{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Risk-reducing+Surgery",
    "query": {
      "condition": "Risk-reducing Surgery"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 34,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Risk-reducing+Surgery&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T18:13:01.389Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07644819",
      "title": "Preoperative Outreach to Improve Surgical Attendance",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Urology"
      ],
      "interventions": [
        {
          "name": "Preoperative Outreach",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2026-06",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-12",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07644819"
    },
    {
      "nct_id": "NCT03261323",
      "title": "Breast Reconstruction Following Breast Cancer in Very High Risk Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Malignant Neoplasm of Breast"
      ],
      "interventions": [
        {
          "name": "Immediate Breast Reconstruction",
          "type": "PROCEDURE"
        },
        {
          "name": "Delayed Breast Reconstruction",
          "type": "PROCEDURE"
        },
        {
          "name": "Breast-Q questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Case Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "19 Years and older · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2019-05-31",
      "completion_date": "2022-07",
      "has_results": false,
      "last_update_posted_date": "2022-05-20",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03261323"
    },
    {
      "nct_id": "NCT04725916",
      "title": "Studying How Outpatient Water affEcts Risks With Drains (SHOWER Study)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Wound Infection",
        "Postoperative Complications",
        "Surgical Site Infection",
        "Drain Site Complication"
      ],
      "interventions": [
        {
          "name": "Showering",
          "type": "OTHER"
        },
        {
          "name": "Restriction of Showering",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Sean Devitt",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2022-02-23",
      "completion_date": "2027-07-15",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 1,
      "location_summary": "Danville, Pennsylvania",
      "locations": [
        {
          "city": "Danville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04725916"
    },
    {
      "nct_id": "NCT00281489",
      "title": "Study Evaluating Ways of Preventing Patients From Being Awake During High-Risk Surgery and Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Explicit Recall of Intra-operative Events"
      ],
      "interventions": [
        {
          "name": "BIS Monitor guided algorithm",
          "type": "DEVICE"
        },
        {
          "name": "Volatile anesthetic guided algorithm",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2005-08",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2012-07-23",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00281489"
    },
    {
      "nct_id": "NCT05441592",
      "title": "A Randomized Control Trial Assessing the Effect of Topical Tranexamic Acid on Risk of Hematoma in Breast Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hematoma Postoperative"
      ],
      "interventions": [
        {
          "name": "Tranexamic acid injection",
          "type": "DRUG"
        },
        {
          "name": "No additional irrigation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 107,
      "start_date": "2022-08-15",
      "completion_date": "2024-10-22",
      "has_results": true,
      "last_update_posted_date": "2025-11-26",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05441592"
    },
    {
      "nct_id": "NCT06862648",
      "title": "Evaluating SUI-100™, A Non-Invasive Device for the Treatment of Stress Urinary Incontinence",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Urinary Incontinence (SUI)"
      ],
      "interventions": [
        {
          "name": "Acoustic Stimulation Therapy Device",
          "type": "DEVICE"
        },
        {
          "name": "Sham Acoustic Stimulation Therapy Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Acoustic Wave Cell Therapy, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "77 Years",
        "sex": "FEMALE",
        "summary": "22 Years to 77 Years · Female only"
      },
      "enrollment_count": 130,
      "start_date": "2025-03-25",
      "completion_date": "2026-11-09",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 9,
      "location_summary": "Phoenix, Arizona • Lakeland, Florida • Boise, Idaho + 6 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Lakeland",
          "state": "Florida"
        },
        {
          "city": "Boise",
          "state": "Idaho"
        },
        {
          "city": "Meridian",
          "state": "Idaho"
        },
        {
          "city": "Wichita",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06862648"
    },
    {
      "nct_id": "NCT02158923",
      "title": "Individualized Perioperative Open Lung Ventilatory Strategy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Moderated-high Risk of Postoperative Pulmonary Complication",
        "Abdominal Surgery Expected More Than Two Hours"
      ],
      "interventions": [
        {
          "name": "Alveolar recruitment maneuver",
          "type": "PROCEDURE"
        },
        {
          "name": "Calculation of optimal PEEP",
          "type": "PROCEDURE"
        },
        {
          "name": "Postoperative CPAP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Fundación para la Investigación del Hospital Clínico de Valencia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 920,
      "start_date": "2014-09",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-05-17",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02158923"
    },
    {
      "nct_id": "NCT00053352",
      "title": "Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Childhood Embryonal Tumor",
        "Childhood Extracranial Germ Cell Tumor",
        "Childhood Extragonadal Germ Cell Tumor",
        "Childhood Malignant Ovarian Germ Cell Tumor",
        "Childhood Malignant Testicular Germ Cell Tumor",
        "Childhood Teratoma",
        "Ovarian Embryonal Carcinoma",
        "Ovarian Yolk Sac Tumor",
        "Stage II Malignant Testicular Germ Cell Tumor",
        "Stage IIA Ovarian Germ Cell Tumor",
        "Stage IIB Ovarian Germ Cell Tumor",
        "Stage IIC Ovarian Germ Cell Tumor",
        "Stage III Malignant Testicular Germ Cell Tumor",
        "Stage IIIA Ovarian Germ Cell Tumor",
        "Stage IIIB Ovarian Germ Cell Tumor",
        "Stage IIIC Ovarian Germ Cell Tumor",
        "Testicular Choriocarcinoma and Yolk Sac Tumor",
        "Testicular Embryonal Carcinoma"
      ],
      "interventions": [
        {
          "name": "conventional surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "cisplatin",
          "type": "DRUG"
        },
        {
          "name": "etoposide",
          "type": "DRUG"
        },
        {
          "name": "bleomycin sulfate",
          "type": "BIOLOGICAL"
        },
        {
          "name": "laboratory biomarker analysis",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Children's Oncology Group",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "Up to 21 Years"
      },
      "enrollment_count": 302,
      "start_date": "2003-11-03",
      "completion_date": "2021-06-30",
      "has_results": true,
      "last_update_posted_date": "2021-07-13",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 112,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 98 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00053352"
    },
    {
      "nct_id": "NCT04814992",
      "title": "Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Post-Surgical Pain"
      ],
      "interventions": [
        {
          "name": "Computer-Assisted Preoperative CBT Intervention (PAINTrainer)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2020-10-01",
      "completion_date": "2023-12-31",
      "has_results": true,
      "last_update_posted_date": "2024-10-17",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 4,
      "location_summary": "Philadelphia, Pennsylvania • Radnor, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Radnor",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04814992"
    },
    {
      "nct_id": "NCT07140679",
      "title": "Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Localized Colon Carcinoma",
        "Stage IIB Colon Cancer AJCC v8",
        "Stage IIC Colon Cancer AJCC v8",
        "Stage III Colon Cancer AJCC v8"
      ],
      "interventions": [
        {
          "name": "Biopsy Procedure",
          "type": "PROCEDURE"
        },
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Colonoscopy",
          "type": "PROCEDURE"
        },
        {
          "name": "Computed Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Toripalimab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2025-09-19",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-25",
      "last_synced_at": "2026-07-23T18:13:01.389Z",
      "location_count": 5,
      "location_summary": "Atlanta, Georgia • Johns Creek, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Johns Creek",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07140679"
    }
  ]
}