{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Rupture+of+Membranes%3B+Premature%2C+Affecting+Fetus",
    "query": {
      "condition": "Rupture of Membranes; Premature, Affecting Fetus"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:06:20.268Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04478942",
      "title": "PROMMO Trial: Oral Misoprostol vs IV Oxytocin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Premature Rupture of Membrane",
        "Induction of Labor Affected Fetus / Newborn"
      ],
      "interventions": [
        {
          "name": "Misoprostol Oral Product",
          "type": "DRUG"
        },
        {
          "name": "Intravenous Oxytocin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 138,
      "start_date": "2020-10-26",
      "completion_date": "2025-01-14",
      "has_results": false,
      "last_update_posted_date": "2025-08-28",
      "last_synced_at": "2026-05-22T09:06:20.268Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04478942"
    },
    {
      "nct_id": "NCT04047849",
      "title": "Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture)",
        "Rupture of Membranes; Premature",
        "Rupture of Membranes; Premature, Affecting Fetus",
        "Preterm Birth",
        "Preterm PROM (Pregnancy)",
        "Preterm Labor"
      ],
      "interventions": [
        {
          "name": "Antibiotics, oral Azithromycin and oral Amoxicillin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Woman's",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 34,
      "start_date": "2019-08-28",
      "completion_date": "2021-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-01-11",
      "last_synced_at": "2026-05-22T09:06:20.268Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04047849"
    },
    {
      "nct_id": "NCT04513691",
      "title": "A Chart Review of Newborns With the Presence of Confirmed or Suspected Maternal Chorioamnionitis and Utilization of the Early Onset Sepsis Calculator",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Maternal; Chorioamnionitis, Affecting Fetus",
        "Early-Onset Sepses, Neonatal"
      ],
      "interventions": [
        {
          "name": "EOS Calculator",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Pediatrix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Weeks and older"
      },
      "enrollment_count": 236,
      "start_date": "2020-09-30",
      "completion_date": "2022-08-10",
      "has_results": false,
      "last_update_posted_date": "2022-11-22",
      "last_synced_at": "2026-05-22T09:06:20.268Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04513691"
    }
  ]
}