{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Septic+Arthritis",
    "query": {
      "condition": "Septic Arthritis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Septic+Arthritis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:39:07.820Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03704766",
      "title": "Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Joint Infection",
        "Infection of Hip Joint (Disorder)",
        "Infection of Shoulder Joint",
        "Septic Arthritis"
      ],
      "interventions": [
        {
          "name": "Synovial Alpha-defensin assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Neutrophil elastase assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial lactate assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial C-reactive Protein (CRP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Staphylococcus spp antigen panel",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Candida spp antigen panel",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Enterococcus faecalis assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial bacterial culture by BacT/Alert",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Cell count + differential (CBC)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Gram Stain",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Leukocyte Esterase Test Strips",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial PCR for Kingella kingae",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum Cell count + differential (CBC)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum erythrocyte sedimentation rate (ESR)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum C-reactive Protein (CRP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum D-dimer",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum Procalcitonin",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Cultures",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Optional blood testing per standard of care (ASO, anti-strep, ANA, anti-DS-DNA, HLA-B27, RF, Lyme and other inflammatory/ rheumatologic markers )",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 442,
      "start_date": "2016-06-28",
      "completion_date": "2026-05",
      "has_results": false,
      "last_update_posted_date": "2025-06-22",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • New York, New York • Collierville, Tennessee",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Collierville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03704766"
    },
    {
      "nct_id": "NCT00313365",
      "title": "Surgical Lavage vs Serial Needle Aspiration for Infected Joints",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Arthritis",
        "Septic"
      ],
      "interventions": [
        {
          "name": "Surgical Lavage (Arthrotomy)",
          "type": "PROCEDURE"
        },
        {
          "name": "Arthrocentesis (Serial needle aspiration)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2006-04",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2013-09-24",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00313365"
    },
    {
      "nct_id": "NCT00001679",
      "title": "Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthritis, Reactive",
        "Arthritis, Rheumatoid",
        "Synovitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 250,
      "start_date": "1998-08",
      "completion_date": "2000-06",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001679"
    },
    {
      "nct_id": "NCT02498301",
      "title": "Trial Evaluating Chemoprophylaxis Against Travelers' Diarrhea - Prevent TD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Travelers' Diarrhea",
        "Functional Bowel Disorders",
        "Reactive Arthritis"
      ],
      "interventions": [
        {
          "name": "Rifaximin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 449,
      "start_date": "2015-11-10",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-02-15",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 5,
      "location_summary": "San Diego, California • Honolulu, Hawaii • Marine Corps Base Camp Lejeune, North Carolina + 2 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Marine Corps Base Camp Lejeune",
          "state": "North Carolina"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02498301"
    },
    {
      "nct_id": "NCT04846010",
      "title": "Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Sequelae of; Infection",
        "Post Infection Glomerulonephritis",
        "Post-Infectious Peripheral Neuralgia",
        "Post-Infectious Disorder (Disorder)",
        "Post-Infectious Arthritis",
        "Post-Infectious Polyneuritis",
        "Post-Infectious Parkinsonism",
        "Post-Infectious Hypothyroidism",
        "Post Infectious Osteoarthritis",
        "Anxiety Disorders",
        "Depression",
        "Depression, Anxiety",
        "Depression, Bipolar",
        "Insomnia",
        "GERD",
        "Gastro Esophageal Reflux",
        "Hepatitis",
        "Glomerulonephritis"
      ],
      "interventions": [
        {
          "name": "PurWet",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "FurFat",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurApo",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurPhl",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurClo",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "PurInf",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Smoliv",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "All Natural Medicine Clinic, LLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2000,
      "start_date": "2021-03-01",
      "completion_date": "2022-10-01",
      "has_results": false,
      "last_update_posted_date": "2021-05-26",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 1,
      "location_summary": "Rockville, Maryland",
      "locations": [
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04846010"
    },
    {
      "nct_id": "NCT05521880",
      "title": "Anchoring Sequential Intermittent Long Acting Antimicrobials With Medication for Opioid Use Disorder (MOUD) for Invasive Infections Related to Opioid Use",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Substance Use Disorders",
        "Infection, Soft Tissue",
        "Bacteremia",
        "Osteomyelitis Acute",
        "Septic Arthritis"
      ],
      "interventions": [
        {
          "name": "Oritavancin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "88 Years",
        "sex": "ALL",
        "summary": "18 Years to 88 Years"
      },
      "enrollment_count": 2,
      "start_date": "2024-07-15",
      "completion_date": "2025-05-23",
      "has_results": false,
      "last_update_posted_date": "2025-05-29",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05521880"
    },
    {
      "nct_id": "NCT02508584",
      "title": "Personalized Immunotherapeutic for Antibiotic-resistant Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Infection",
        "Immune Deficiency",
        "Hypogammaglobulinemia",
        "Septic Arthritis",
        "Mycoplasma Hominis"
      ],
      "interventions": [
        {
          "name": "anti-mycoplasma hominis antibodies",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "MALE",
        "summary": "Male only"
      },
      "enrollment_count": 1,
      "start_date": "2016-04-12",
      "completion_date": "2019-06-12",
      "has_results": false,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02508584"
    },
    {
      "nct_id": "NCT06489535",
      "title": "Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use Disorder",
        "Bloodstream Infection",
        "Osteomyelitis",
        "Endocarditis",
        "Septic Arthritis",
        "Epidural Abscess"
      ],
      "interventions": [
        {
          "name": "RETAIN",
          "type": "OTHER"
        },
        {
          "name": "Unrelated videos",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-01-06",
      "completion_date": "2026-05-11",
      "has_results": false,
      "last_update_posted_date": "2026-05-13",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06489535"
    },
    {
      "nct_id": "NCT00351273",
      "title": "Combination Antibiotic Treatment for Reactive Arthritis Caused by Chlamydia Bacteria",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Arthritis, Reactive",
        "Reiter Disease"
      ],
      "interventions": [
        {
          "name": "Doxycycline and Rifampin",
          "type": "DRUG"
        },
        {
          "name": "Azithromycin and Rifampin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 42,
      "start_date": "2006-05",
      "completion_date": "2008-09",
      "has_results": true,
      "last_update_posted_date": "2018-11-13",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 2,
      "location_summary": "Tampa, Florida • New Orleans, Louisiana",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00351273"
    },
    {
      "nct_id": "NCT00001375",
      "title": "The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthritis",
        "Arthritis, Reactive",
        "Arthritis, Rheumatoid",
        "Reiter's Disease",
        "Synovitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 500,
      "start_date": "1994-08",
      "completion_date": "2000-06",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-05-22T05:39:07.820Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001375"
    }
  ]
}