{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Skin+Wrinkling&page=3",
    "query": {
      "condition": "Skin Wrinkling",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 119,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Skin+Wrinkling&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Skin+Wrinkling&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T14:13:51.757Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05773924",
      "title": "Evaluation of Efficacy and Safety of the triLift™ System",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Laxity",
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "triLift system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Lumenis Be Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "35 Years to 55 Years"
      },
      "enrollment_count": 25,
      "start_date": "2023-02-10",
      "completion_date": "2023-08-15",
      "has_results": false,
      "last_update_posted_date": "2023-03-17",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05773924"
    },
    {
      "nct_id": "NCT03228641",
      "title": "Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle",
        "Facial and Neck Skin Laxity"
      ],
      "interventions": [
        {
          "name": "micro-excisional skin removal with coring needle",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cytrellis Biosystems, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 45,
      "start_date": "2016-06-01",
      "completion_date": "2017-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-25",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 6,
      "location_summary": "Sacramento, California • Miami, Florida • Chestnut Hill, Massachusetts + 3 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Chestnut Hill",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03228641"
    },
    {
      "nct_id": "NCT05987163",
      "title": "Study to Evaluate the Safety and Effectiveness of GP0116",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Manifestations"
      ],
      "interventions": [
        {
          "name": "GP0116",
          "type": "DEVICE"
        },
        {
          "name": "Active Comparator: FDA approved dermal filler device (RHA 3)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 186,
      "start_date": "2023-04-12",
      "completion_date": "2026-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-02",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 18,
      "location_summary": "Santa Monica, California • Vista, California • Westport, Connecticut + 14 more",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Vista",
          "state": "California"
        },
        {
          "city": "Westport",
          "state": "Connecticut"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05987163"
    },
    {
      "nct_id": "NCT03583918",
      "title": "Efficacy of Micro-excisional Skin Removal by Micro-coring Device in Treatment of Wrinkles and Laxity of Face and Neck",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Laxity; Skin"
      ],
      "interventions": [
        {
          "name": "HighThroughput Micro Coring Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cytrellis Biosystems, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 50,
      "start_date": "2017-06-01",
      "completion_date": "2018-06-13",
      "has_results": false,
      "last_update_posted_date": "2018-07-12",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 5,
      "location_summary": "Sacramento, California • Miami, Florida • New York, New York + 2 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03583918"
    },
    {
      "nct_id": "NCT01771679",
      "title": "Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chronic Effect of Ultraviolet Radiation on Photoaged Skin",
        "Dermatologic Disorders"
      ],
      "interventions": [
        {
          "name": "Allogeneic Mesenchymal Bone Marrow Cells",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Stemedica Cell Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 29,
      "start_date": "2015-07-01",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-10-31",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 2,
      "location_summary": "La Mesa, California • San Diego, California",
      "locations": [
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01771679"
    },
    {
      "nct_id": "NCT01828723",
      "title": "Safety Study of Antria Cell Preparation Process to Enhance Facial Fat Grafting With Adipose Derived Stem Cells",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Lipoatrophy",
        "Aging",
        "Wrinkles"
      ],
      "interventions": [
        {
          "name": "SVF",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Antria",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2013-04",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2015-01-27",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 1,
      "location_summary": "Greensburg, Pennsylvania",
      "locations": [
        {
          "city": "Greensburg",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01828723"
    },
    {
      "nct_id": "NCT02954315",
      "title": "The Effect of Almonds on Skin Lipids and Wrinkles",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rhytides"
      ],
      "interventions": [
        {
          "name": "Almonds",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 31,
      "start_date": "2016-10-25",
      "completion_date": "2018-04-30",
      "has_results": false,
      "last_update_posted_date": "2018-10-17",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02954315"
    },
    {
      "nct_id": "NCT06604832",
      "title": "Effects of Microtox on Facial Skin Quality, Fine Wrinkles, and Texture",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Skin Aging",
        "Skin Wrinkling"
      ],
      "interventions": [
        {
          "name": "PrabotulinumtoxinA-Xvfs",
          "type": "DRUG"
        },
        {
          "name": "IncobotulinumtoxinA",
          "type": "DRUG"
        },
        {
          "name": "saline solution (placebo)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kalpna Kay Durairaj, MD, FACS",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 20,
      "start_date": "2024-09-03",
      "completion_date": "2025-09-16",
      "has_results": false,
      "last_update_posted_date": "2025-10-21",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 1,
      "location_summary": "Pasadena, California",
      "locations": [
        {
          "city": "Pasadena",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06604832"
    },
    {
      "nct_id": "NCT05688527",
      "title": "The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "Cleansing Balm",
          "type": "OTHER"
        },
        {
          "name": "Toning Essence",
          "type": "OTHER"
        },
        {
          "name": "Facial Serum",
          "type": "OTHER"
        },
        {
          "name": "Moisturizer",
          "type": "OTHER"
        },
        {
          "name": "Eye Cream",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Integrative Skin Science and Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "35 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2023-01-23",
      "completion_date": "2023-12-16",
      "has_results": false,
      "last_update_posted_date": "2023-07-25",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05688527"
    },
    {
      "nct_id": "NCT06623214",
      "title": "Assessment of the Safety and Effectiveness of a Micro-RF Skin Treatment Device (nebulyft）",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle Reduction"
      ],
      "interventions": [
        {
          "name": "nebulyft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Hangzhou Rebecca Medical Science and Technology Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "25 Years to 65 Years"
      },
      "enrollment_count": 42,
      "start_date": "2024-06-07",
      "completion_date": "2024-08-13",
      "has_results": false,
      "last_update_posted_date": "2024-10-03",
      "last_synced_at": "2026-10-23T14:13:51.757Z",
      "location_count": 1,
      "location_summary": "San Gabriel, California",
      "locations": [
        {
          "city": "San Gabriel",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06623214"
    }
  ]
}