{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Disruptive+Behaviour+Disorders",
    "query": {
      "condition": "Severe Disruptive Behaviour Disorders"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Disruptive+Behaviour+Disorders&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T18:32:45.692Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00794040",
      "title": "A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mood Disorder",
        "Mental Disorder Diagnosed in Childhood",
        "Attention Deficit and Disruptive Behavior Disorder",
        "Attention Deficit Hyperactivity Disorder"
      ],
      "interventions": [
        {
          "name": "Add-on citalopram following optimized methylphenidate",
          "type": "DRUG"
        },
        {
          "name": "Add-on placebo following optimized methylphenidate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 103,
      "start_date": "2008-11-17",
      "completion_date": "2018-02-01",
      "has_results": true,
      "last_update_posted_date": "2019-05-07",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00794040"
    },
    {
      "nct_id": "NCT01105923",
      "title": "Study of an Intervention to Improve Problem List Accuracy and Use",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Attention Deficit Disorder With Hyperactivity",
        "Asthma",
        "COPD",
        "Breast Cancer",
        "Coronary Artery Disease",
        "Congestive Heart Failure",
        "Diabetes",
        "Glaucoma",
        "Hemophilia",
        "Hypertension",
        "Hyperthyroidism",
        "Hypothyroidism",
        "Myasthenia Gravis",
        "Osteoporosis",
        "Osteopenia",
        "Renal Failure",
        "Renal Insufficiency",
        "Sickle Cell Disease",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "MAPLE",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 140,
      "start_date": "2010-05",
      "completion_date": "2017-11",
      "has_results": false,
      "last_update_posted_date": "2015-02-02",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01105923"
    },
    {
      "nct_id": "NCT00796302",
      "title": "Treatment of Severe Childhood Aggression (The TOSCA Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Attention Deficit Disorder With Hyperactivity"
      ],
      "interventions": [
        {
          "name": "Methylphenidate HCl",
          "type": "DRUG"
        },
        {
          "name": "Risperidone",
          "type": "DRUG"
        },
        {
          "name": "Parent Management Training (PMT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Michael Aman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "6 Years to 12 Years"
      },
      "enrollment_count": 168,
      "start_date": "2008-08",
      "completion_date": "2012-11",
      "has_results": true,
      "last_update_posted_date": "2017-07-26",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 4,
      "location_summary": "Stony Brook, New York • Cleveland, Ohio • Columbus, Ohio + 1 more",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00796302"
    },
    {
      "nct_id": "NCT06792175",
      "title": "Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autism Spectrum Disorder",
        "Depression - Major Depressive Disorder",
        "Anxiety, Generalized",
        "Bipolar Disorder (BD)",
        "Attention Deficit Hyperactivity Disorder (ADHD)",
        "Schizophrenia Spectrum &Amp; Other Psychotic Disorders",
        "Post Traumatic Stress Disorder",
        "Obsessive Compulsive Disorder (OCD)"
      ],
      "interventions": [
        {
          "name": "Solicue Machine Learning Models",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Mercuria Machine Learning Models",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Psyrin Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "13 Years to 60 Years"
      },
      "enrollment_count": 500,
      "start_date": "2025-02-04",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2025-09-03",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 2,
      "location_summary": "Brookline, Massachusetts • Zanesville, Ohio",
      "locations": [
        {
          "city": "Brookline",
          "state": "Massachusetts"
        },
        {
          "city": "Zanesville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06792175"
    },
    {
      "nct_id": "NCT03261076",
      "title": "Reading Remediation and Outcomes in Detention",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Specific Learning Disorder (MeSH Unique ID: D000067559)",
        "Dyslexia (MeSH Unique ID: D004410)",
        "Conduct Disorder (MeSH Unique ID: D019955)"
      ],
      "interventions": [
        {
          "name": "Strategies Enhancing Reading in Older Underperf. Students",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "16 Years",
        "sex": "MALE",
        "summary": "14 Years to 16 Years · Male only"
      },
      "enrollment_count": 192,
      "start_date": "2018-05-14",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2022-03-02",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03261076"
    },
    {
      "nct_id": "NCT00025935",
      "title": "Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mood Disorder"
      ],
      "interventions": [
        {
          "name": "Lithium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "7 Years to 60 Years"
      },
      "enrollment_count": 2350,
      "start_date": "2002-01-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00025935"
    },
    {
      "nct_id": "NCT05357495",
      "title": "Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Disruptive Mood Dysregulation Disorder",
        "Attention Deficit Hyperactivity Disorder",
        "Normal Physiology"
      ],
      "interventions": [
        {
          "name": "Affective Posner fMRI frustration induction task",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "8 Years to 17 Years"
      },
      "enrollment_count": 0,
      "start_date": "2023-01-05",
      "completion_date": "2023-01-05",
      "has_results": false,
      "last_update_posted_date": "2023-01-10",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05357495"
    },
    {
      "nct_id": "NCT07540585",
      "title": "MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anxiety Disorders",
        "Stress Disorders, Post-Traumatic",
        "Pregnancy, High Risk",
        "Depressive Disorder, Major",
        "Pregnancy Complications",
        "ADHD - Attention Deficit Disorder With Hyperactivity"
      ],
      "interventions": [
        {
          "name": "Collaborative Mental Health Care Program (CMHCP)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 100 Years · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2026-06-01",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07540585"
    },
    {
      "nct_id": "NCT02795637",
      "title": "Study of the What the Body Does to the Drug in Subjects With Mild, Moderate, and Severe Liver Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Attention Deficit Hyperactivity Disorder (ADHD)",
        "Binge-Eating Disorder Disorder"
      ],
      "interventions": [
        {
          "name": "dasotraline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sumitomo Pharma America, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 44,
      "start_date": "2016-05",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2016-12-02",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 5,
      "location_summary": "Miami, Florida • Orlando, Florida • Atlanta, Georgia + 2 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02795637"
    },
    {
      "nct_id": "NCT00579267",
      "title": "Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depression",
        "Mania",
        "Anxiety Disorders",
        "Psychotic Disorder",
        "Alcohol Dependence",
        "Drug Dependence",
        "Eating Disorders",
        "Suicidality",
        "Dysthymia",
        "ADHD",
        "Tourettes Disorder",
        "Conduct Disorder",
        "Oppositional Defiant Disorder",
        "Pervasive Developmental Disorder"
      ],
      "interventions": [
        {
          "name": "MINI-KID",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 230,
      "start_date": "2004-02",
      "completion_date": "2008-01",
      "has_results": false,
      "last_update_posted_date": "2009-02-16",
      "last_synced_at": "2026-06-10T18:32:45.692Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00579267"
    }
  ]
}