{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Shy-Drager+Syndrome&page=2", "query": { "condition": "Shy-Drager Syndrome", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Shy-Drager+Syndrome&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-05-22T08:15:45.129Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07081841", "title": "AB-1005 Long-Term Follow-up Study", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Parkinson's Disease", "Multiple System Atrophy, Parkinson Variant" ], "interventions": [ { "name": "Observation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "AskBio Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 132, "start_date": "2025-09-04", "completion_date": "2038-03-30", "has_results": false, "last_update_posted_date": "2025-10-02", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 2, "location_summary": "San Francisco, California • Columbus, Ohio", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT07081841" }, { "nct_id": "NCT00223717", "title": "Treatment of Supine Hypertension in Autonomic Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Clonidine", "type": "DRUG" }, { "name": "Nitroglycerin transdermal", "type": "DRUG" }, { "name": "Dipyridamole/ Aspirin (Aggrenox)", "type": "DRUG" }, { "name": "Desmopressin (DDAVP)", "type": "DRUG" }, { "name": "Sildenafil", "type": "DRUG" }, { "name": "Nifedipine", "type": "DRUG" }, { "name": "Hydralazine", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Bosentan", "type": "DRUG" }, { "name": "Diltiazem", "type": "DRUG" }, { "name": "Eplerenone", "type": "DRUG" }, { "name": "guanfacine", "type": "DRUG" }, { "name": "L-arginine", "type": "DIETARY_SUPPLEMENT" }, { "name": "captopril", "type": "DRUG" }, { "name": "carbidopa", "type": "DRUG" }, { "name": "losartan", "type": "DRUG" }, { "name": "metoprolol tartrate", "type": "DRUG" }, { "name": "nebivolol hydrochloride", "type": "DRUG" }, { "name": "prazosin hydrochloride", "type": "DRUG" }, { "name": "tamsulosin hydrochloride", "type": "DRUG" }, { "name": "Head-up tilt.", "type": "OTHER" }, { "name": "aliskiren", "type": "DRUG" }, { "name": "Local heat stress", "type": "OTHER" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 152, "start_date": "2001-01", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2017-10-13", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00223717" }, { "nct_id": "NCT03446807", "title": "Safety and Efficacy of Droxidopa for Fatigue in Patients With Parkinsonism", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Parkinson Disease", "Multiple System Atrophy", "Progressive Supranuclear Palsy" ], "interventions": [ { "name": "Droxidopa", "type": "DRUG" }, { "name": "Placebo Oral Tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Loma Linda University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 0, "start_date": "2021-12", "completion_date": "2023-07-01", "has_results": false, "last_update_posted_date": "2022-03-02", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 1, "location_summary": "Loma Linda, California", "locations": [ { "city": "Loma Linda", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03446807" }, { "nct_id": "NCT01316666", "title": "Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Orthostatic Hypotension", "Pure Autonomic Failure", "Multiple System Atrophy", "Parkinson's Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 50, "start_date": "2011-03", "completion_date": "2016-12", "has_results": false, "last_update_posted_date": "2017-01-06", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 4, "location_summary": "Boston, Massachusetts • Rochester, Minnesota • New York, New York + 1 more", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Rochester", "state": "Minnesota" }, { "city": "New York", "state": "New York" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01316666" }, { "nct_id": "NCT00059033", "title": "Evaluation of Primary Chronic Autonomic Failure", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Autonomic Nervous System Diseases" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 325, "start_date": "2003-04-10", "completion_date": "2018-10-30", "has_results": false, "last_update_posted_date": "2019-12-12", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00059033" }, { "nct_id": "NCT00633880", "title": "Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Symptomatic Neurogenic Orthostatic Hypotension (NOH)", "Non-diabetic Neuropathy", "Primary Autonomic Failure", "Dopamine Beta Hydroxylase Deficiency" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Droxidopa", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Chelsea Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 181, "start_date": "2008-01", "completion_date": "2009-09", "has_results": true, "last_update_posted_date": "2014-05-20", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 44, "location_summary": "Birmingham, Alabama • Litchfield Park, Arizona • Phoenix, Arizona + 39 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Litchfield Park", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Fountain Valley", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00633880" }, { "nct_id": "NCT07197866", "title": "An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Multiple System Atrophy" ], "interventions": [ { "name": "TEV-56286", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Teva Branded Pharmaceutical Products R&D LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 200, "start_date": "2025-09-30", "completion_date": "2029-05-17", "has_results": false, "last_update_posted_date": "2026-05-12", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 5, "location_summary": "Boca Raton, Florida • Tampa, Florida • New York, New York + 1 more", "locations": [ { "city": "Boca Raton", "state": "Florida" }, { "city": "Tampa", "state": "Florida" }, { "city": "New York", "state": "New York" }, { "city": "New York", "state": "New York" }, { "city": "Spokane", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT07197866" }, { "nct_id": "NCT00738062", "title": "Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Neurogenic Orthostatic Hypotension", "Non-Diabetic Autonomic Neuropathy", "Multiple System Atrophy", "Dopamine Beta Hydroxylase Deficiency" ], "interventions": [ { "name": "Droxidopa", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Chelsea Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 103, "start_date": "2008-01", "completion_date": "2010-12", "has_results": true, "last_update_posted_date": "2014-05-16", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 44, "location_summary": "Birmingham, Alabama • Litchfield Park, Arizona • Phoenix, Arizona + 39 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Litchfield Park", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Fountain Valley", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00738062" }, { "nct_id": "NCT05826457", "title": "North American Prodromal Synucleinopathy Consortium Stage 2", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "REM Sleep Behavior Disorder", "Parkinson Disease", "Lewy Body Dementia", "Dementia With Lewy Bodies", "Multiple System Atrophy", "REM Sleep Parasomnias" ], "interventions": [], "intervention_types": [], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 500, "start_date": "2022-08-12", "completion_date": "2028-05-01", "has_results": false, "last_update_posted_date": "2026-05-13", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 8, "location_summary": "Los Angeles, California • Redwood City, California • Atlanta, Georgia + 5 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Redwood City", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05826457" }, { "nct_id": "NCT01119417", "title": "The Role of Endothelin in the Supine Hypertension of Autonomic Failure", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hypertension", "Pure Autonomic Failure", "Multiple System Atrophy" ], "interventions": [ { "name": "BQ123", "type": "DRUG" }, { "name": "Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 0, "start_date": "2010-05", "completion_date": "2021-05", "has_results": false, "last_update_posted_date": "2021-10-05", "last_synced_at": "2026-05-22T08:15:45.129Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01119417" } ] }