{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Saliva+Altered",
    "query": {
      "condition": "Saliva Altered"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T00:30:10.742Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02108769",
      "title": "Yogic Breathing Changes Salivary Components",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Neurodegenerative Diseases",
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Yogic Breathing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2013-10",
      "completion_date": "2013-11",
      "has_results": false,
      "last_update_posted_date": "2014-04-09",
      "last_synced_at": "2026-07-23T00:30:10.742Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02108769"
    },
    {
      "nct_id": "NCT01458938",
      "title": "This Study is to Determine if Degenerative Spinal Pain and Disorders Cause the Levels of Substance P to Change in a Patients Saliva, Blood and/or Cerebrospinal Fluid.",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spinal Disease",
        "Spinal Radiculopathy",
        "Myelopathy",
        "Neurogenic Claudication"
      ],
      "interventions": [
        {
          "name": "treatment plan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Carolina Neurosurgery & Spine Associates",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 53,
      "start_date": "2009-07",
      "completion_date": "2014-04",
      "has_results": false,
      "last_update_posted_date": "2017-02-01",
      "last_synced_at": "2026-07-23T00:30:10.742Z",
      "location_count": 1,
      "location_summary": "Charlotte, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01458938"
    },
    {
      "nct_id": "NCT04107688",
      "title": "Taste Perception, Salivary Proteins & the Oral Microbiome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Saliva Altered",
        "Taste, Altered"
      ],
      "interventions": [
        {
          "name": "Control",
          "type": "OTHER"
        },
        {
          "name": "CPE",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rutgers University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 20,
      "start_date": "2019-03-25",
      "completion_date": "2019-04-19",
      "has_results": false,
      "last_update_posted_date": "2024-05-14",
      "last_synced_at": "2026-07-23T00:30:10.742Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04107688"
    },
    {
      "nct_id": "NCT03501238",
      "title": "Interaction of Salivary Proteins and Polyphenols",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diet Habit",
        "Diet Modification",
        "Taste, Altered",
        "Saliva Altered"
      ],
      "interventions": [
        {
          "name": "Chocolate Milk",
          "type": "OTHER"
        },
        {
          "name": "Chocolate milk substitute",
          "type": "OTHER"
        },
        {
          "name": "Chocolate milk substitute with gelatin",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 63,
      "start_date": "2017-06-08",
      "completion_date": "2018-01-01",
      "has_results": false,
      "last_update_posted_date": "2023-05-25",
      "last_synced_at": "2026-07-23T00:30:10.742Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03501238"
    },
    {
      "nct_id": "NCT05819073",
      "title": "Astringency and Oral Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Saliva Altered",
        "Taste, Altered"
      ],
      "interventions": [
        {
          "name": "Plain water",
          "type": "OTHER"
        },
        {
          "name": "CPE",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 49,
      "start_date": "2022-11-01",
      "completion_date": "2023-11-14",
      "has_results": false,
      "last_update_posted_date": "2025-03-28",
      "last_synced_at": "2026-07-23T00:30:10.742Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05819073"
    },
    {
      "nct_id": "NCT06107231",
      "title": "WHNRC (Western Human Nutrition Research Center) Honey Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postprandial Glycemia",
        "Metabolic Stress",
        "Cognitive Change",
        "Satisfaction, Personal"
      ],
      "interventions": [
        {
          "name": "Honey",
          "type": "OTHER"
        },
        {
          "name": "Sucrose",
          "type": "OTHER"
        },
        {
          "name": "Honey plus almonds",
          "type": "OTHER"
        },
        {
          "name": "Sucrose plus almonds",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "USDA, Western Human Nutrition Research Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 58,
      "start_date": "2024-01-16",
      "completion_date": "2026-10-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-29",
      "last_synced_at": "2026-07-23T00:30:10.742Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06107231"
    },
    {
      "nct_id": "NCT05447104",
      "title": "Salivary Flow Promoted by Sugar-Free Chewing Gum",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Saliva Altered"
      ],
      "interventions": [
        {
          "name": "Mastication",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mars Wrigley",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 16,
      "start_date": "2021-09-22",
      "completion_date": "2021-11-12",
      "has_results": false,
      "last_update_posted_date": "2022-07-07",
      "last_synced_at": "2026-07-23T00:30:10.742Z",
      "location_count": 1,
      "location_summary": "Noblesville, Indiana",
      "locations": [
        {
          "city": "Noblesville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05447104"
    },
    {
      "nct_id": "NCT00007488",
      "title": "HIV in Specific Parts of the Body of Patients Who Are Changing or Starting Potent Anti-HIV Drugs",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 164,
      "start_date": "2000-11",
      "completion_date": "2004-08",
      "has_results": false,
      "last_update_posted_date": "2013-11-20",
      "last_synced_at": "2026-07-23T00:30:10.742Z",
      "location_count": 23,
      "location_summary": "Los Angeles, California • Menlo Park, California • San Diego, California + 14 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Menlo Park",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00007488"
    }
  ]
}