{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Septal+Defect%2C+Atrial&page=2",
    "query": {
      "condition": "Septal Defect, Atrial",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Septal+Defect%2C+Atrial&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T01:44:28.911Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07629635",
      "title": "Migraine Headaches Elimination With Patent Foramen Ovale-Directed Therapy",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Migraine Disease",
        "Patent Foramen Ovale"
      ],
      "interventions": [
        {
          "name": "Prasugrel 5mg",
          "type": "DRUG"
        },
        {
          "name": "Transcatheter Closure of Patent Foramen Ovale",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 32,
      "start_date": "2026-09-01",
      "completion_date": "2028-03",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07629635"
    },
    {
      "nct_id": "NCT03373929",
      "title": "Stitch Closure of PFO and Septal Repair",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Foramen Ovale, Patent",
        "Septal Defect, Atrial",
        "Septal Defect, Heart"
      ],
      "interventions": [
        {
          "name": "PFO Closure Rate",
          "type": "DEVICE"
        },
        {
          "name": "Published PFO Device Closure",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "HeartStitch.Com",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 250,
      "start_date": "2017-11-20",
      "completion_date": "2022-11-20",
      "has_results": false,
      "last_update_posted_date": "2017-12-14",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 1,
      "location_summary": "Falls Church, Virginia",
      "locations": [
        {
          "city": "Falls Church",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03373929"
    },
    {
      "nct_id": "NCT03945643",
      "title": "Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Patent Foramen Ovale",
        "Intrapulmonary Arteriovenous Anastamosis"
      ],
      "interventions": [
        {
          "name": "Sildenafil",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Oregon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 82,
      "start_date": "2019-07-01",
      "completion_date": "2023-07-31",
      "has_results": false,
      "last_update_posted_date": "2023-08-14",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 1,
      "location_summary": "Eugene, Oregon",
      "locations": [
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03945643"
    },
    {
      "nct_id": "NCT00498446",
      "title": "Magnetic Resonance Imaging of Atrial Septal Defects",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrial Septal Defect"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2002-07",
      "completion_date": "2004-07",
      "has_results": false,
      "last_update_posted_date": "2023-10-26",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00498446"
    },
    {
      "nct_id": "NCT07519876",
      "title": "Pulmonary Embolism and Right-to-Left Shunts",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pulmonary Embolism (PE)",
        "Right-to-Left Shunt",
        "Stroke",
        "Atrial Septal Defects",
        "Patent Foramen Ovale (PFO)",
        "Pulmonary Arteriovenous Malformation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 256,
      "start_date": "2026-01-30",
      "completion_date": "2028-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07519876"
    },
    {
      "nct_id": "NCT05069558",
      "title": "Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Patent Foramen Ovale",
        "PFO"
      ],
      "interventions": [
        {
          "name": "Investigational PFO Closure Device",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care PFO Closure Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Occlutech International AB",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 450,
      "start_date": "2022-05-09",
      "completion_date": "2029-11",
      "has_results": false,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 27,
      "location_summary": "Phoenix, Arizona • Stanford, California • Thousand Oaks, California + 20 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Thousand Oaks",
          "state": "California"
        },
        {
          "city": "Lakewood",
          "state": "Colorado"
        },
        {
          "city": "Littleton",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05069558"
    },
    {
      "nct_id": "NCT00355056",
      "title": "PREMIUM Migraine Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine Headaches",
        "Patent Foramen Ovale"
      ],
      "interventions": [
        {
          "name": "Sham Procedure",
          "type": "OTHER"
        },
        {
          "name": "AMPLATZER PFO Occluder",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 230,
      "start_date": "2006-01",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2020-07-30",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 30,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Colorado Springs, Colorado + 23 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Englewood",
          "state": "Colorado"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00355056"
    },
    {
      "nct_id": "NCT01773252",
      "title": "Right to Left Cardiac Shunt Detection",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Right to Left Shunt",
        "Patent Foramen Ovale",
        "Atrial Septal Defect"
      ],
      "interventions": [
        {
          "name": "Flow Detection System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cardiox Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 141,
      "start_date": "2012-11",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2015-11-13",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 8,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 5 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01773252"
    },
    {
      "nct_id": "NCT04591392",
      "title": "Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Septal Defect",
        "Heart Septal Defects, Atrial",
        "Heart Defects, Congenital",
        "Cardiovascular Abnormalities",
        "Cardiovascular Diseases",
        "Heart Diseases",
        "Congenital Abnormalities"
      ],
      "interventions": [
        {
          "name": "reSept ASD Occluder",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "atHeart Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "Up to 84 Years"
      },
      "enrollment_count": 250,
      "start_date": "2021-03-12",
      "completion_date": "2032-03",
      "has_results": false,
      "last_update_posted_date": "2025-05-07",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 24,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Thousand Oaks, California + 21 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Thousand Oaks",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04591392"
    },
    {
      "nct_id": "NCT04339699",
      "title": "NobleStitch EL STITCH Trial is a PFO Comparative Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Foramen Ovale, Patent",
        "Stroke, Ischemic"
      ],
      "interventions": [
        {
          "name": "NobleStitch™EL Suture Mediated Closure System",
          "type": "DEVICE"
        },
        {
          "name": "Amplatzer PFO Occluder",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Nobles Medical Technologies II Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 640,
      "start_date": "2021-01-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-06-11T01:44:28.911Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04339699"
    }
  ]
}