{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=SIRS&page=2",
    "query": {
      "condition": "SIRS",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=SIRS&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T19:38:17.802Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02568410",
      "title": "Platelets as Regulators of Inflammation in Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Systemic Inflammatory Response Syndrome",
        "Acute Kidney Injury"
      ],
      "interventions": [
        {
          "name": "coronary artery bypass grafting using cardiopulmonary bypass",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 99,
      "start_date": "2015-10",
      "completion_date": "2019-05",
      "has_results": false,
      "last_update_posted_date": "2019-05-23",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02568410"
    },
    {
      "nct_id": "NCT06669403",
      "title": "OPT101 in Patients With Community Acquired Pneumonia (CAP) With Sepsis",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Sepsis",
        "Community Acquired Pneumonia (CAP)"
      ],
      "interventions": [
        {
          "name": "OPT101",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Op-T LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2025-12",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2025-09-15",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06669403"
    },
    {
      "nct_id": "NCT02410486",
      "title": "Early-Onset Sepsis an NICHD/CDC Surveillance Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infant, Newborn, Diseases",
        "Early Onset Neonatal Sepsis",
        "Early-Onset Meningitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "Up to 72 Hours"
      },
      "enrollment_count": 570,
      "start_date": "2015-04",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2019-03-11",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 20,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 16 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02410486"
    },
    {
      "nct_id": "NCT07634419",
      "title": "Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Heart Failure",
        "Sepsis",
        "Ards",
        "Pneumonia",
        "Trauma Injury"
      ],
      "interventions": [
        {
          "name": "Lift mobile mindfulness",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enlighten Recovery education program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 450,
      "start_date": "2027-01-01",
      "completion_date": "2031-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-08",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 3,
      "location_summary": "Los Angeles, California • Durham, North Carolina • Charleston, South Carolina",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07634419"
    },
    {
      "nct_id": "NCT02052895",
      "title": "Utility of Presepsin in Distinguishing Between Sepsis and SIRS",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "SIRS",
        "Sepsis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mochida Pharmaceutical Company, Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 226,
      "start_date": "2014-01",
      "completion_date": "2015-07",
      "has_results": true,
      "last_update_posted_date": "2018-08-21",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02052895"
    },
    {
      "nct_id": "NCT06772675",
      "title": "Vancomycin Reduction Practices (VRP) in the NICU",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Antibiotic Stewardship",
        "Neonatal Sepsis, Late-Onset",
        "Vancomycin"
      ],
      "interventions": [
        {
          "name": "External Facilitation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2025-06-02",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 13,
      "location_summary": "Modesto, California • Oakland, California • Roseville, California + 9 more",
      "locations": [
        {
          "city": "Modesto",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Roseville",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Leandro",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06772675"
    },
    {
      "nct_id": "NCT01573806",
      "title": "Pharmacology of Exenatide in Pediatric Sepsis",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Septic Shock",
        "Inflammation",
        "Glucose Homeostasis",
        "Organ Dysfunction",
        "Health-related Quality of Life"
      ],
      "interventions": [
        {
          "name": "Exenatide",
          "type": "DRUG"
        },
        {
          "name": "Exenatide vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Month to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": "2012-10",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2017-10-05",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01573806"
    },
    {
      "nct_id": "NCT03162250",
      "title": "Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Participants With Staphylococcus Aureus Bacteremia Receiving Standard-of-Care (SOC) Antibiotics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Bacteremia"
      ],
      "interventions": [
        {
          "name": "DSTA4637S",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "SOC",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Genentech, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 27,
      "start_date": "2017-07-13",
      "completion_date": "2020-01-15",
      "has_results": false,
      "last_update_posted_date": "2020-01-22",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 4,
      "location_summary": "Torrance, California • Detroit, Michigan • Royal Oak, Michigan + 1 more",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03162250"
    },
    {
      "nct_id": "NCT04340232",
      "title": "Safety and Efficacy of Baricitinib for COVID-19",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "Baricitinib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-03",
      "completion_date": "2021-10",
      "has_results": false,
      "last_update_posted_date": "2021-03-08",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04340232"
    },
    {
      "nct_id": "NCT01576003",
      "title": "Enteral Glutamine in Reducing Bloodstream Infections in Short Bowel Syndrome Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bloodstream Infections",
        "Short Bowel Syndrome",
        "Development",
        "Nutrition",
        "Biological Markers"
      ],
      "interventions": [
        {
          "name": "Glutamine",
          "type": "DRUG"
        },
        {
          "name": "L-alanine",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Weeks",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "6 Weeks to 12 Months"
      },
      "enrollment_count": 10,
      "start_date": "2012-04",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2020-06-11",
      "last_synced_at": "2026-07-23T19:38:17.802Z",
      "location_count": 2,
      "location_summary": "Ann Arbor, Michigan • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01576003"
    }
  ]
}