{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Sex+Chromosome+Aberrations",
    "query": {
      "condition": "Sex Chromosome Aberrations"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Sex+Chromosome+Aberrations&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T08:40:26.158Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06373861",
      "title": "Generating Advancements Through Longitudinal Analysis in X and Y Variations (GALAXY)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sex Chromosome Aneuploidy"
      ],
      "interventions": [
        {
          "name": "no intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "0 Days to 100 Years"
      },
      "enrollment_count": 5000,
      "start_date": "2022-04-28",
      "completion_date": "2037-04",
      "has_results": false,
      "last_update_posted_date": "2024-04-18",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06373861"
    },
    {
      "nct_id": "NCT01585831",
      "title": "Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Klinefelter Syndrome",
        "XXY Syndrome"
      ],
      "interventions": [
        {
          "name": "Testosterone gel 1%",
          "type": "DRUG"
        },
        {
          "name": "Placebo gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "18 Years",
        "sex": "MALE",
        "summary": "8 Years to 18 Years · Male only"
      },
      "enrollment_count": 48,
      "start_date": "2012-03",
      "completion_date": "2017-10",
      "has_results": true,
      "last_update_posted_date": "2021-08-10",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01585831"
    },
    {
      "nct_id": "NCT01661010",
      "title": "The Clinical Study of Sex Chromosome Variants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Male Factor Infertility",
        "Female Factor Infertility"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Human Genome Research Institute (NHGRI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 112,
      "start_date": "2012-07-30",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-06-11",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01661010"
    },
    {
      "nct_id": "NCT00471731",
      "title": "Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Turner Syndrome",
        "Ovarian Failure, Premature",
        "Sex Chromosome Aberrations",
        "Menopause",
        "Perimenopause"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 72,
      "start_date": "2007-05-07",
      "completion_date": "2014-11-13",
      "has_results": false,
      "last_update_posted_date": "2018-02-14",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00471731"
    },
    {
      "nct_id": "NCT01545674",
      "title": "Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Trisomy 13",
        "Trisomy 18",
        "Trisomy 21",
        "Aneuploidy"
      ],
      "interventions": [
        {
          "name": "Blood Draw",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Natera, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 937,
      "start_date": "2012-01",
      "completion_date": "2023-03",
      "has_results": false,
      "last_update_posted_date": "2023-03-23",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 24,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • San Francisco, California + 16 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01545674"
    },
    {
      "nct_id": "NCT02109770",
      "title": "Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Microdeletion Syndromes",
        "Trisomy 21",
        "Trisomy 18",
        "Trisomy 13",
        "Sex Chromosome Abnormalities"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Natera, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 216,
      "start_date": "2012-10",
      "completion_date": "2019-08",
      "has_results": false,
      "last_update_posted_date": "2019-08-26",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 2,
      "location_summary": "San Carlos, California • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "San Carlos",
          "state": "California"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02109770"
    },
    {
      "nct_id": "NCT01574781",
      "title": "Non-invasive Prenatal Diagnostic Validation Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chromosome 13 Aneuploidy",
        "Chromosome 18 Aneuploidy",
        "Chromosome 21 Aneuploidy",
        "Sex Chromosome Aberrations",
        "Other Microdeletions"
      ],
      "interventions": [
        {
          "name": "Blood draw",
          "type": "PROCEDURE"
        },
        {
          "name": "Cheek swab/Saliva Sampling",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Natera, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1781,
      "start_date": "2011-09",
      "completion_date": "2013-04",
      "has_results": false,
      "last_update_posted_date": "2013-07-02",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 1,
      "location_summary": "Redwood City, California",
      "locations": [
        {
          "city": "Redwood City",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01574781"
    },
    {
      "nct_id": "NCT00891852",
      "title": "Non-Invasive Determination of Fetal Chromosome Abnormalities",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Down Syndrome (Trisomy 21)",
        "Edward's Syndrome (Trisomy 18)",
        "Patau Syndrome (Trisomy 13)",
        "Klinefelter Syndrome (47, XXY)",
        "and Other Chromosome",
        "Abnormalities."
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Lenetix Medical Screening Laboratory",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 1000,
      "start_date": "2009-01",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2009-05-01",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 7,
      "location_summary": "Rockville, Maryland • Moristown, New Jersey • Mineola, New York + 3 more",
      "locations": [
        {
          "city": "Rockville",
          "state": "Maryland"
        },
        {
          "city": "Moristown",
          "state": "New Jersey"
        },
        {
          "city": "Mineola",
          "state": "New York"
        },
        {
          "city": "New Hyde Park",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00891852"
    },
    {
      "nct_id": "NCT07643896",
      "title": "The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pregnant Individuals",
        "Aneuploidy",
        "Down Syndrome (Trisomy 21)",
        "22q11.2 Deletion Syndrome",
        "Trisomy 13",
        "Trisomy 18",
        "Sex Chromosome Abnormalities"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "BillionToOne Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 1000,
      "start_date": "2026-01-10",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-12",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 6,
      "location_summary": "Phoenix, Arizona • West Covina, California • Sarasota, Florida + 3 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "West Covina",
          "state": "California"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07643896"
    },
    {
      "nct_id": "NCT02381457",
      "title": "SNP-based Microdeletion and Aneuploidy RegisTry (SMART)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "22q11 Deletion Syndrome",
        "DiGeorge Syndrome",
        "Trisomy 21",
        "Trisomy 18",
        "Trisomy 13",
        "Monosomy X",
        "Sex Chromosome Abnormalities",
        "Cri-du-Chat Syndrome",
        "Angelman Syndrome",
        "Prader-Willi Syndrome",
        "1p36 Deletion Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Natera, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "48 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 48 Years · Female only"
      },
      "enrollment_count": 20960,
      "start_date": "2015-04",
      "completion_date": "2020-06",
      "has_results": false,
      "last_update_posted_date": "2021-01-29",
      "last_synced_at": "2026-07-23T08:40:26.158Z",
      "location_count": 16,
      "location_summary": "San Francisco, California • Camden, New Jersey • Mount Laurel, New Jersey + 10 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Camden",
          "state": "New Jersey"
        },
        {
          "city": "Mount Laurel",
          "state": "New Jersey"
        },
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        },
        {
          "city": "Garden City",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02381457"
    }
  ]
}