{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Scleroderma%2C+Localized",
    "query": {
      "condition": "Scleroderma, Localized"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Scleroderma%2C+Localized&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:34:03.196Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03679845",
      "title": "Study to Assess Sarilumab in Halting Progression of Morphea",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Morphea, Plaque Form"
      ],
      "interventions": [
        {
          "name": "Sarilumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2019-09-01",
      "completion_date": "2021-06-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-08",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03679845"
    },
    {
      "nct_id": "NCT01808937",
      "title": "Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Scleroderma, Localized",
        "Morphea",
        "Frontal Linear Scleroderma en Coup de Sabre",
        "Scleroderma, Circumscribed",
        "Scleroderma, Linear"
      ],
      "interventions": [
        {
          "name": "Morphea",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "Up to 90 Years"
      },
      "enrollment_count": 500,
      "start_date": "2007-05",
      "completion_date": "2028-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01808937"
    },
    {
      "nct_id": "NCT00476697",
      "title": "UVA1 Light for Scleroderma and Similar Conditions",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Keloid",
        "Scleroderma",
        "Scars",
        "Granuloma Annulare",
        "Acne Keloidalis Nuchae"
      ],
      "interventions": [
        {
          "name": "German manufactured UVA1 emitting light system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "10 Years to 80 Years"
      },
      "enrollment_count": 23,
      "start_date": "1997-01",
      "completion_date": "2003-07",
      "has_results": false,
      "last_update_posted_date": "2015-07-27",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00476697"
    },
    {
      "nct_id": "NCT03351114",
      "title": "Pilot Study Evaluating the Efficacy of a Topical PDE4 Inhibitor for Morphea",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Morphea"
      ],
      "interventions": [
        {
          "name": "Crisaborole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2018-09-01",
      "completion_date": "2020-03-10",
      "has_results": true,
      "last_update_posted_date": "2021-04-01",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03351114"
    },
    {
      "nct_id": "NCT01799174",
      "title": "Treatment Study Comparing UVA-1 Phototherapy Versus Placebo Treatment for Morphea",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Scleroderma, Localized",
        "Morphea",
        "Scleroderma, Circumscribed"
      ],
      "interventions": [
        {
          "name": "UVA-1 Phototherapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "6 Years to 95 Years"
      },
      "enrollment_count": 14,
      "start_date": "2012-05",
      "completion_date": "2019-09-13",
      "has_results": false,
      "last_update_posted_date": "2019-09-25",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01799174"
    },
    {
      "nct_id": "NCT00476801",
      "title": "UVA1 Light for Treatment of Scleroderma and Similar Conditions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Scleroderma",
        "Keloids",
        "Other Fibrosing Conditions"
      ],
      "interventions": [
        {
          "name": "German manufactured UVA1 light emitting device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "10 Years to 80 Years"
      },
      "enrollment_count": 27,
      "start_date": "2001-07",
      "completion_date": "2004-02",
      "has_results": false,
      "last_update_posted_date": "2015-07-10",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00476801"
    },
    {
      "nct_id": "NCT01758250",
      "title": "Microvascular and Fibrosis Imaging Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autoimmune Diseases",
        "Sickle Cell Disease",
        "Chronic Graft Versus Host Disease"
      ],
      "interventions": [
        {
          "name": "Acoustic Radiation Force Impulse (ARFI)",
          "type": "OTHER"
        },
        {
          "name": "Laser Doppler Flowmetry (LDF)",
          "type": "OTHER"
        },
        {
          "name": "Laser Doppler Perfusion Imaging (LDI)",
          "type": "OTHER"
        },
        {
          "name": "Optical Coherence Tomography (OCT)",
          "type": "OTHER"
        },
        {
          "name": "Orthogonal Polarization Spectral Imaging (OPSI)",
          "type": "OTHER"
        },
        {
          "name": "Nail fold video capillaroscopy (NVC)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 63,
      "start_date": "2013-02",
      "completion_date": "2018-02",
      "has_results": false,
      "last_update_posted_date": "2020-09-11",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01758250"
    },
    {
      "nct_id": "NCT02411643",
      "title": "Molecular Effects of Topical Calcipotriene on Morphea",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Morphea",
        "Localized Scleroderma"
      ],
      "interventions": [
        {
          "name": "topical calcipotriene 0.005% ointment",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2015-03",
      "completion_date": "2016-04",
      "has_results": true,
      "last_update_posted_date": "2018-09-13",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02411643"
    },
    {
      "nct_id": "NCT00001330",
      "title": "Study of Silicone-Associated Connective Tissue Diseases",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autoimmune Diseases",
        "Connective Tissue Diseases",
        "Scleroderma, Circumscribed",
        "Scleroderma, Systemic"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 60,
      "start_date": "1992-11",
      "completion_date": "2000-10",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001330"
    },
    {
      "nct_id": "NCT03740724",
      "title": "A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Morphea",
        "Scleroderma, Localized",
        "Scleroderma"
      ],
      "interventions": [
        {
          "name": "FCX-013",
          "type": "GENETIC"
        },
        {
          "name": "veledimex",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "GENETIC",
        "DRUG"
      ],
      "sponsor": "Castle Creek Biosciences, LLC.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2019-12-18",
      "completion_date": "2022-04-21",
      "has_results": true,
      "last_update_posted_date": "2024-01-23",
      "last_synced_at": "2026-05-22T05:34:03.196Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03740724"
    }
  ]
}