{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Neurologic+Injury",
    "query": {
      "condition": "Severe Neurologic Injury"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 183,
    "total_pages": 19,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Neurologic+Injury&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T23:57:33.792Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07042815",
      "title": "Long-term Follow-up for Epidural Stimulation in SCI",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "SCI - Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Epidural Stimulation Programs",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Kessler Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 91,
      "start_date": "2025-01-13",
      "completion_date": "2028-08",
      "has_results": false,
      "last_update_posted_date": "2025-06-29",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 1,
      "location_summary": "West Orange, New Jersey",
      "locations": [
        {
          "city": "West Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07042815"
    },
    {
      "nct_id": "NCT04051242",
      "title": "Enhanced Bioscaffold for Volumetric Muscle Loss",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Loss"
      ],
      "interventions": [
        {
          "name": "XenMatrix™ AB Surgical Graft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "J. Peter Rubin, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 10,
      "start_date": "2020-02-10",
      "completion_date": "2024-01-24",
      "has_results": true,
      "last_update_posted_date": "2025-04-25",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04051242"
    },
    {
      "nct_id": "NCT01253746",
      "title": "Genetics of Neural Tube Defects",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neural Tube Defects"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "John P. Hussman Institute for Human Genomics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 6000,
      "start_date": "2009-04",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2010-12-03",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01253746"
    },
    {
      "nct_id": "NCT04032301",
      "title": "Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Post-Traumatic Stress Disorders",
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 67,
      "start_date": "2019-09-30",
      "completion_date": "2024-11-10",
      "has_results": false,
      "last_update_posted_date": "2025-06-27",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04032301"
    },
    {
      "nct_id": "NCT00947232",
      "title": "Motivational Interviewing to Increase Physical Activity to Treat Depression in People Aging With MS or SCI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis",
        "Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Motivational interviewing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 123,
      "start_date": "2009-10",
      "completion_date": "2013-03",
      "has_results": false,
      "last_update_posted_date": "2017-05-05",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00947232"
    },
    {
      "nct_id": "NCT03111277",
      "title": "MR Guided Focused Ultrasound for Treatment of Neuropathic Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Neuropathic Pain Due to Radiculopathy or Radicular Injury",
        "Spinal Cord Injuries",
        "Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "Experimental: ExAblate Transcranial treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2017-09-15",
      "completion_date": "2022-10-09",
      "has_results": false,
      "last_update_posted_date": "2022-10-12",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03111277"
    },
    {
      "nct_id": "NCT07331324",
      "title": "The Coma Family Program (COMA-F): A Resilience Program for Caregivers of Patients With Severe Acute Brain Injury",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caregiver Distress",
        "Emotional Distress",
        "Caregivers",
        "Resilience",
        "Coma",
        "Brain Injury"
      ],
      "interventions": [
        {
          "name": "Coma Family Program 1",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Coma Family Program 2",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2026-05",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 3,
      "location_summary": "Baltimore, Maryland • Boston, Massachusetts • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07331324"
    },
    {
      "nct_id": "NCT00488280",
      "title": "Restoring Walking in Non-ambulatory Children With Severe Chronic Spinal Cord Injury (SCI) (Kids STEP Study)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spinal Cord Injury (SCI)"
      ],
      "interventions": [
        {
          "name": "Locomotor Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "3 Years to 13 Years"
      },
      "enrollment_count": 7,
      "start_date": "2007-02",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2024-11-08",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00488280"
    },
    {
      "nct_id": "NCT02957461",
      "title": "Validation of Brain Function Assessment Algorithm for mTBI/Concussion in College Athletes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Brain Injuries, Traumatic",
        "Concussion, Mild",
        "Concussion, Brain",
        "Concussion, Severe",
        "Concussion, Intermediate"
      ],
      "interventions": [
        {
          "name": "BrainScope Ahead 200iD",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "BrainScope Company, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "18 Years to 25 Years"
      },
      "enrollment_count": 420,
      "start_date": "2017-02-03",
      "completion_date": "2018-03-02",
      "has_results": false,
      "last_update_posted_date": "2019-05-23",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 8,
      "location_summary": "Fayetteville, Arkansas • Storrs, Connecticut • Tampa, Florida + 5 more",
      "locations": [
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Storrs",
          "state": "Connecticut"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "East Lansing",
          "state": "Michigan"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02957461"
    },
    {
      "nct_id": "NCT07560631",
      "title": "SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury (TBI) Patients",
        "Severe Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "SeeMe Multimodal Auditory Command Protocol",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "22 Years to 85 Years"
      },
      "enrollment_count": 80,
      "start_date": "2026-03-30",
      "completion_date": "2029-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-07-23T23:57:33.792Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07560631"
    }
  ]
}