{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Mental+Illness&page=35", "query": { "condition": "Severe Mental Illness", "page": 35 }, "page_size": 10 }, "pagination": { "page": 35, "page_size": 10, "total_count": 1853, "total_pages": 186, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Mental+Illness&page=36&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Mental+Illness&page=34&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-16T13:32:20.775Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07507370", "title": "CARED : A Novel Rapid Treatment Paradigm for Depression", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Intermittent Theta Burst Stimulation (iTBS)", "type": "DEVICE" }, { "name": "Transcranial Alternating Current Stimulation (tACS)", "type": "DEVICE" }, { "name": "Psychotherapy", "type": "BEHAVIORAL" }, { "name": "Sham (Placebo) Transcranial Alternating Current Stimulation (tACS)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE", "BEHAVIORAL" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 30, "start_date": "2026-04-14", "completion_date": "2028-07-01", "has_results": false, "last_update_posted_date": "2026-06-25", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT07507370" }, { "nct_id": "NCT02939560", "title": "TMS for Adults With Autism and Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Autism Spectrum Disorder", "Depression", "Depressive Disorder", "Major Depressive Disorder" ], "interventions": [ { "name": "NeuroStar® TMS device (Neuronetics, Atlanta, GA)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 13, "start_date": "2016-09", "completion_date": "2018-09-20", "has_results": true, "last_update_posted_date": "2019-10-01", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02939560" }, { "nct_id": "NCT04258618", "title": "Cognitive Behavioral Therapy for Insomnia with RTMS", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Depression", "Insomnia" ], "interventions": [ { "name": "CBT-I (Cognitive Behavioral Therapy for Insomnia) with rTMS", "type": "BEHAVIORAL" }, { "name": "Repetitive Transcranial Magnetic Stimulation", "type": "DEVICE" } ], "intervention_types": [ "BEHAVIORAL", "DEVICE" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 2, "start_date": "2020-08-04", "completion_date": "2021-01-31", "has_results": false, "last_update_posted_date": "2024-10-24", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04258618" }, { "nct_id": "NCT07780097", "title": "TRTME: Improving Outpatient Initiation of Medication for Opioid Use Disorder Following Hospitalization", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Opioid Use Disorder", "Opioid Use Disorder, Moderate", "Opioid Use Disorder, Severe" ], "interventions": [ { "name": "TRTME", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "T. John Winhusen, PhD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2026-08-19", "completion_date": "2027-02-28", "has_results": false, "last_update_posted_date": "2026-09-28", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT07780097" }, { "nct_id": "NCT06728774", "title": "Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Major Depressive Disorder (MDD)", "Cognitive Dysfunction" ], "interventions": [ { "name": "Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD)", "type": "BEHAVIORAL" }, { "name": "Goal-focused Supportive Contact", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Portland VA Medical Center", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 24, "start_date": "2025-05-01", "completion_date": "2026-06", "has_results": false, "last_update_posted_date": "2025-06-06", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT06728774" }, { "nct_id": "NCT06539169", "title": "FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Alpha-Thalassemia", "Beta-Thalassemia", "Amyloidosis", "Amyotrophic Lateral Sclerosis", "Creutzfeld-Jakob Disease", "Cystic Fibrosis", "Duchenne Muscular Dystrophy", "Early-Onset Alzheimer Disease", "Ehlers-Danlos Syndrome", "Huntington Disease", "Gaucher Disease", "GM1 Gangliosidosis", "Myasthenia Gravis", "Pompe Disease", "Sickle Cell Disease", "Transthyretin Amyloid Cardiomyopathy", "Rare Diseases" ], "interventions": [], "intervention_types": [], "sponsor": "xCures", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1000, "start_date": "2024-06-10", "completion_date": "2026-06-10", "has_results": false, "last_update_posted_date": "2024-11-14", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 1, "location_summary": "Los Altos, California", "locations": [ { "city": "Los Altos", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06539169" }, { "nct_id": "NCT04054596", "title": "Strategy Based Technique to Enhance Memory (STEM) for Improving New Learning and Memory (NLM) in Moderate to Severe TBI", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Traumatic Brain Injury", "Cognitive Impairment" ], "interventions": [ { "name": "SME", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Kessler Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 80, "start_date": "2017-12-01", "completion_date": "2024-07-31", "has_results": false, "last_update_posted_date": "2025-03-20", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 1, "location_summary": "East Hanover, New Jersey", "locations": [ { "city": "East Hanover", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT04054596" }, { "nct_id": "NCT00809770", "title": "Contingency Management of Psychostimulant Abuse in the Severely Mentally Ill", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Drug Abuse", "Schizophrenia", "Bipolar Disorder", "Major Depressive Disorder" ], "interventions": [ { "name": "Contingency Management", "type": "BEHAVIORAL" }, { "name": "Non Contingent Control Condition", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 176, "start_date": "2008-04", "completion_date": "2013-08", "has_results": false, "last_update_posted_date": "2016-11-08", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00809770" }, { "nct_id": "NCT02525978", "title": "Heart Rate Variability in Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Video Task", "type": "BEHAVIORAL" }, { "name": "Imaginal Task", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 8, "start_date": "2015-07", "completion_date": "2017-04-12", "has_results": false, "last_update_posted_date": "2019-09-20", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 3, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02525978" }, { "nct_id": "NCT04507243", "title": "Transcranial Direct Current Stimulation (tDCS) Therapy in Major Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Active - HD tDCS", "type": "DEVICE" }, { "name": "Sham - HD tDCS", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 72, "start_date": "2020-12-01", "completion_date": "2024-03-07", "has_results": false, "last_update_posted_date": "2024-04-30", "last_synced_at": "2026-10-16T13:32:20.775Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04507243" } ] }