{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Safety+Issues&page=2",
    "query": {
      "condition": "Safety Issues",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Safety+Issues&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:04:59.617Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05413226",
      "title": "Effect of Different Ingestion Doses of Celastrol on Human Sperm Motility",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Safety Issues"
      ],
      "interventions": [
        {
          "name": "Celastrol",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Legend Labz, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "MALE",
        "summary": "18 Years to 40 Years · Male only"
      },
      "enrollment_count": 5,
      "start_date": "2021-09-28",
      "completion_date": "2022-07-15",
      "has_results": false,
      "last_update_posted_date": "2022-06-09",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05413226"
    },
    {
      "nct_id": "NCT03991637",
      "title": "Non-Invasive Blood Test Cross-Validation Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Reproducibility of Results",
        "Safety Issues"
      ],
      "interventions": [
        {
          "name": "Non-Invasive Comprehensive Metabolic Panel",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Joseph Allen Jr.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2018-07-18",
      "completion_date": "2019-03-01",
      "has_results": false,
      "last_update_posted_date": "2019-06-24",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 1,
      "location_summary": "Grand Forks, North Dakota",
      "locations": [
        {
          "city": "Grand Forks",
          "state": "North Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03991637"
    },
    {
      "nct_id": "NCT03038126",
      "title": "Care Coordination/Home Telehealth to Safeguard Care in CKD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Safety Issues",
        "Chronic Kidney Disease"
      ],
      "interventions": [
        {
          "name": "CCHT",
          "type": "OTHER"
        },
        {
          "name": "Usual care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 137,
      "start_date": "2014-05",
      "completion_date": "2018-08",
      "has_results": true,
      "last_update_posted_date": "2020-03-18",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03038126"
    },
    {
      "nct_id": "NCT04113343",
      "title": "Oral Remimazolam With and Without Alcohol in Healthy Female Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Safety Issues"
      ],
      "interventions": [
        {
          "name": "Remimazolam",
          "type": "DRUG"
        },
        {
          "name": "Alcohol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Paion UK Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 45 Years · Female only"
      },
      "enrollment_count": 21,
      "start_date": "2017-05-30",
      "completion_date": "2017-08-09",
      "has_results": false,
      "last_update_posted_date": "2019-10-02",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04113343"
    },
    {
      "nct_id": "NCT05978908",
      "title": "Phase1 First in Human Ascending Dose Study to Evaluate the Safety and Tolerability of FC-12738 in Health Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Safety Issues",
        "Tolerance"
      ],
      "interventions": [
        {
          "name": "FC-12738",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Neurodegenerative Disease Research Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 24,
      "start_date": "2024-02-20",
      "completion_date": "2024-06-28",
      "has_results": false,
      "last_update_posted_date": "2025-05-25",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 1,
      "location_summary": "Berlin, New Jersey",
      "locations": [
        {
          "city": "Berlin",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05978908"
    },
    {
      "nct_id": "NCT04335045",
      "title": "Phase I Study of PH100 (Ecklonia Cava Phlorotannins)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Safety Issues"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "PH100 100mg",
          "type": "DRUG"
        },
        {
          "name": "PH100 200mg",
          "type": "DRUG"
        },
        {
          "name": "PH100 400mg",
          "type": "DRUG"
        },
        {
          "name": "PH100 800mg",
          "type": "DRUG"
        },
        {
          "name": "PH100 1200mg",
          "type": "DRUG"
        },
        {
          "name": "PH100 1600mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Phloronol Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 48,
      "start_date": "2013-09-25",
      "completion_date": "2014-12-08",
      "has_results": false,
      "last_update_posted_date": "2020-04-06",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04335045"
    },
    {
      "nct_id": "NCT04301895",
      "title": "Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Opioid; Intoxication, Perception Disturbance (Acute)",
        "Acute Pain",
        "Overdose of Opiate",
        "Respiratory Depression",
        "Safety Issues"
      ],
      "interventions": [
        {
          "name": "Continuous conversational interaction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Remifentanil infusion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "20 Years to 55 Years"
      },
      "enrollment_count": 20,
      "start_date": "2019-04-30",
      "completion_date": "2019-09-03",
      "has_results": false,
      "last_update_posted_date": "2020-03-10",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04301895"
    },
    {
      "nct_id": "NCT06485141",
      "title": "BeSMART Secure Storage Counseling in the Inpatient Setting",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Firearm Injury",
        "Safety Issues"
      ],
      "interventions": [
        {
          "name": "Safe Storage Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Safe Kids Medication",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2025-09-20",
      "completion_date": "2026-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado • Nashville, Tennessee",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06485141"
    },
    {
      "nct_id": "NCT03006549",
      "title": "Using Emergency Manuals During Interprofessional Crisis Management: Are There Unintended Consequences?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Safety Issues"
      ],
      "interventions": [
        {
          "name": "Emergency Manual (Crisis Checklist)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2015-01-10",
      "completion_date": "2019-05-13",
      "has_results": false,
      "last_update_posted_date": "2019-08-05",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03006549"
    },
    {
      "nct_id": "NCT00845052",
      "title": "Survey of Housestaff Attitudes Toward Patient Care and Safety",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Safety Issues",
        "Patient Care"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 674,
      "start_date": "2008-07",
      "completion_date": "2011-09",
      "has_results": false,
      "last_update_posted_date": "2017-02-06",
      "last_synced_at": "2026-05-22T09:04:59.617Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00845052"
    }
  ]
}