{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Secondary+Lymphedema",
    "query": {
      "condition": "Secondary Lymphedema"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 20,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Secondary+Lymphedema&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:45:54.922Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03634462",
      "title": "Complete Decongestive Therapy With Negative Pressure for Lipedema and Lymphedema Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lipedema",
        "Secondary Lymphedema"
      ],
      "interventions": [
        {
          "name": "CDT with graded negative pressure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "90 Years",
        "sex": "FEMALE",
        "summary": "14 Years to 90 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2019-01-15",
      "completion_date": "2020-02-28",
      "has_results": false,
      "last_update_posted_date": "2020-05-19",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03634462"
    },
    {
      "nct_id": "NCT01928030",
      "title": "Recombinant Human Hyaluronidase in Treating Lymphedema in Patients With Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Lymphedema",
        "Malignant Neoplasm"
      ],
      "interventions": [
        {
          "name": "recombinant human hyaluronidase",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 3,
      "start_date": "2013-12",
      "completion_date": "2015-11",
      "has_results": true,
      "last_update_posted_date": "2017-03-21",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01928030"
    },
    {
      "nct_id": "NCT05485454",
      "title": "A Preference Study of Two Pneumatic Compression Devices for Patients With Lower Limb Lymphedema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lymphedema of Leg",
        "Lymphedema",
        "Lymphedema, Secondary",
        "Lymphedema Primary",
        "Lymphedema, Lower Limb"
      ],
      "interventions": [
        {
          "name": "Aria Health Aria Free",
          "type": "DEVICE"
        },
        {
          "name": "A Traditional PCD",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ResMed",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2022-06-11",
      "completion_date": "2022-07-30",
      "has_results": false,
      "last_update_posted_date": "2022-09-15",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05485454"
    },
    {
      "nct_id": "NCT02528539",
      "title": "Prevention of Lymphedema Among Breast Cancer Patients Through Implementation of an Integrative Therapy Program (ITP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lymphedema"
      ],
      "interventions": [
        {
          "name": "ITP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Huntington Memorial Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2013-08",
      "completion_date": "2016-12-30",
      "has_results": false,
      "last_update_posted_date": "2022-03-02",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 1,
      "location_summary": "Pasadena, California",
      "locations": [
        {
          "city": "Pasadena",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02528539"
    },
    {
      "nct_id": "NCT04897035",
      "title": "Study to Evaluate the Safety and Effectiveness of Dayspring for Lower Extremity Lymphedema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lymphedema",
        "Lymphedema Lower Extremity",
        "Chronic Venous Insufficiency",
        "Secondary Lymphedema"
      ],
      "interventions": [
        {
          "name": "Dayspring Active Wearable Compression System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Koya Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2021-06-01",
      "completion_date": "2022-07-01",
      "has_results": true,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 2,
      "location_summary": "Los Altos, California • Morgan Hill, California",
      "locations": [
        {
          "city": "Los Altos",
          "state": "California"
        },
        {
          "city": "Morgan Hill",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04897035"
    },
    {
      "nct_id": "NCT04243837",
      "title": "LYT-100 in Patients With BCRL",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer Related Lymphoedema",
        "Lymphoedema"
      ],
      "interventions": [
        {
          "name": "LYT-100 BCRL",
          "type": "DRUG"
        },
        {
          "name": "Placebo BCRL",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "PureTech",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2020-03-01",
      "completion_date": "2022-09-09",
      "has_results": true,
      "last_update_posted_date": "2024-04-23",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 4,
      "location_summary": "Duarte, California • Los Angeles, California • Maitland, Florida + 1 more",
      "locations": [
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04243837"
    },
    {
      "nct_id": "NCT04797390",
      "title": "A Study Evaluating an Advanced Pneumatic Compression Device Versus Usual Care for Treatment of Head and Neck Lymphedema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lymphedema",
        "Lymphedema of Face",
        "Lymphedema, Secondary",
        "Lymphedema Due to Radiation",
        "Lymphedema; Surgical"
      ],
      "interventions": [
        {
          "name": "Advanced Pneumatic Compression Device (APCD)",
          "type": "DEVICE"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Tactile Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 236,
      "start_date": "2021-09-23",
      "completion_date": "2024-12-03",
      "has_results": true,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • Chicago, Illinois • Louisville, Kentucky + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04797390"
    },
    {
      "nct_id": "NCT03252145",
      "title": "Treatment of Breast Cancer-related Lymphedema With a Negative Pressure Device",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lymphedema, Secondary",
        "Lymphedema of Upper Limb"
      ],
      "interventions": [
        {
          "name": "PhysioTouch",
          "type": "DEVICE"
        },
        {
          "name": "Manual Lymph Drainage (MLD)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 28,
      "start_date": "2017-10-31",
      "completion_date": "2020-01-31",
      "has_results": true,
      "last_update_posted_date": "2021-01-15",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03252145"
    },
    {
      "nct_id": "NCT04457375",
      "title": "Skin Biophysical Measures for Assessing Head and Neck Cancer-Related External Lymphedema",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphedema, Secondary"
      ],
      "interventions": [
        {
          "name": "TDC",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Nova Southeastern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2020-01-16",
      "completion_date": "2021-01-15",
      "has_results": false,
      "last_update_posted_date": "2021-06-09",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 1,
      "location_summary": "Fort Lauderdale, Florida",
      "locations": [
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04457375"
    },
    {
      "nct_id": "NCT02156115",
      "title": "Characterization of the Pathogenesis of Primary and Secondary Lymphatic Disorders",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphangiomatosis",
        "Lymphedema",
        "Lymphangiectasia",
        "Pulmonary Lymphangiectasia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "2 Years to 90 Years"
      },
      "enrollment_count": 14,
      "start_date": "2015-03-23",
      "completion_date": "2024-04-01",
      "has_results": false,
      "last_update_posted_date": "2024-04-11",
      "last_synced_at": "2026-05-22T08:45:54.922Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02156115"
    }
  ]
}