{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Skin+Substitutes&page=2",
    "query": {
      "condition": "Skin Substitutes",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Skin+Substitutes&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T05:14:53.085Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01970163",
      "title": "DermACELL in Subjects With Chronic Wounds of the Lower Extremities",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "DermACELL",
          "type": "OTHER"
        },
        {
          "name": "GraftJacket",
          "type": "OTHER"
        },
        {
          "name": "Conventional Care Dressings",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "LifeNet Health",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 202,
      "start_date": "2013-10",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2018-03-14",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 12,
      "location_summary": "Montgomery, Alabama • Tucson, Arizona • Carlsbad, California + 8 more",
      "locations": [
        {
          "city": "Montgomery",
          "state": "Alabama"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Carlsbad",
          "state": "California"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01970163"
    },
    {
      "nct_id": "NCT01933724",
      "title": "The Assessment of Prednisone In Remission Trial (TAPIR) - Patient Centric Approach",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Granulomatosis With Polyangiitis",
        "Wegener Granulomatosis",
        "Vasculitis"
      ],
      "interventions": [
        {
          "name": "5 mg prednisone",
          "type": "DRUG"
        },
        {
          "name": "0 mg prednisone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2014-02-17",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-07-29",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01933724"
    },
    {
      "nct_id": "NCT02422615",
      "title": "Study of Efficacy and Safety of LEE011 in Men and Postmenopausal Women With Advanced Breast Cancer.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Advanced Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Ribociclib",
          "type": "DRUG"
        },
        {
          "name": "Fulvestrant",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 726,
      "start_date": "2015-06-09",
      "completion_date": "2023-01-11",
      "has_results": true,
      "last_update_posted_date": "2023-11-30",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 26,
      "location_summary": "Mobile, Alabama • Chandler, Arizona • Fayetteville, Arkansas + 22 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Santa Maria",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02422615"
    },
    {
      "nct_id": "NCT02081352",
      "title": "A Comparative Efficacy Study of DermaPure™ to Treat Diabetic Foot Ulcers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "DermaPure™",
          "type": "OTHER"
        },
        {
          "name": "Standard care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "TRx Wound Care Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2014-08",
      "completion_date": "2017-02",
      "has_results": false,
      "last_update_posted_date": "2015-11-05",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 7,
      "location_summary": "Phoenix, Arizona • Miami, Florida • New York, New York + 3 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02081352"
    },
    {
      "nct_id": "NCT01676272",
      "title": "Multi Center Site , Controlled Trial Comparing a Bioengineered Skin Substitute to a Human Skin Allograft",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Solsys Medical LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 23,
      "start_date": "2012-07",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2019-06-26",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 2,
      "location_summary": "Washington, Pennsylvania • Newport News, Virginia",
      "locations": [
        {
          "city": "Washington",
          "state": "Pennsylvania"
        },
        {
          "city": "Newport News",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01676272"
    },
    {
      "nct_id": "NCT07223515",
      "title": "HEAL-4: Real-World Effectiveness of 4 Amniotic Allografts Adjunctive to Standard Care in DFU, VLU, and PU",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)",
        "Venous Leg Ulcers (VLUs)",
        "Pressure Ulcers, Bedsores, Decubitus Ulcer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dynamic Medical Services dba Acesso Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2025-10-24",
      "completion_date": "2025-11",
      "has_results": false,
      "last_update_posted_date": "2025-11-03",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 2,
      "location_summary": "Novi, Michigan • Murfreesboro, Tennessee",
      "locations": [
        {
          "city": "Novi",
          "state": "Michigan"
        },
        {
          "city": "Murfreesboro",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223515"
    },
    {
      "nct_id": "NCT04673435",
      "title": "Permeaderm Versus Homograft for Full-thickness Burns",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Full Thickness Burn"
      ],
      "interventions": [
        {
          "name": "PermeaDerm for temporary coverage",
          "type": "DEVICE"
        },
        {
          "name": "FHCA for temporary coverage",
          "type": "DEVICE"
        },
        {
          "name": "PermeaDerm over autograft",
          "type": "DEVICE"
        },
        {
          "name": "FHCA over autograft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Months and older"
      },
      "enrollment_count": 0,
      "start_date": "2018-01-31",
      "completion_date": "2020-07-31",
      "has_results": false,
      "last_update_posted_date": "2020-12-17",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04673435"
    },
    {
      "nct_id": "NCT02870816",
      "title": "Prospective, Comparitive, Randomized Study of Allograft Versus Skin Substitute in Non-healing Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "Tissue Engineered Skin Substitute",
          "type": "PROCEDURE"
        },
        {
          "name": "Offloading",
          "type": "DEVICE"
        },
        {
          "name": "Amnionic Membrane Graft",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Professional Education and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2016-08-31",
      "completion_date": "2018-06-14",
      "has_results": false,
      "last_update_posted_date": "2021-12-08",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 3,
      "location_summary": "Martinsville, Virginia • Roanoke, Virginia",
      "locations": [
        {
          "city": "Martinsville",
          "state": "Virginia"
        },
        {
          "city": "Roanoke",
          "state": "Virginia"
        },
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02870816"
    },
    {
      "nct_id": "NCT06449638",
      "title": "Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)",
        "Ulcer Foot",
        "Diabetic Foot",
        "Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "Standard of Care",
          "type": "OTHER"
        },
        {
          "name": "Revita",
          "type": "OTHER"
        },
        {
          "name": "Relese",
          "type": "OTHER"
        },
        {
          "name": "Cogenex",
          "type": "OTHER"
        },
        {
          "name": "Enverse",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "StimLabs",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 272,
      "start_date": "2024-07-16",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 5,
      "location_summary": "Omaha, Nebraska • Tulsa, Oklahoma • Jefferson Hills, Pennsylvania + 2 more",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        },
        {
          "city": "Jefferson Hills",
          "state": "Pennsylvania"
        },
        {
          "city": "Kittanning",
          "state": "Pennsylvania"
        },
        {
          "city": "Monroeville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06449638"
    },
    {
      "nct_id": "NCT02047084",
      "title": "Comparison of Human Allograft to Apligraf for Venous Leg Ulcers",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Venous Leg Ulcers"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Solsys Medical LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "21 Years to 90 Years"
      },
      "enrollment_count": 50,
      "start_date": "2013-06",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-29",
      "last_synced_at": "2026-07-23T05:14:53.085Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02047084"
    }
  ]
}