{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Single-ventricle&page=2",
    "query": {
      "condition": "Single-ventricle",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Single-ventricle&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:39:08.859Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05744934",
      "title": "Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Univentricular Heart"
      ],
      "interventions": [
        {
          "name": "LUX-Dx™",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "30 Days",
        "sex": "ALL",
        "summary": "Up to 30 Days"
      },
      "enrollment_count": 10,
      "start_date": "2023-03-15",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05744934"
    },
    {
      "nct_id": "NCT02135081",
      "title": "Cerebral Blood Flow in Single Ventricles Throughout Staged Surgical Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Single Ventricle Defect"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Months",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "4 Months to 10 Years"
      },
      "enrollment_count": 260,
      "start_date": "2008-12",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2018-03-19",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02135081"
    },
    {
      "nct_id": "NCT03575572",
      "title": "Colchicine in Postoperative Fontan Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Single-ventricle",
        "Heart Diseases"
      ],
      "interventions": [
        {
          "name": "Colchicine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Months",
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "20 Months to 5 Years"
      },
      "enrollment_count": 11,
      "start_date": "2018-08-29",
      "completion_date": "2021-01-13",
      "has_results": true,
      "last_update_posted_date": "2022-05-09",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03575572"
    },
    {
      "nct_id": "NCT01169519",
      "title": "Sildenafil in Single Ventricle Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Heart Disease"
      ],
      "interventions": [
        {
          "name": "Sildenafil by injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "120 Months",
        "sex": "ALL",
        "summary": "3 Months to 120 Months"
      },
      "enrollment_count": 21,
      "start_date": "2011-04",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2013-12-05",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01169519"
    },
    {
      "nct_id": "NCT01971580",
      "title": "The Effects of Ambrisentan on Exercise Capacity in Fontan Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Single Ventricle Fontan Palliation"
      ],
      "interventions": [
        {
          "name": "Ambrisentan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 28,
      "start_date": "2012-08",
      "completion_date": "2015-05",
      "has_results": true,
      "last_update_posted_date": "2018-05-07",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01971580"
    },
    {
      "nct_id": "NCT01250912",
      "title": "Imaging With a Radio Tracer to Guide VT Ablations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventricular Tachycardia",
        "Arrhythmia"
      ],
      "interventions": [
        {
          "name": "123I-metaiodobenzylguanidine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2010-03",
      "completion_date": "2019-07-01",
      "has_results": true,
      "last_update_posted_date": "2022-01-27",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01250912"
    },
    {
      "nct_id": "NCT02946892",
      "title": "Effect of Carvedilol on Exercise Performance in Fontan Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Single Ventricle",
        "Fontan"
      ],
      "interventions": [
        {
          "name": "Carvedilol",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "10 Years to 35 Years"
      },
      "enrollment_count": 26,
      "start_date": "2016-11",
      "completion_date": "2020-01",
      "has_results": true,
      "last_update_posted_date": "2021-01-22",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02946892"
    },
    {
      "nct_id": "NCT02462434",
      "title": "Impact of Early Intervention on Maternal Stress in Mothers of Fetuses Diagnosed With Single Ventricle Physiology",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Defects, Congenital",
        "Hypoplastic Left Heart Syndrome",
        "Single Ventricle Defect",
        "Stress, Psychological"
      ],
      "interventions": [
        {
          "name": "Early palliative care team consultation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2013-04",
      "completion_date": "2016-11-15",
      "has_results": false,
      "last_update_posted_date": "2017-04-18",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02462434"
    },
    {
      "nct_id": "NCT03470428",
      "title": "Clinical Characteristics and Associations of the \"Good Fontan\" Patient",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease",
        "Single-ventricle"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "10 Years to 60 Years"
      },
      "enrollment_count": 146,
      "start_date": "2018-03-05",
      "completion_date": "2023-04-18",
      "has_results": false,
      "last_update_posted_date": "2023-04-19",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03470428"
    },
    {
      "nct_id": "NCT01161641",
      "title": "Pilot/Ph I Safety and Efficacy of ODSH in Protein Losing Enteropathy Secondary to Single Ventricle Palliative Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Protein Losing Enteropathy"
      ],
      "interventions": [
        {
          "name": "ODSH at 0.125 mg/kg/h",
          "type": "DRUG"
        },
        {
          "name": "ODSH at 0.375 mg/kg/h",
          "type": "DRUG"
        },
        {
          "name": "ODSH at 0.250 mg/kg/h",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jazz Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2010-07",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2021-12-02",
      "last_synced_at": "2026-05-22T03:39:08.859Z",
      "location_count": 4,
      "location_summary": "Los Angeles, California • Boston, Massachusetts • Ann Arbor, Michigan + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Sioux Falls",
          "state": "South Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01161641"
    }
  ]
}