{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Preeclampsia",
    "query": {
      "condition": "Severe Preeclampsia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 37,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Severe+Preeclampsia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T13:58:09.041Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04070573",
      "title": "Low Doses of Aspirin in the Prevention of Preeclampsia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Preeclampsia"
      ],
      "interventions": [
        {
          "name": "acetylsalicylic acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 400,
      "start_date": "2019-10-21",
      "completion_date": "2025-01-23",
      "has_results": true,
      "last_update_posted_date": "2025-03-13",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04070573"
    },
    {
      "nct_id": "NCT03872336",
      "title": "Acute Labetalol Use in Preeclampsia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preeclampsia With Severe Features"
      ],
      "interventions": [
        {
          "name": "Experimental labetalol dose",
          "type": "DRUG"
        },
        {
          "name": "Current standard of care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Albany Medical College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 15,
      "start_date": "2019-02-18",
      "completion_date": "2020-07-20",
      "has_results": false,
      "last_update_posted_date": "2020-07-22",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03872336"
    },
    {
      "nct_id": "NCT04725812",
      "title": "Complement Regulation to Undo Systemic Harm in Preeclampsia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Preeclampsia",
        "Severe Preeclampsia",
        "Eculizumab",
        "HELLP",
        "HELLP Syndrome",
        "HELLP Syndrome Second Trimester",
        "Pregnancy Related",
        "AHUS",
        "PNH",
        "Complement Regulatory Factor Defect",
        "Complement Abnormality",
        "HELLP Syndrome Third Trimester"
      ],
      "interventions": [
        {
          "name": "Eculizumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "13 Years and older · Female only"
      },
      "enrollment_count": 2,
      "start_date": "2021-09-13",
      "completion_date": "2021-12-07",
      "has_results": true,
      "last_update_posted_date": "2023-11-29",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04725812"
    },
    {
      "nct_id": "NCT07430254",
      "title": "Finger Plethysmography to Predict Fluid Responsiveness in Healthy Pregnancy and Severe Preeclampsia",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pre-Eclampsia, Severe",
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "Noninvasive finger plethysmographic cardiac output monitoring",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Standard transthoracic echocardiographic assessment",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 88,
      "start_date": "2026-07-01",
      "completion_date": "2028-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07430254"
    },
    {
      "nct_id": "NCT04236258",
      "title": "Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum Period",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypertension in Pregnancy",
        "Preeclampsia Severe",
        "Gestational Hypertension",
        "Postpartum Preeclampsia",
        "Postpartum"
      ],
      "interventions": [
        {
          "name": "NIFEdipine ER",
          "type": "DRUG"
        },
        {
          "name": "Enalapril",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 94,
      "start_date": "2020-01-24",
      "completion_date": "2021-06-30",
      "has_results": true,
      "last_update_posted_date": "2022-11-30",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04236258"
    },
    {
      "nct_id": "NCT07478055",
      "title": "Biomarkers in Management of Post Partum Preeclampsia",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preeclampsia Severe",
        "Preeclampsia Postpartum"
      ],
      "interventions": [
        {
          "name": "Magnesium Sulfate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexander Harrison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2026-06",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-01",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07478055"
    },
    {
      "nct_id": "NCT00719654",
      "title": "Alterations in the Plasma Proteome of Early-Onset Severe Preeclampsia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preeclampsia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 316,
      "start_date": "2007-08",
      "completion_date": "2012-04-09",
      "has_results": false,
      "last_update_posted_date": "2018-05-18",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00719654"
    },
    {
      "nct_id": "NCT05096728",
      "title": "Nifedipine Dosing Daily vs Twice a Day for Pre-eclampsia With Severe Features (NOPPI)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Preeclampsia With Severe Features"
      ],
      "interventions": [
        {
          "name": "Nifedipine XL",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 56,
      "start_date": "2021-12-01",
      "completion_date": "2023-12-15",
      "has_results": false,
      "last_update_posted_date": "2023-12-22",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05096728"
    },
    {
      "nct_id": "NCT06310720",
      "title": "Postpartum Video Education in High Risk Populations",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postpartum Hemorrhage",
        "Postpartum Depression",
        "Postpartum Sepsis",
        "Postpartum Preeclampsia",
        "Patient Empowerment",
        "Patient Education",
        "Postpartum Care"
      ],
      "interventions": [
        {
          "name": "Video Education",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 150,
      "start_date": "2024-05-09",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-08-28",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06310720"
    },
    {
      "nct_id": "NCT04392375",
      "title": "Nifedipine XL Versus Placebo for the Treatment of Preeclampsia With Severe Features During Induction of Labor",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Preeclampsia Severe"
      ],
      "interventions": [
        {
          "name": "Nifedipine 30 MG",
          "type": "DRUG"
        },
        {
          "name": "Placebos",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 110,
      "start_date": "2020-06-09",
      "completion_date": "2022-05-10",
      "has_results": true,
      "last_update_posted_date": "2023-07-24",
      "last_synced_at": "2026-07-22T13:58:09.041Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04392375"
    }
  ]
}