{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Muscle+Atrophy",
    "query": {
      "condition": "Severe Muscle Atrophy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Muscle+Atrophy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-21T20:05:52.510Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07478172",
      "title": "Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neuromuscular Diseases (NMD)",
        "Amyotrophic Lateral Sclerosis",
        "Myasthenia Gravis",
        "Lambert-eaton Myasthenic Syndrome",
        "Primary Lateral Sclerosis",
        "Spinal Muscular Atrophy",
        "Charcot Marie Tooth Disease (CMT)",
        "Fascioscapulohumeral Muscular Dystrophy",
        "Inclusion Body Myositis",
        "Mitochondrial Myopathy",
        "Nemaline Myopathy",
        "Centronuclear Myopathy",
        "Postpolio Syndrome",
        "Pompe Disease (Late-onset)",
        "Chronic Inflammatory Demyelinating Polyneuropathy",
        "Hereditary Spastic Paraplegia",
        "Postural Orthostatic Tachycardia Syndrome (POTS)",
        "Progressive Muscular Atrophy"
      ],
      "interventions": [
        {
          "name": "Whole-body Electrical Muscle Stimulation Exercise",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2026-03-10",
      "completion_date": "2031-01-07",
      "has_results": false,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07478172"
    },
    {
      "nct_id": "NCT01403402",
      "title": "Congenital Muscle Disease Study of Patient and Family Reported Medical Information",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Muscular Dystrophy With ITGA7 (Integrin Alpha-7) Deficiency",
        "Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy and Abnormal Glycosylation of Dystroglycan With Severe Epilepsy)",
        "Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy With Fatty Liver and Infantile-onset Cataract Caused by TRAPPC11 Mutations)",
        "Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy With Hypoglycosylation of Dystroglycan)",
        "Alpha-Dystroglycanopathy (Congenital Muscular Dystrophy With Hypoglycosylation of Dystroglycan and Epilepsy)",
        "Alpha-Dystroglycanopathy (Dystroglycanopathy, Congenital With or Without Mental Retardation (Formerly MDC1C))",
        "Alpha-Dystroglycanopathy (Fukuyama CMD)",
        "Alpha-Dystroglycanopathy (LGMDR09 FKRP Related (Formerly LGMD2I))",
        "Alpha-Dystroglycanopathy (LGMDR11 POMT1 Related (Formerly LGMD2K))",
        "Alpha-Dystroglycanopathy (LGMDR13 FKTN Related (Formerly LGMD2M))",
        "Alpha-Dystroglycanopathy (LGMDR14 POMT2 Related (Formerly LGMD2N))",
        "Alpha-Dystroglycanopathy (LGMDR15 POMGnT1 Related (Formerly LGMD2O))",
        "Alpha-Dystroglycanopathy (LGMDR19 GMPPB Related (Formerly LGMD2T))",
        "Alpha-Dystroglycanopathy (LGMDR20 ISPD Related (Formerly LGMD2U))",
        "Alpha-Dystroglycanopathy (LGMDR24 POMGnT2 Related)",
        "Alpha-Dystroglycanopathy (Muscle Eye Brain Disease (MEB))",
        "Alpha-Dystroglycanopathy (Walker Warburg Syndrome (WWS))",
        "Choline Kinase B Receptor - CHKB",
        "Collagen VI Related Disorders",
        "Collagen XII Related Disorders",
        "Congenital Muscular Dystrophy Not Otherwise Specified (Including Merosin Positive)",
        "Congenital Muscular Dystrophy With Cataracts and Intellectual Disability (MDCCAID)",
        "Congenital Muscular Dystrophy With Joint Hyperlaxity",
        "Congenital Muscular Dystrophy With Rigid Spine Related to ACTA1",
        "Emery-Dreifuss Muscular Dystrophy",
        "GOLGA2-related Congenital Muscle Dystrophy With Brain Involvement",
        "LMNA Related Disorders",
        "Merosin Deficient CMD (Full or Partial)",
        "Nesprin Related MD (SYNE1)",
        "SELENON Related Disorders (Previously Known as SEPN1)",
        "SELENON Related Myopathy (Aka SEPN1)",
        "Telethonin CMD",
        "Congenital Myasthenic Syndrome",
        "Limb-Girdle Muscular Dystrophy",
        "LGMDD01 - DNAJB6 (Formerly LGMD1D)",
        "LGMDD05 - Collagen VI Related Bethlem Myopathy (Dominant)",
        "LGMDR07 - Telethonin (TCAP) Related (Formerly LGMD2G)",
        "LGMDR08 - TRIM Related (Formerly LGMD2H)",
        "LGMDR09 - FKRP Related (Formerly LGMD2I)",
        "LGMDR10 - Titin (TTN) Related (Formerly LGMD2J)",
        "LGMDR11 - POMT1 Related (Formerly LGMD2K)",
        "LGMDR13 - Fukutin (FKTN) Related (Formerly LGMD2M)",
        "LGMDR14 - POMT2 Related (Formerly LGMD2N)",
        "LGMDR15 - POMGnT1 Related (Formerly LGMD2O)",
        "LGMDR16 - DAG1 Related Dystroglycanopathy (Formerly LGMD2P)",
        "LGMDR17 - Plectin (PLEC) Related (Formerly LGMD2Q)",
        "LGMDR18 - TRAPPC11 Related (Formerly LGMD2S)",
        "LGMDR19 - GMPPB Related (Formerly LGMD2T)",
        "LGMDR20 - ISPD Related (Formerly LGMD2U)",
        "LGMDR22 - Collagen VI Related Bethlem Myopathy (Recessive)",
        "LGMDR23 - LAMA2 Related",
        "LGMDR24 - POMGnT2 Related"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Cure CMD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 4000,
      "start_date": "2009-09",
      "completion_date": "2029-09",
      "has_results": false,
      "last_update_posted_date": "2021-08-09",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 1,
      "location_summary": "Lakewood, California",
      "locations": [
        {
          "city": "Lakewood",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01403402"
    },
    {
      "nct_id": "NCT01717651",
      "title": "Muscle Atrophy in Patients With Severe Sepsis",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Severe Sepsis",
        "Respiratory Failure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2011-12",
      "completion_date": "2013-02",
      "has_results": false,
      "last_update_posted_date": "2016-01-18",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01717651"
    },
    {
      "nct_id": "NCT01028833",
      "title": "Effects of Power Mobility on Young Children With Severe Motor Impairments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cerebral Palsy",
        "Arthrogryposis",
        "Spinal Muscular Atrophy",
        "Other Central Nervous System or Musculoskeletal Disorders"
      ],
      "interventions": [
        {
          "name": "Power mobility",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Months",
        "maximum_age": "30 Months",
        "sex": "ALL",
        "summary": "14 Months to 30 Months"
      },
      "enrollment_count": 41,
      "start_date": "2008-11",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2016-01-14",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01028833"
    },
    {
      "nct_id": "NCT05062174",
      "title": "Breast Cancer BRCA1 Carriers: a Pilot Study",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "BRCA1 Mutation",
        "High-grade Serous Ovarian Cancer",
        "TNBC - Triple-Negative Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Mifepristone 200 MG",
          "type": "DRUG"
        },
        {
          "name": "Prophylactic mastectomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2021-11-01",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-12-15",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 2,
      "location_summary": "Carmel, Indiana • Indianapolis, Indiana",
      "locations": [
        {
          "city": "Carmel",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05062174"
    },
    {
      "nct_id": "NCT05035823",
      "title": "COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurologic Disorder",
        "Paralysis",
        "Paralysis; Stroke",
        "Amyotrophic Lateral Sclerosis",
        "Muscular Dystrophies",
        "Spinal Cord Injuries",
        "Stroke, Lacunar",
        "Stroke Brainstem",
        "Cervical Spinal Cord Injury",
        "Spinal Muscular Atrophy",
        "Tetraplegic; Paralysis",
        "Quadriplegia/Tetraplegia"
      ],
      "interventions": [
        {
          "name": "Motor Neuroprosthesis (MNP)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Synchron Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 6,
      "start_date": "2022-04-27",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2025-04-29",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 3,
      "location_summary": "Buffalo, New York • New York, New York • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05035823"
    },
    {
      "nct_id": "NCT06988176",
      "title": "Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Frailty",
        "Sarcopenia",
        "Sarcopenia in Elderly",
        "Muscle Strength",
        "Post Operative Complications",
        "Nutrition Assessment",
        "Risk Assessment",
        "Elderly (People Aged 65 or More)",
        "Hand Strength"
      ],
      "interventions": [
        {
          "name": "Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2025-06-19",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06988176"
    },
    {
      "nct_id": "NCT03655223",
      "title": "Early Check: Expanded Screening in Newborns",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spinal Muscular Atrophy",
        "Fragile X Syndrome",
        "Fragile X - Premutation",
        "Duchenne Muscular Dystrophy",
        "Hyperinsulinemic Hypoglycemia, Familial 1",
        "Diabetes Mellitus",
        "Adrenoleukodystrophy, Neonatal",
        "Medium-chain Acyl-CoA Dehydrogenase Deficiency",
        "Very Long Chain Acyl Coa Dehydrogenase Deficiency",
        "Beta-ketothiolase Deficiency",
        "Severe Combined Immunodeficiency Due to Adenosine Deaminase Deficiency",
        "Primary Hyperoxaluria Type 1",
        "Congenital Bile Acid Synthesis Defect Type 2",
        "Pyridoxine-Dependent Epilepsy",
        "Hereditary Fructose Intolerance",
        "Hypophosphatasia",
        "Hyperargininemia",
        "Mucopolysaccharidosis Type 6",
        "Argininosuccinic Aciduria",
        "Citrullinemia, Type I",
        "Wilson Disease",
        "Maple Syrup Urine Disease, Type 1A",
        "Maple Syrup Urine Disease, Type 1B",
        "Biotinidase Deficiency",
        "Neonatal Severe Primary Hyperparathyroidism",
        "Intrinsic Factor Deficiency",
        "Usher Syndrome Type 1D/F Digenic (Diagnosis)",
        "Cystic Fibrosis",
        "Stickler Syndrome Type 2",
        "Stickler Syndrome Type 1",
        "Alport Syndrome, Autosomal Recessive",
        "Alport Syndrome, X-Linked",
        "Carbamoyl Phosphate Synthetase I Deficiency Disease",
        "Carnitine Palmitoyl Transferase 1A Deficiency",
        "Carnitine Palmitoyltransferase II Deficiency",
        "Cystinosis",
        "Chronic Granulomatous Disease",
        "Cerebrotendinous Xanthomatoses",
        "Maple Syrup Urine Disease, Type 2",
        "Severe Combined Immunodeficiency Due to DCLRE1C Deficiency",
        "Thyroid Dyshormonogenesis 6",
        "Thyroid Dyshormonogenesis 5",
        "Supravalvar Aortic Stenosis",
        "Factor X Deficiency",
        "Hemophilia A",
        "Hemophilia B",
        "Tyrosinemia, Type I",
        "Fructose 1,6 Bisphosphatase Deficiency",
        "Glycogen Storage Disease Type I",
        "G6PD Deficiency",
        "Glycogen Storage Disease II",
        "Galactokinase Deficiency",
        "Mucopolysaccharidosis Type IV A",
        "Galactosemias",
        "Guanidinoacetate Methyltransferase Deficiency",
        "Agat Deficiency",
        "Glutaryl-CoA Dehydrogenase Deficiency",
        "Gtp Cyclohydrolase I Deficiency",
        "Hyperinsulinism-Hyperammonemia Syndrome",
        "Primary Hyperoxaluria Type 2",
        "3-Hydroxyacyl-CoA Dehydrogenase Deficiency",
        "Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency",
        "Mitochondrial Trifunctional Protein Deficiency",
        "Sickle Cell Disease",
        "Beta-Thalassemia",
        "Holocarboxylase Synthetase Deficiency",
        "3-Hydroxy-3-Methylglutaric Aciduria",
        "Primary Hyperoxaluria Type 3",
        "Hermansky-Pudlak Syndrome 1",
        "Hermansky-Pudlak Syndrome 4",
        "Apparent Mineralocorticoid Excess",
        "HSDB",
        "CBAS1",
        "Mucopolysaccharidosis Type 2",
        "Mucopolysaccharidosis Type 1",
        "Severe Combined Immunodeficiency, X Linked",
        "Severe Combined Immunodeficiency Due to IL-7Ralpha Deficiency",
        "Diabetes Mellitus, Permanent Neonatal",
        "Isovaleric Acidemia",
        "Severe Combined Immunodeficiency T-Cell Negative B-Cell Positive Due to Janus Kinase-3 Deficiency (Disorder)",
        "Jervell and Lange-Nielsen Syndrome 2",
        "Hyperinsulinemic Hypoglycemia, Familial, 2",
        "Diabetes Mellitus, Permanent Neonatal, With Neurologic Features",
        "Jervell and Lange-Nielsen Syndrome 1",
        "Lysosomal Acid Lipase Deficiency",
        "CblF",
        "3-Methylcrotonyl CoA Carboxylase 1 Deficiency",
        "3-Methylcrotonyl CoA Carboxylase 2 Deficiency",
        "Waardenburg Syndrome Type 2A",
        "Methylmalonic Aciduria cblA Type",
        "Methylmalonic Aciduria cblB Type",
        "Methylmalonic Aciduria and Homocystinuria Type cblC",
        "MAHCD",
        "Methylmalonic Aciduria Due to Methylmalonyl-CoA Mutase Deficiency",
        "Congenital Disorder of Glycosylation Type 1B",
        "Mthfr Deficiency",
        "Methylcobalamin Deficiency Type Cbl G (Disorder)",
        "Methylcobalamin Deficiency Type cblE",
        "Usher Syndrome, Type 1B",
        "N-acetylglutamate Synthase Deficiency",
        "Ornithine Transcarbamylase Deficiency",
        "Phenylketonurias",
        "Waardenburg Syndrome Type 1",
        "Congenital Hypothyroidism",
        "Propionic Acidemia",
        "Usher Syndrome, Type 1F",
        "Pancreatic Agenesis 1",
        "Hereditary Hypophosphatemic Rickets",
        "Glycogen Storage Disease IXB",
        "Glycogen Storage Disease IXC",
        "MOWS",
        "Epilepsy, Early-Onset, Vitamin B6-Dependent",
        "Pyridoxal Phosphate-Responsive Seizures",
        "Pituitary Hormone Deficiency, Combined, 1",
        "Ptsd",
        "Dihydropteridine Reductase Deficiency",
        "Severe Combined Immunodeficiency Due to RAG1 Deficiency",
        "Severe Combined Immunodeficiency Due to RAG2 Deficiency",
        "Retinoblastoma",
        "Multiple Endocrine Neoplasia Type 2B",
        "Pseudohypoaldosteronism, Type I",
        "Liddle Syndrome",
        "Biotin-Responsive Basal Ganglia Disease",
        "SCD",
        "DIAR1",
        "GSD1C",
        "Acrodermatitis Enteropathica",
        "Thyroid Dyshormonogenesis 1",
        "Riboflavin Transporter Deficiency",
        "Waardenburg Syndrome, Type 2E",
        "SRD",
        "Congenital Lipoid Adrenal Hyperplasia Due to STAR Deficiency",
        "Barth Syndrome",
        "Adrenocorticotropic Hormone Deficiency",
        "Transcobalamin II Deficiency",
        "Thyroid Dyshormonogenesis 3",
        "Segawa Syndrome, Autosomal Recessive",
        "Autosomal Recessive Nonsyndromic Hearing Loss",
        "Thyroid Dyshormonogenesis 2A",
        "Congenital Isolated Thyroid Stimulating Hormone Deficiency",
        "Hypothyroidism Due to TSH Receptor Mutations",
        "Usher Syndrome Type 1C",
        "Usher Syndrome Type 1G (Diagnosis)",
        "Von Willebrand Disease, Type 3",
        "Combined Immunodeficiency Due to ZAP70 Deficiency",
        "Adenine Phosphoribosyltransferase Deficiency",
        "Metachromatic Leukodystrophy",
        "Canavan Disease",
        "Menkes Disease",
        "Carbonic Anhydrase VA Deficiency",
        "Developmental and Epileptic Encephalopathy 2",
        "17 Alpha-Hydroxylase Deficiency",
        "Smith-Lemli-Opitz Syndrome",
        "Krabbe Disease",
        "Glutathione Synthetase Deficiency",
        "Mucopolysaccharidosis Type 7",
        "Rett Syndrome",
        "Molybdenum Cofactor Deficiency, Type A",
        "Niemann-Pick Disease, Type C1",
        "Niemann-Pick Disease Type C2",
        "Ornithine Aminotransferase Deficiency",
        "3-Phosphoglycerate Dehydrogenase Deficiency",
        "Leber Congenital Amaurosis 2",
        "Dravet Syndrome",
        "Mucopolysaccharidosis Type 3 A",
        "Ornithine Translocase Deficiency",
        "Carnitine-acylcarnitine Translocase Deficiency",
        "Glucose Transporter Type 1 Deficiency Syndrome",
        "Creatine Transporter Deficiency",
        "Niemann-Pick Disease Type A",
        "Pitt Hopkins Syndrome",
        "Tuberous Sclerosis 1",
        "Tuberous Sclerosis 2",
        "Ataxia With Isolated Vitamin E Deficiency",
        "Angelman Syndrome",
        "Prader-Willi Syndrome",
        "Homocystinuria",
        "Permanent Neonatal Diabetes Mellitus",
        "Transient Neonatal Diabetes Mellitus",
        "Factor VII Deficiency",
        "Glycogen Storage Disease Type IXA1",
        "Glycogen Storage Disease, Type IXA2",
        "Glycogen Storage Disease IC",
        "Glycogen Storage Disease Type IB",
        "Central Hypoventilation Syndrome With or Without Hirschsprung Disease"
      ],
      "interventions": [
        {
          "name": "Confirmatory Testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "RTI International",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "31 Days",
        "sex": "ALL",
        "summary": "1 Day to 31 Days"
      },
      "enrollment_count": 30000,
      "start_date": "2018-10-15",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 1,
      "location_summary": "Research Triangle Park, North Carolina",
      "locations": [
        {
          "city": "Research Triangle Park",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03655223"
    },
    {
      "nct_id": "NCT01497678",
      "title": "Musculotendinous Tissue Unit Repair and Reinforcement (MTURR) Coordinating Center",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Injury",
        "Muscle Injury",
        "Tendon Injury",
        "Soft Tissue Injury",
        "Extremity Injury"
      ],
      "interventions": [
        {
          "name": "Extracellular Matrix",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2013-03",
      "completion_date": "2014-11",
      "has_results": false,
      "last_update_posted_date": "2016-10-21",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01497678"
    },
    {
      "nct_id": "NCT04357184",
      "title": "BFRT for Severe Lower Extremity Muscle Atrophy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Muscle Atrophy",
        "Muscle Weakness"
      ],
      "interventions": [
        {
          "name": "Blood flow restriction training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cincinnati Sportsmedicine Research and Education Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100,
      "start_date": "2020-04-14",
      "completion_date": "2022-02-15",
      "has_results": false,
      "last_update_posted_date": "2022-02-16",
      "last_synced_at": "2026-07-21T20:05:52.510Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04357184"
    }
  ]
}