{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Rupture+of+Anterior+Cruciate+Ligament&page=2",
    "query": {
      "condition": "Rupture of Anterior Cruciate Ligament",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Rupture+of+Anterior+Cruciate+Ligament&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T12:25:54.175Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07115056",
      "title": "Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "ACL Injury",
        "ACL Tears",
        "ACL Surgery"
      ],
      "interventions": [
        {
          "name": "Tranexamic Acid (TXA)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Campbell Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "22 Years",
        "sex": "ALL",
        "summary": "14 Years to 22 Years"
      },
      "enrollment_count": 0,
      "start_date": "2026-04-01",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-03",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 6,
      "location_summary": "Evanston, Illinois • Chesterfield, Missouri • Durham, North Carolina + 3 more",
      "locations": [
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Chesterfield",
          "state": "Missouri"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07115056"
    },
    {
      "nct_id": "NCT03389685",
      "title": "Can PRP Reduce Pro-Inflammatory Biomarkers Following ACL Injury",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "ACL - Anterior Cruciate Ligament Rupture",
        "ACL Injury"
      ],
      "interventions": [
        {
          "name": "Platelet Rich Plasma",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Saline Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-09-09",
      "completion_date": "2024-02",
      "has_results": false,
      "last_update_posted_date": "2024-04-15",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03389685"
    },
    {
      "nct_id": "NCT04331002",
      "title": "Success of Long-acting Anti-inflammatories After Anterior Cruciate Ligament and Meniscal Injury",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tibial Meniscus Injuries",
        "Tibial Meniscus Tears",
        "Tibial Meniscus, Torn",
        "Anterior Cruciate Ligament Tear"
      ],
      "interventions": [
        {
          "name": "Zilretta",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Austin V Stone",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 1,
      "start_date": "2020-08-21",
      "completion_date": "2022-07-11",
      "has_results": true,
      "last_update_posted_date": "2023-07-27",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04331002"
    },
    {
      "nct_id": "NCT05190120",
      "title": "Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear",
        "Knee Meniscus Tear"
      ],
      "interventions": [
        {
          "name": "Femoral Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Adductor Canal Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine",
          "type": "DRUG"
        },
        {
          "name": "Preoperative Adductor canal block with 0.75%% ropivacaine 13.3ml.",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2016-01",
      "completion_date": "2022-03-20",
      "has_results": true,
      "last_update_posted_date": "2025-09-30",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05190120"
    },
    {
      "nct_id": "NCT04593264",
      "title": "Quantifying the Benefits of Supervised vs. Unsupervised Pre-habilitation for Patients With Acute ACL Tears",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Rupture",
        "Anterior Cruciate Ligament Tear",
        "Anterior Cruciate Ligament Injuries"
      ],
      "interventions": [
        {
          "name": "Self-guided pre-habilitation exercise program",
          "type": "OTHER"
        },
        {
          "name": "Traditional pre-habilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "WellSpan Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "13 Years to 50 Years"
      },
      "enrollment_count": 128,
      "start_date": "2021-02-23",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2023-03-27",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 1,
      "location_summary": "York, Pennsylvania",
      "locations": [
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04593264"
    },
    {
      "nct_id": "NCT04088227",
      "title": "Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Tear",
        "Anterior Cruciate Ligament Rupture"
      ],
      "interventions": [
        {
          "name": "Experimental Group",
          "type": "DRUG"
        },
        {
          "name": "Control Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Andrews Research & Education Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "14 Years to 40 Years"
      },
      "enrollment_count": 24,
      "start_date": "2019-09-12",
      "completion_date": "2023-04-21",
      "has_results": true,
      "last_update_posted_date": "2025-02-17",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 1,
      "location_summary": "Gulf Breeze, Florida",
      "locations": [
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04088227"
    },
    {
      "nct_id": "NCT05735236",
      "title": "Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL Tear"
      ],
      "interventions": [
        {
          "name": "BFR Cuff",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "16 Years to 60 Years"
      },
      "enrollment_count": 78,
      "start_date": "2022-11-08",
      "completion_date": "2025-11-08",
      "has_results": false,
      "last_update_posted_date": "2025-05-08",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 1,
      "location_summary": "Centennial, Colorado",
      "locations": [
        {
          "city": "Centennial",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05735236"
    },
    {
      "nct_id": "NCT03294759",
      "title": "Bio ACL Reconstruction Amnion Collagen Matrix Wrap and Stem Cells",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL - Anterior Cruciate Ligament Rupture"
      ],
      "interventions": [
        {
          "name": "Bio ACL",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Andrews Research & Education Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 40,
      "start_date": "2017-09-06",
      "completion_date": "2024-12-06",
      "has_results": false,
      "last_update_posted_date": "2024-02-21",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 1,
      "location_summary": "Gulf Breeze, Florida",
      "locations": [
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03294759"
    },
    {
      "nct_id": "NCT03617991",
      "title": "Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injury",
        "Anterior Cruciate Ligament Rupture"
      ],
      "interventions": [
        {
          "name": "Exercise Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johanna M. Hoch",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 27,
      "start_date": "2018-11-19",
      "completion_date": "2020-04-30",
      "has_results": false,
      "last_update_posted_date": "2020-05-04",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03617991"
    },
    {
      "nct_id": "NCT03429140",
      "title": "Early Anti-inflammatory Treatment in Patients With Acute ACL Tear and Painful Effusions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Anterior Cruciate Ligament"
      ],
      "interventions": [
        {
          "name": "Gel-One",
          "type": "DRUG"
        },
        {
          "name": "Saline Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Cale Jacobs, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "33 Years",
        "sex": "ALL",
        "summary": "14 Years to 33 Years"
      },
      "enrollment_count": 24,
      "start_date": "2017-04-06",
      "completion_date": "2019-06-23",
      "has_results": false,
      "last_update_posted_date": "2022-09-13",
      "last_synced_at": "2026-06-10T12:25:54.175Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03429140"
    }
  ]
}