Ankle PMCF",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Arthritis",
        "Rheumatoid Arthritis",
        "Post Traumatic Arthritis"
      ],
      "interventions": [
        {
          "name": "Zimmer Trabecular Metal Total Ankle System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2014-03",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 5,
      "location_summary": "Sacramento, California • Grand Rapids, Michigan • Charlotte, North Carolina + 2 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02038140"
    },
    {
      "nct_id": "NCT00398255",
      "title": "Healthier Living With Arthritis Online Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Fibromyalgia"
      ],
      "interventions": [
        {
          "name": "self-management program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 900,
      "start_date": "2004-02",
      "completion_date": "2006-12",
      "has_results": false,
      "last_update_posted_date": "2013-04-30",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00398255"
    },
    {
      "nct_id": "NCT05351060",
      "title": "Novel Splinting Technique Using 3D Models",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthritis",
        "Osteoarthritis Hand",
        "Scleroderma, Systemic",
        "Scleroderma, Diffuse",
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "Custom Fabricated Splint",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Giovanna Fichera",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 10,
      "start_date": "2022-05-16",
      "completion_date": "2022-08-19",
      "has_results": false,
      "last_update_posted_date": "2022-04-28",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 1,
      "location_summary": "Troy, New York",
      "locations": [
        {
          "city": "Troy",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05351060"
    },
    {
      "nct_id": "NCT01698762",
      "title": "IADAPT-Third Phase",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Musculoskeletal Diseases"
      ],
      "interventions": [
        {
          "name": "Multimedia Patient Decision Aids (MM-PtDAs)",
          "type": "OTHER"
        },
        {
          "name": "Comparative Effectiveness Research Summary Guide (CERSG)",
          "type": "OTHER"
        },
        {
          "name": "Questionnaires",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 676,
      "start_date": "2013-03-05",
      "completion_date": "2021-04-21",
      "has_results": false,
      "last_update_posted_date": "2021-05-26",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 3,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01698762"
    },
    {
      "nct_id": "NCT00455208",
      "title": "A Study Evaluating the Safety and Efficacy of Cura-100 in Subjects With Rheumatoid Arthritis and Osteoarthritis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Rheumatoid Arthritis",
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Cura-100",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cura Biotech LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 20,
      "start_date": "2007-05",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2009-02-19",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 1,
      "location_summary": "Sunnyvale, California",
      "locations": [
        {
          "city": "Sunnyvale",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00455208"
    },
    {
      "nct_id": "NCT05630053",
      "title": "Cemented vs Cementless Persona Keel RCT",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Pain Chronic",
        "Rheumatoid Arthritis",
        "Osteoarthritis",
        "Traumatic Arthritis",
        "Polyarthritis",
        "Avascular Necrosis",
        "Varus Deformity",
        "Valgus Deformity",
        "Flexion Deformity of Knee"
      ],
      "interventions": [
        {
          "name": "Cementless Persona Knee System",
          "type": "DEVICE"
        },
        {
          "name": "Cemented Persona Knee System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-07-25",
      "completion_date": "2032-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-27",
      "last_synced_at": "2026-07-23T00:08:15.395Z",
      "location_count": 7,
      "location_summary": "Westminster, Colorado • Chicago, Illinois • Baltimore, Maryland + 4 more",
      "locations": [
        {
          "city": "Westminster",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Bryn Mawr",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05630053"
    }
  ]
}