{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Scleroderma%2C+Diffuse", "query": { "condition": "Scleroderma, Diffuse" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 254, "total_pages": 26, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Scleroderma%2C+Diffuse&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-10T10:07:28.045Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02370693", "title": "Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary Fibrosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Lung Diseases, Interstitial", "Systemic Sclerosis", "Scleroderma" ], "interventions": [ { "name": "Bortezomib", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Mycophenolate mofetil", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 9, "start_date": "2016-03", "completion_date": "2020-01-01", "has_results": true, "last_update_posted_date": "2021-08-25", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02370693" }, { "nct_id": "NCT00775463", "title": "Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Systemic Sclerosis", "Scleroderma" ], "interventions": [ { "name": "treprostinil diethanolamine", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "United Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 148, "start_date": "2009-05", "completion_date": "2011-07", "has_results": true, "last_update_posted_date": "2023-12-28", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 24, "location_summary": "Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 21 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT00775463" }, { "nct_id": "NCT04610788", "title": "Cardiac Assessment by PV Loop in IPAH and Scleroderma PAH", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Scleroderma", "Pulmonary Artery Hypertension" ], "interventions": [], "intervention_types": [], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 43, "start_date": "2019-04-15", "completion_date": "2025-12-31", "has_results": false, "last_update_posted_date": "2026-01-09", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04610788" }, { "nct_id": "NCT07038447", "title": "A Study of KITE-363 in Participants With Refractory Autoimmune Diseases", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Systemic Lupus Erythematosus", "Lupus Nephritis", "Systemic Sclerosis", "Idiopathic Inflammatory Myopathy" ], "interventions": [ { "name": "KITE-363", "type": "BIOLOGICAL" }, { "name": "Fludarabine", "type": "DRUG" }, { "name": "Cyclophosphamide", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Kite, A Gilead Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 52, "start_date": "2025-07-02", "completion_date": "2029-07", "has_results": false, "last_update_posted_date": "2026-04-06", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 2, "location_summary": "Duarte, California • Stanford, California", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07038447" }, { "nct_id": "NCT01538719", "title": "IL1-TRAP, Rilonacept, in Systemic Sclerosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Scleroderma", "Systemic Sclerosis", "Diffuse Scleroderma", "Diffuse Systemic Sclerosis" ], "interventions": [ { "name": "Rilonacept", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Boston University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 24, "start_date": "2011-12", "completion_date": "2017-08-11", "has_results": true, "last_update_posted_date": "2018-05-01", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01538719" }, { "nct_id": "NCT04440592", "title": "Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Diffuse Cutaneous Systemic Sclerosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diffuse Cutaneous Systemic Sclerosis" ], "interventions": [ { "name": "MT-7117", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Tanabe Pharma America, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 76, "start_date": "2021-02-05", "completion_date": "2024-02-14", "has_results": true, "last_update_posted_date": "2025-12-30", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 11, "location_summary": "Glendale, Arizona • Los Angeles, California • Redwood City, California + 8 more", "locations": [ { "city": "Glendale", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Redwood City", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Hollywood", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04440592" }, { "nct_id": "NCT04680975", "title": "Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic Sclerosis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diffuse Cutaneous Systemic Sclerosis" ], "interventions": [ { "name": "Belumosudil", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kadmon, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2021-03-03", "completion_date": "2022-12-19", "has_results": true, "last_update_posted_date": "2023-06-05", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 6, "location_summary": "Los Angeles, California • New Haven, Connecticut • Chicago, Illinois + 3 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Chicago", "state": "Illinois" }, { "city": "New York", "state": "New York" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT04680975" }, { "nct_id": "NCT02283762", "title": "Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Scleroderma, Systemic" ], "interventions": [ { "name": "Riociguat (Adempas, BAY63-2521)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 121, "start_date": "2015-01-15", "completion_date": "2019-03-28", "has_results": true, "last_update_posted_date": "2020-02-05", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 10, "location_summary": "Scottsdale, Arizona • Los Angeles, California • Palo Alto, California + 7 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Farmington", "state": "Connecticut" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02283762" }, { "nct_id": "NCT00577304", "title": "A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenon", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Raynaud's Disease", "Raynaud's Disease Secondary to Scleroderma", "Raynaud's Disease Secondary to Other Autoimmune Disease" ], "interventions": [ { "name": "Nitroglycerin", "type": "DRUG" }, { "name": "Topical AmphiMatrix", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "MediQuest Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "15 Years to 70 Years" }, "enrollment_count": 200, "start_date": "2007-12", "completion_date": "2008-03", "has_results": false, "last_update_posted_date": "2010-02-05", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 17, "location_summary": "Stanford, California • Denver, Colorado • Farmington, Connecticut + 14 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Farmington", "state": "Connecticut" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00577304" }, { "nct_id": "NCT04138485", "title": "Efficacy and Safety of IgPro10 in Adults With Systemic Sclerosis (SSc)", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diffuse Cutaneous Systemic Sclerosis" ], "interventions": [ { "name": "IgPro10", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "CSL Behring", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2019-12-20", "completion_date": "2020-09-16", "has_results": false, "last_update_posted_date": "2020-11-17", "last_synced_at": "2026-06-10T10:07:28.045Z", "location_count": 20, "location_summary": "Scottsdale, Arizona • Los Angeles, California • Palo Alto, California + 15 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04138485" } ] }