{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Sjogren+Syndrome", "query": { "condition": "Sjogren Syndrome" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 28, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Sjogren+Syndrome&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-05-22T03:07:33.808Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07277257", "title": "Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Sjogren Syndrome With Keratoconjunctivitis" ], "interventions": [ { "name": "TRYPTYR (Acoltremon ophthalmic solution 0.003%)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Center For Sight", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 35, "start_date": "2025-12-02", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2025-12-22", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 1, "location_summary": "Venice, Florida", "locations": [ { "city": "Venice", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07277257" }, { "nct_id": "NCT04806620", "title": "Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Post-Acute COVID-19 Syndrome", "ME/CFS", "Rheumatic Arthritis", "Juvenile Rheumatoid Arthritis (JRA)", "Psoriatic Arthritis (PsA)", "Ankylosing Spondylitis (AS)", "Autoimmune Encephalitis", "Celiac Disease", "Celiac Disease in Children", "Chronic Lyme Disease", "Post-treatment Lyme Disease Syndrome", "Crohn's Disease", "Dysautonomia", "Anorexia Nervosa", "Bulimia Nervosa", "ARFID", "Avoidant / Restrictive Food Intake Disorder", "Ehlers Danlos Syndrome", "Endometriosis", "Fibromyalgia (FM)", "Long COVID", "Lupus", "Migraines", "Mast Cell Activation Syndrome", "Multiple Sclerosis", "Myalgic Encephalomyelitis (ME)", "Myasthenia Gravis, Generalized", "Myasthenia Gravis in Children", "Narcolepsy", "Obsessive Compulsive Disorder (OCD)", "PANDAS", "Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)", "POTS - Postural Orthostatic Tachycardia Syndrome", "General Anxiety Disorder, Social Anxiety Disorder", "PTSD - Post Traumatic Stress Disorder", "Psoriasis", "Traumatic Brain Injury", "Tourette's Syndrome", "Inflammatory Bowel Disease (IBD)", "Autoimmune Diseases", "Neurological Diseases or Conditions", "Psychiatric Disorder", "Sjogren's Syndrome", "Ulcerative Colitis and Crohn's Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Brain Inflammation Collaborative", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "2 Years", "maximum_age": null, "sex": "ALL", "summary": "2 Years and older" }, "enrollment_count": 10000, "start_date": "2023-07-05", "completion_date": "2030-12-31", "has_results": false, "last_update_posted_date": "2026-01-22", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 1, "location_summary": "Delafield, Wisconsin", "locations": [ { "city": "Delafield", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04806620" }, { "nct_id": "NCT00565526", "title": "Evaluation of the Role of the Autonomic Nervous System in Sj(SqrRoot)(Delta)Gren s Syndrome", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Sjogren's Syndrome", "Dysautonomia" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 28, "start_date": "2007-11-26", "completion_date": "2014-04-10", "has_results": false, "last_update_posted_date": "2018-07-05", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00565526" }, { "nct_id": "NCT03047369", "title": "The Myelin Disorders Biorepository Project", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Leukodystrophy", "White Matter Disease", "Leukoencephalopathies", "4H Syndrome", "Adrenoleukodystrophy", "AMN", "ALD", "ALD Gene Mutation", "ALD (Adrenoleukodystrophy)", "X-linked Adrenoleukodystrophy", "X-ALD", "Adrenomyeloneuropathy", "Aicardi Goutieres Syndrome", "AGS", "Alexander Disease", "Alexanders Leukodystrophy", "AxD", "ADLD", "Canavan Disease", "CTX", "Cerebrotendinous Xanthomatoses", "Krabbe Disease", "GALC Deficiency", "Globoid Leukodystrophy", "TUBB4A-Related Leukodystrophy", "H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum", "HBSL", "HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity", "LBSL", "Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)", "Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation", "ALSP", "CSF1R Gene Mutation", "HCC - Hypomyelination and Congenital Cataract", "MLC1", "Megalencephalic Leukoencephalopathy With Subcortical Cysts", "MLD", "Metachromatic Leukodystrophy", "PMD", "Pelizaeus-Merzbacher Disease", "PLP1 Null Syndrome", "PLP1 Gene Duplication | Blood or Tissue | Mutations", "Pelizaeus Merzbacher Like Disease", "Peroxisomal Biogenesis Disorder", "Zellweger Syndrome", "Refsum Disease", "Salla Disease", "Sialic Storage Disease", "Sjögren", "Sjogren-Larsson Syndrome", "Van Der Knapp Disease", "Vanishing White Matter Disease", "Charcot-Marie-Tooth", "CMT", "Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency", "Allan-Herndon-Dudley Syndrome", "Cadasil", "Cockayne Syndrome", "Multiple Sulfatase Deficiency", "Gangliosidoses", "GM2 Gangliosidosis", "BPAN", "Labrune Syndrome", "LCC", "Mucopolysaccharidoses", "TBCK-Related Intellectual Disability Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 12000, "start_date": "2016-12-08", "completion_date": "2030-12-08", "has_results": false, "last_update_posted_date": "2025-10-23", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 23, "location_summary": "Los Angeles, California • Orange, California • Palo Alto, California + 18 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03047369" }, { "nct_id": "NCT07281456", "title": "Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Sjogren's Syndrome" ], "interventions": [ { "name": "Tofacitinib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 60, "start_date": "2025-12-18", "completion_date": "2030-12-15", "has_results": false, "last_update_posted_date": "2026-05-19", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT07281456" }, { "nct_id": "NCT03327870", "title": "Oral Health Needs Assessment of Sjogren s Syndrome and Salivary Gland Dysfunction Cohorts and Healthy Volunteers Evaluating Oral Health Disparities as Determinants of Oral Health in a High-Risk Population", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Sjogren's Syndrome", "Oral Health" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 166, "start_date": "2018-05-01", "completion_date": "2018-10-16", "has_results": false, "last_update_posted_date": "2019-10-24", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03327870" }, { "nct_id": "NCT02193490", "title": "DNase Treatment for Dry Eyes", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Dry Eye" ], "interventions": [ { "name": "DNase", "type": "DRUG" }, { "name": "Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Illinois at Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 47, "start_date": "2014-07", "completion_date": "2017-10-11", "has_results": true, "last_update_posted_date": "2020-01-18", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02193490" }, { "nct_id": "NCT04313725", "title": "Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Stevens-Johnson Syndrome", "Graft Versus Host Disease in Eye", "Sjogren's Syndrome", "Dry Eye" ], "interventions": [ { "name": "Tangible Boost", "type": "DEVICE" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Tangible Science", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2020-02-24", "completion_date": "2023-06-21", "has_results": false, "last_update_posted_date": "2025-09-16", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 1, "location_summary": "Needham, Massachusetts", "locations": [ { "city": "Needham", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04313725" }, { "nct_id": "NCT05349214", "title": "Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Sjogren Syndrome" ], "interventions": [ { "name": "VAY736", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "OTHER" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 506, "start_date": "2022-08-04", "completion_date": "2027-05-13", "has_results": false, "last_update_posted_date": "2026-03-11", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 23, "location_summary": "Fullerton, California • La Palma, California • Brandon, Florida + 19 more", "locations": [ { "city": "Fullerton", "state": "California" }, { "city": "La Palma", "state": "California" }, { "city": "Brandon", "state": "Florida" }, { "city": "Cooper City", "state": "Florida" }, { "city": "Sarasota", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05349214" }, { "nct_id": "NCT00460928", "title": "Preventive IVIG Therapy for Congenital Heart Block", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Congenital Heart Block", "Neonatal Lupus", "Autoantibody-associated Heart Block" ], "interventions": [ { "name": "intravenous immune globulin (IVIG)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "FEMALE", "summary": "18 Years to 50 Years · Female only" }, "enrollment_count": 20, "start_date": "2007-04", "completion_date": "2009-06", "has_results": false, "last_update_posted_date": "2019-09-30", "last_synced_at": "2026-05-22T03:07:33.808Z", "location_count": 2, "location_summary": "Livingston, New Jersey • New York, New York", "locations": [ { "city": "Livingston", "state": "New Jersey" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00460928" } ] }