{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Spinal+Dysraphism&page=5",
    "query": {
      "condition": "Spinal Dysraphism",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 100,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Spinal+Dysraphism&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Spinal+Dysraphism&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T20:17:24.651Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00717600",
      "title": "Bacteriuria Eradication Through Probiotics",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Bacteriuria"
      ],
      "interventions": [
        {
          "name": "Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "FEMALE",
        "summary": "Up to 18 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2008-01",
      "completion_date": "2008-09",
      "has_results": false,
      "last_update_posted_date": "2008-07-17",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00717600"
    },
    {
      "nct_id": "NCT04362592",
      "title": "In-Utero Endoscopic Correction of Spina Bifida",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neural Tube Defects",
        "Spina Bifida",
        "Myelomeningocele"
      ],
      "interventions": [
        {
          "name": "In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique",
          "type": "DEVICE"
        },
        {
          "name": "In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization Technique",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "52 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 52 Years · Female only"
      },
      "enrollment_count": 110,
      "start_date": "2018-11-02",
      "completion_date": "2031-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • Wellington, Florida",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Wellington",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04362592"
    },
    {
      "nct_id": "NCT00341068",
      "title": "Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish Population",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neural Tube Defects (NTDs)",
        "Facial Cleft Defect",
        "Hereditary Oral Clefts"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Human Genome Research Institute (NHGRI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "Up to 85 Years"
      },
      "enrollment_count": 7451,
      "start_date": "2000-01-01",
      "completion_date": "2019-12-02",
      "has_results": false,
      "last_update_posted_date": "2019-12-05",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00341068"
    },
    {
      "nct_id": "NCT07136688",
      "title": "Tibial Nerve Stimulation for Pediatric Spina Bifida Neurogenic Bladder",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurogenic Bladder Due to Spina Bifida"
      ],
      "interventions": [
        {
          "name": "Stamobil electric stimulator",
          "type": "DEVICE"
        },
        {
          "name": "sham tTNS device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "4 Years to 17 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-03-27",
      "completion_date": "2027-08-11",
      "has_results": false,
      "last_update_posted_date": "2026-09-10",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07136688"
    },
    {
      "nct_id": "NCT01150708",
      "title": "A Prospective Natural History Study of Patients With Syringomyelia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Syringomyelia",
        "Arnold Chiari Deformity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 180,
      "start_date": "2010-08-03",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-10-16",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01150708"
    },
    {
      "nct_id": "NCT04652908",
      "title": "Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Myelomeningocele"
      ],
      "interventions": [
        {
          "name": "Placental Mesenchymal Stem Cells seeded on a commercially available dural graft extracellular matrix",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Untreated contemporaneous cohort",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Weeks",
        "maximum_age": "25 Weeks",
        "sex": "ALL",
        "summary": "19 Weeks to 25 Weeks"
      },
      "enrollment_count": 55,
      "start_date": "2021-06-21",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04652908"
    },
    {
      "nct_id": "NCT00031122",
      "title": "Study of Genetic Risk Factors for Spina Bifida and Anencephaly",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spina Bifida",
        "Anencephaly"
      ],
      "interventions": [
        {
          "name": "No Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1100,
      "start_date": "2000-09",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2010-10-05",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania • Houston, Texas",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00031122"
    },
    {
      "nct_id": "NCT04251806",
      "title": "Sleep-disordered Breathing in Infants With Myelomeningocele",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sleep-disordered Breathing",
        "Myelomeningocele"
      ],
      "interventions": [
        {
          "name": "neonatal polysomnography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "2-year Bayley Exam",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "2-year polysomnography",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "Up to 2 Years"
      },
      "enrollment_count": 173,
      "start_date": "2020-07-21",
      "completion_date": "2026-05-19",
      "has_results": false,
      "last_update_posted_date": "2026-05-27",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 9,
      "location_summary": "Birmingham, Alabama • Aurora, Colorado • Ann Arbor, Michigan + 6 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04251806"
    },
    {
      "nct_id": "NCT03044821",
      "title": "Open Myelomeningocele Repair With High Maternal BMI",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neural Tube Defect"
      ],
      "interventions": [
        {
          "name": "Open-Uterus Fetal Repair",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 1,
      "start_date": "2018-07-18",
      "completion_date": "2019-07-16",
      "has_results": false,
      "last_update_posted_date": "2019-08-01",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03044821"
    },
    {
      "nct_id": "NCT05951985",
      "title": "High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurologic Disorder",
        "Parkinson Disease",
        "Spinal Cord Injuries",
        "Spina Bifida",
        "Stroke",
        "Poliomyelitis",
        "Multiple Sclerosis",
        "Brain Injuries"
      ],
      "interventions": [
        {
          "name": "HIFT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arkansas Colleges of Health Education",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2023-08-15",
      "completion_date": "2025-08-14",
      "has_results": false,
      "last_update_posted_date": "2025-08-22",
      "last_synced_at": "2026-10-22T20:17:24.651Z",
      "location_count": 1,
      "location_summary": "Fort Smith, Arkansas",
      "locations": [
        {
          "city": "Fort Smith",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05951985"
    }
  ]
}