{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Small+Intestinal+Bacterial+Overgrowth",
    "query": {
      "condition": "Small Intestinal Bacterial Overgrowth"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 32,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Small+Intestinal+Bacterial+Overgrowth&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T00:47:30.056Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04867512",
      "title": "Botanical Blend on the Gut Microbiome and Gut-Skin-Axis in Small Intestinal Bacterial Overgrowth (SIBO)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Small Intestinal Bacterial Overgrowth (SIBO)"
      ],
      "interventions": [
        {
          "name": "Liquid Tincture",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "GI Detox",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Olivirex",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Integrative Skin Science and Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 35,
      "start_date": "2021-04-27",
      "completion_date": "2022-02-01",
      "has_results": false,
      "last_update_posted_date": "2021-05-04",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04867512"
    },
    {
      "nct_id": "NCT01662791",
      "title": "Weight Loss in Parkinson's Disease and Role of Small Bowel Bacterial Overgrowth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "Rifaximin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2012-09",
      "completion_date": "2015-03",
      "has_results": true,
      "last_update_posted_date": "2016-08-04",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "Scottsdale, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01662791"
    },
    {
      "nct_id": "NCT00844831",
      "title": "Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut Transit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Constipation"
      ],
      "interventions": [
        {
          "name": "Lubiprostone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 25,
      "start_date": "2009-05",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2017-07-27",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00844831"
    },
    {
      "nct_id": "NCT06298409",
      "title": "Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan®",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Small Intestinal Bacterial Overgrowth"
      ],
      "interventions": [
        {
          "name": "CapScan collection capsule",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Envivo Bio Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 34,
      "start_date": "2024-02-15",
      "completion_date": "2026-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-06-11",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "Mountain View, California",
      "locations": [
        {
          "city": "Mountain View",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06298409"
    },
    {
      "nct_id": "NCT01324895",
      "title": "Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Small Intestinal Bacterial Overgrowth Syndrome (SIBO)",
        "Small Bowel Bacterial Overgrowth Syndrome (SBBOS)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 944,
      "start_date": "2010-08",
      "completion_date": "2012-03",
      "has_results": false,
      "last_update_posted_date": "2012-03-26",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01324895"
    },
    {
      "nct_id": "NCT04499742",
      "title": "Comparative Assessment of Radioisotope Glucose and Breath Test",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Small Intestinal Bacterial Overgrowth"
      ],
      "interventions": [
        {
          "name": "Using Isotope (Tc99m-Sulfur Colloid) to label glucose and administer this directly into duodenum.",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 25,
      "start_date": "2019-01-21",
      "completion_date": "2021-12-14",
      "has_results": false,
      "last_update_posted_date": "2020-08-05",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04499742"
    },
    {
      "nct_id": "NCT07215676",
      "title": "A Trial of a Multi-Component Nutritional Supplement in Hydrogen-Dominant Small Intestinal Bacterial Overgrowth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Small Intestinal Bacterial Overgrowth Syndrome (SIBO)",
        "Small Intestinal Bacterial Overgrowth"
      ],
      "interventions": [
        {
          "name": "AV1PD1A",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "National University of Natural Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2025-10-10",
      "completion_date": "2026-02-25",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07215676"
    },
    {
      "nct_id": "NCT04501380",
      "title": "Efficacy of AEMCOLO (Rifamycin SV MMX) in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Small Intestinal Bacterial Overgrowth",
        "Gastrointestinal Disease",
        "Gastrointestinal Infection"
      ],
      "interventions": [
        {
          "name": "AEMCOLO (Rifamycin SV MMX)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bradley Connor",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 30,
      "start_date": "2020-06-30",
      "completion_date": "2022-12-30",
      "has_results": false,
      "last_update_posted_date": "2022-05-05",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04501380"
    },
    {
      "nct_id": "NCT03420976",
      "title": "Novel Supplement-based Therapy for the Treatment of Small Intestinal Bacterial Overgrowth",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Small Intestinal Bacterial Overgrowth"
      ],
      "interventions": [
        {
          "name": "Novel Supplement Based Therapy",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Atrium Innovations",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "19 Years to 84 Years"
      },
      "enrollment_count": 0,
      "start_date": "2017-12-07",
      "completion_date": "2019-02-01",
      "has_results": false,
      "last_update_posted_date": "2021-01-12",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "Oxford, Ohio",
      "locations": [
        {
          "city": "Oxford",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03420976"
    },
    {
      "nct_id": "NCT04506593",
      "title": "Indiana University Gastrointestinal Motility Diagnosis Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Eosinophilic Esophagitis",
        "Gastroesophageal Reflux Disease (GERD)",
        "Gastroparesis",
        "Functional Vomiting",
        "Irritable Bowel Syndrome (IBS)",
        "Constipation",
        "Chronic Intestinal Pseudo-obstruction",
        "Fecal Incontinence",
        "Small Intestinal Bacterial Overgrowth"
      ],
      "interventions": [
        {
          "name": "no intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 5000,
      "start_date": "2014-11",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2024-08-15",
      "last_synced_at": "2026-05-22T00:47:30.056Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04506593"
    }
  ]
}