{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Semantic+Aphasia",
    "query": {
      "condition": "Semantic Aphasia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 18,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Semantic+Aphasia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:37:20.784Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02005016",
      "title": "Dosage and Predictors of Naming Treatment Response in Aphasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aphasia",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Naming therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 46,
      "start_date": "2013-10-01",
      "completion_date": "2018-09-30",
      "has_results": true,
      "last_update_posted_date": "2019-11-04",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02005016"
    },
    {
      "nct_id": "NCT05901233",
      "title": "Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Progressive Aphasia"
      ],
      "interventions": [
        {
          "name": "Remotely supervised Transcranial Direct Current Stimulation (RS-tDCS)",
          "type": "DEVICE"
        },
        {
          "name": "Remotely supervised sham tDCS (RS-sham-tDCS)",
          "type": "DEVICE"
        },
        {
          "name": "Lexical Retrieval Training (LRT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Video Implemented Script Training in Aphasia (VISTA)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 10,
      "start_date": "2023-07-10",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-10-08",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Austin, Texas",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05901233"
    },
    {
      "nct_id": "NCT04680130",
      "title": "Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PSP",
        "CBD",
        "PCA",
        "LPA",
        "Semantic Dementia",
        "Semantic Aphasia",
        "Behavioral Variant of Frontotemporal Dementia",
        "FTD",
        "PPA",
        "Apraxia of Speech",
        "MSA - Multiple System Atrophy",
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "C-11 PiB",
          "type": "DRUG"
        },
        {
          "name": "AV1451 Tau",
          "type": "DRUG"
        },
        {
          "name": "C-11 ER176",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2020-11-01",
      "completion_date": "2050-11",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04680130"
    },
    {
      "nct_id": "NCT02365922",
      "title": "Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "FTLD",
        "Progressive Supranuclear Palsy (PSP)",
        "Frontotemporal Dementia (FTD)",
        "Corticobasal Degeneration (CBD)",
        "PPA Syndrome",
        "Behavioral Variant Frontotemporal Dementia (bvFTD)",
        "Semantic Variant Primary Progressive Aphasia (svPPA)",
        "Nonfluent Variant Primary Progressive Aphasia (nfvPPA)",
        "FTD With Amyotrophic Lateral Sclerosis (FTD/ALS)",
        "Amyotrophic Lateral Sclerosis (ALS)",
        "Oligosymptomatic PSP (oPSP)",
        "Corticobasal Syndrome (CBS)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 1489,
      "start_date": "2014-09",
      "completion_date": "2020-09",
      "has_results": false,
      "last_update_posted_date": "2021-05-21",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 15,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • San Diego, California + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02365922"
    },
    {
      "nct_id": "NCT05184569",
      "title": "Veri-T: A Trial of Verdiperstat in Patients With svPPA Due to TDP-43 Pathology",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Semantic Dementia"
      ],
      "interventions": [
        {
          "name": "Verdiperstat",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Peter Ljubenkov, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 64,
      "start_date": "2022-04-14",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 5,
      "location_summary": "San Francisco, California • Chicago, Illinois • Rochester, Minnesota + 2 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05184569"
    },
    {
      "nct_id": "NCT01623284",
      "title": "PiB PET Scanning in Speech and Language Based Dementias",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "PPA",
        "Primary Progressive Aphasia",
        "Aphasia",
        "Non-fluent Aphasia",
        "Semantic Dementia",
        "Apraxia of Speech",
        "Primary Progressive Nonfluent Aphasia",
        "Progressive Aphasia"
      ],
      "interventions": [
        {
          "name": "C-11 PiB",
          "type": "DRUG"
        },
        {
          "name": "F-18 FDG",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 168,
      "start_date": "2010-03",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2015-12-22",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01623284"
    },
    {
      "nct_id": "NCT04881617",
      "title": "Treatment for Speech and Language in Primary Progressive Aphasia",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Progressive Aphasia",
        "Semantic Dementia",
        "Semantic Memory Disorder",
        "Logopenic Progressive Aphasia",
        "Nonfluent Aphasia, Progressive",
        "Aphasia",
        "Aphasia, Progressive"
      ],
      "interventions": [
        {
          "name": "Lexical Retrieval Training (LRT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Video-Implemented Script Training for Aphasia (VISTA)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 60,
      "start_date": "2017-07-01",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-13",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Austin, Texas",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04881617"
    },
    {
      "nct_id": "NCT00537004",
      "title": "Language in Primary Progressive Aphasia",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Primary Progressive Aphasia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 500,
      "start_date": "2007-05",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00537004"
    },
    {
      "nct_id": "NCT04188067",
      "title": "TMS for the Treatment of Primary Progressive Aphasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Logopenic Variant Primary Progressive Aphasia",
        "Non-fluent Variant Primary Progressive Aphasia",
        "Semantic Variant Primary Progressive Aphasia"
      ],
      "interventions": [
        {
          "name": "Active rTMS",
          "type": "DEVICE"
        },
        {
          "name": "SHAM rTMS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 10,
      "start_date": "2022-03-01",
      "completion_date": "2024-08-25",
      "has_results": true,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04188067"
    },
    {
      "nct_id": "NCT07036406",
      "title": "Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Aphasia",
        "Aphasia Following Cerebral Infarction",
        "Aphasia, Acquired",
        "Aphasia, Rehabilitation",
        "Aphasia, Anomic",
        "Aphasia, Broca",
        "Aphasia, Conduction",
        "Aphasia, Expressive",
        "Aphasia Non Fluent",
        "Aphasia, Mixed"
      ],
      "interventions": [
        {
          "name": "Semantic Feature Analysis (traditional)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Semantic Feature Analysis + Metacognitive Strategy Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Teachers College, Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-07-28",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2025-08-12",
      "last_synced_at": "2026-05-22T05:37:20.784Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07036406"
    }
  ]
}