{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Sick+Sinus+Syndrome",
    "query": {
      "condition": "Sick Sinus Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 22,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Sick+Sinus+Syndrome&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T07:11:06.835Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00355797",
      "title": "Effectiveness of Pacemaker With Closed Loop Stimulation Compared to Pacemakers With and Without Standard Rate Response",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Bradycardia"
      ],
      "interventions": [
        {
          "name": "Closed Loop Stimulation (CLS)",
          "type": "DEVICE"
        },
        {
          "name": "Standard Rate Adaptive (R) Technology",
          "type": "DEVICE"
        },
        {
          "name": "Non-rate adaptive (DDD) pacing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biotronik, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1491,
      "start_date": "2006-05",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2012-12-20",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 99,
      "location_summary": "Albertville, Alabama • Gadsden, Alabama • Jasper, Alabama + 82 more",
      "locations": [
        {
          "city": "Albertville",
          "state": "Alabama"
        },
        {
          "city": "Gadsden",
          "state": "Alabama"
        },
        {
          "city": "Gadsden",
          "state": "Alabama"
        },
        {
          "city": "Jasper",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00355797"
    },
    {
      "nct_id": "NCT01781078",
      "title": "ImageReady(TM) MR Conditional Pacing System Clinical Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bradycardia",
        "Sinus Node Dysfunction"
      ],
      "interventions": [
        {
          "name": "MRI",
          "type": "RADIATION"
        },
        {
          "name": "ImageReady System implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 363,
      "start_date": "2013-02",
      "completion_date": "2019-09-11",
      "has_results": true,
      "last_update_posted_date": "2019-12-03",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 29,
      "location_summary": "Mesa, Arizona • Los Angeles, California • San Francisco, California + 26 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01781078"
    },
    {
      "nct_id": "NCT00627328",
      "title": "The Atrial High Rate Episodes in Pacemaker Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arrhythmia",
        "Atrial Fibrillation",
        "Atrioventricular Block",
        "Bradycardia",
        "Sick Sinus Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Medtronic Cardiac Rhythm and Heart Failure",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 427,
      "start_date": "2000-07",
      "completion_date": "2004-09",
      "has_results": false,
      "last_update_posted_date": "2008-03-03",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 37,
      "location_summary": "Hot Springs, Arkansas • Little Rock, Arkansas • Fresno, California + 34 more",
      "locations": [
        {
          "city": "Hot Springs",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Glendale",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00627328"
    },
    {
      "nct_id": "NCT05252702",
      "title": "Aveir DR i2i Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Pacemaker, Artificial",
        "Cardiac Rhythm Disorder",
        "Bradycardia"
      ],
      "interventions": [
        {
          "name": "Aveir DR Leadless Pacemaker System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 464,
      "start_date": "2022-02-02",
      "completion_date": "2026-02-03",
      "has_results": true,
      "last_update_posted_date": "2026-05-27",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 54,
      "location_summary": "Scottsdale, Arizona • Jonesboro, Arkansas • Little Rock, Arkansas + 44 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05252702"
    },
    {
      "nct_id": "NCT02027909",
      "title": "A Comparison of Rate Response Performance in Pacemaker Patients With an Indication of Sinus Node Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sinus Node Dysfunction"
      ],
      "interventions": [
        {
          "name": "Reprogramming dual chamber pacemaker",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Arun Rao",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "60 Years to 95 Years"
      },
      "enrollment_count": 8,
      "start_date": "2011-11",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2018-04-25",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 1,
      "location_summary": "Kingsport, Tennessee",
      "locations": [
        {
          "city": "Kingsport",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02027909"
    },
    {
      "nct_id": "NCT05887323",
      "title": "LBBAP Data Collection Registry",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bradycardia",
        "Sinus Node Dysfunction",
        "Heart Block",
        "Syncope",
        "Cardiomyopathies",
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Implantation of the Tendril 2088 lead in the LBBA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 221,
      "start_date": "2023-04-25",
      "completion_date": "2023-07-11",
      "has_results": true,
      "last_update_posted_date": "2024-10-08",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 5,
      "location_summary": "Jonesboro, Arkansas • Rancho Mirage, California • Pensacola, Florida + 2 more",
      "locations": [
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Rancho Mirage",
          "state": "California"
        },
        {
          "city": "Pensacola",
          "state": "Florida"
        },
        {
          "city": "Tupelo",
          "state": "Mississippi"
        },
        {
          "city": "Danville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05887323"
    },
    {
      "nct_id": "NCT03361189",
      "title": "Specialized Pacing for Patients With Congenital Heart Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Congenital Heart Disease",
        "Bradycardia Sinus"
      ],
      "interventions": [
        {
          "name": "Closed loop stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Standard rate response",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "14 Years to 65 Years"
      },
      "enrollment_count": 4,
      "start_date": "2021-05-09",
      "completion_date": "2021-11-03",
      "has_results": true,
      "last_update_posted_date": "2023-01-20",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03361189"
    },
    {
      "nct_id": "NCT03564860",
      "title": "HBP Device EGM Data Collection",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sick Sinus Syndrome",
        "AV Block",
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Device data collection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2018-07-17",
      "completion_date": "2020-09-30",
      "has_results": false,
      "last_update_posted_date": "2020-10-08",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 3,
      "location_summary": "Huntsville, Alabama • Sayre, Pennsylvania • Greenville, South Carolina",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Sayre",
          "state": "Pennsylvania"
        },
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03564860"
    },
    {
      "nct_id": "NCT03601754",
      "title": "Effectiveness of Closed Loop Stimulation (CLS) With His Bundle Lead Placement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sinus Node Dysfunction"
      ],
      "interventions": [
        {
          "name": "Treadmill/Bicycle exercise testing",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 5,
      "start_date": "2018-07-19",
      "completion_date": "2019-01-31",
      "has_results": false,
      "last_update_posted_date": "2019-11-18",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03601754"
    },
    {
      "nct_id": "NCT02154750",
      "title": "AV Delay Optimization vs. Intrinsic Conduction in Pacemaker Patients With Long PR Intervals",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrioventricular Block",
        "Sick Sinus Syndrome",
        "Symptomatic Bradycardia",
        "Cardiac Arrhythmia"
      ],
      "interventions": [
        {
          "name": "Long, fixed AV delay",
          "type": "DEVICE"
        },
        {
          "name": "Short, optimized AV delay",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2013-06-01",
      "completion_date": "2021-12-31",
      "has_results": true,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-06-26T07:11:06.835Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02154750"
    }
  ]
}