{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Signs+and+Symptoms%2C+Respiratory&page=78",
    "query": {
      "condition": "Signs and Symptoms, Respiratory",
      "page": 78
    },
    "page_size": 10
  },
  "pagination": {
    "page": 78,
    "page_size": 10,
    "total_count": 4724,
    "total_pages": 473,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Signs+and+Symptoms%2C+Respiratory&page=79&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Signs+and+Symptoms%2C+Respiratory&page=77&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-09T16:50:45.714Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02518139",
      "title": "A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease (COPD)"
      ],
      "interventions": [
        {
          "name": "TD-4208",
          "type": "DRUG"
        },
        {
          "name": "Tiotropium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mylan Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 1060,
      "start_date": "2015-09",
      "completion_date": "2017-06",
      "has_results": true,
      "last_update_posted_date": "2022-02-24",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 1,
      "location_summary": "Easley, South Carolina",
      "locations": [
        {
          "city": "Easley",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02518139"
    },
    {
      "nct_id": "NCT05562037",
      "title": "Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Angina, Stable",
        "Congestive Heart Failure",
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "Stepped Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Peter Lindenauer, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 139,
      "start_date": "2022-09-08",
      "completion_date": "2025-03-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 2,
      "location_summary": "Pittsfield, Massachusetts • Springfield, Massachusetts",
      "locations": [
        {
          "city": "Pittsfield",
          "state": "Massachusetts"
        },
        {
          "city": "Springfield",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05562037"
    },
    {
      "nct_id": "NCT06252129",
      "title": "Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lung Cancer",
        "Lymph Node Metastasis",
        "Pathologic Processes"
      ],
      "interventions": [
        {
          "name": "Subjects undergoing a lung specimen lymph node dissection",
          "type": "OTHER"
        },
        {
          "name": "Control group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2024-07-26",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06252129"
    },
    {
      "nct_id": "NCT01435837",
      "title": "Interaction of Caffeine and Hydration on Voice",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Voice Disorders"
      ],
      "interventions": [
        {
          "name": "C2 (200mg of caffeine; 1/2 L of water)",
          "type": "DRUG"
        },
        {
          "name": "C3(200mg of caffeine; 1 L of water)",
          "type": "DRUG"
        },
        {
          "name": "C1 (200mg of caffeine, no water)",
          "type": "DRUG"
        },
        {
          "name": "Placebo (no caffeine, no water).",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Southern Illinois University Carbondale",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 80,
      "start_date": "2010-10",
      "completion_date": "2013-05",
      "has_results": false,
      "last_update_posted_date": "2013-06-11",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 1,
      "location_summary": "Carbondale, Illinois",
      "locations": [
        {
          "city": "Carbondale",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01435837"
    },
    {
      "nct_id": "NCT01320072",
      "title": "Diagnosis of Aspirin Hypersensitivity in Aspirin Exacerbated Respiratory Disease",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Asthma, Aspirin-induced"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 29,
      "start_date": "2010-05",
      "completion_date": "2022-05-26",
      "has_results": true,
      "last_update_posted_date": "2023-02-17",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01320072"
    },
    {
      "nct_id": "NCT06999577",
      "title": "The Mechanism Versus PPI Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Laryngopharyngeal Reflux",
        "Cough",
        "Throat Clearing",
        "Dysphonia",
        "Reflux"
      ],
      "interventions": [
        {
          "name": "Omeprazole 40 MG",
          "type": "DRUG"
        },
        {
          "name": "Laryngeal Recalibration Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "GERD Lifestyle Recommendations",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 160,
      "start_date": "2025-06-04",
      "completion_date": "2029-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-01",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 1,
      "location_summary": "San Deigo, California",
      "locations": [
        {
          "city": "San Deigo",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06999577"
    },
    {
      "nct_id": "NCT00415675",
      "title": "Respiratory Tumor and Normal Tissue Motion",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lung Cancer",
        "Abdominal Cancer"
      ],
      "interventions": [
        {
          "name": "Motion CT Scans",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 86,
      "start_date": "2004-11",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2012-10-23",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00415675"
    },
    {
      "nct_id": "NCT06974981",
      "title": "Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "COPD",
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 420,
      "start_date": "2025-01-02",
      "completion_date": "2027-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-03",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06974981"
    },
    {
      "nct_id": "NCT02637219",
      "title": "Innate Immune Response in COPD",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pulmonary Disease, Chronic Obstructive",
        "Immunity, Innate",
        "Inflammation",
        "Bronchitis, Chronic",
        "Toll-Like Receptors"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "VA Puget Sound Health Care System",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "89 Years",
        "sex": "MALE",
        "summary": "50 Years to 89 Years · Male only"
      },
      "enrollment_count": 30,
      "start_date": "2006-03",
      "completion_date": "2008-01",
      "has_results": false,
      "last_update_posted_date": "2015-12-22",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02637219"
    },
    {
      "nct_id": "NCT04816630",
      "title": "Feasibility Study of Hematology Parameters in COVID-19 Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Covid19",
        "Sepsis",
        "Adults",
        "Emergency Department"
      ],
      "interventions": [
        {
          "name": "CBC-Diff Monocyte Volume Width Distribution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Beckman Coulter, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 32,
      "start_date": "2020-12-21",
      "completion_date": "2021-09-22",
      "has_results": false,
      "last_update_posted_date": "2021-12-07",
      "last_synced_at": "2026-11-09T16:50:45.714Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04816630"
    }
  ]
}